Arterial Spin Labeling Perfusion Imaging.


Journal

Magnetic resonance imaging clinics of North America
ISSN: 1557-9786
Titre abrégé: Magn Reson Imaging Clin N Am
Pays: United States
ID NLM: 9422762

Informations de publication

Date de publication:
Feb 2024
Historique:
medline: 27 11 2023
pubmed: 26 11 2023
entrez: 25 11 2023
Statut: ppublish

Résumé

Noninvasive imaging of tissue perfusion is a valuable tool for both research and clinical applications. Arterial spin labeling (ASL) is a contrast-free perfusion imaging method that enables measuring and quantifying tissue blood flow using MR imaging. ASL uses radiofrequency and magnetic field gradient pulses to label arterial blood water, which then serves as an endogenous tracer. This review highlights the basic mechanism of ASL perfusion imaging, labeling strategies, and quantification. ASL has been widely used during the past 30 years for the study of normal brain function as well as in multiple neurovascular, neuro-oncological and degenerative pathologic conditions.

Identifiants

pubmed: 38007283
pii: S1064-9689(23)00066-1
doi: 10.1016/j.mric.2023.08.005
pii:
doi:

Substances chimiques

Spin Labels 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

63-72

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosures M. Taso is now an employee of Siemens Medical Solutions USA. D.C. Alsop receives royalties through his institution from GE, Siemens, Philips, Hitachi, and UIH America for patents related to pseudocontinuous ASL methods.

Auteurs

Manuel Taso (M)

Division of MRI Research, Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

David C Alsop (DC)

Division of MRI Research, Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA. Electronic address: dalsop@bidmc.harvard.edu.

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Classifications MeSH