Effect of Lumenato a Tomato derived oral supplement on improving skin barrier strength.
carotenes
facial ageing
oral supplement
skin barrier
Journal
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
ISSN: 1600-0846
Titre abrégé: Skin Res Technol
Pays: England
ID NLM: 9504453
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
02
10
2023
accepted:
09
10
2023
medline:
28
11
2023
pubmed:
27
11
2023
entrez:
27
11
2023
Statut:
ppublish
Résumé
Improvement of skin barrier strength could lead to healthy and youthful appearance. "Beauty inside-out" approach using nutraceuticals such as tomato derived carotenoids to support skin barrier strength could be of benefit to the ageing population. A panel of 60 female subjects were provided with the Lumenato capsules (containing carotenoids) or placebo capsules as nutritional supplements for 3 months. Skin health and barrier function were observed using evaporimeter which measures trans epidermal water loss (TEWL). Barrier strength was determined by study of the number of strippings required to disrupt skin barrier and barrier repair was observed in terms of TEWL a few hours after barrier disruption. Cutometer was used to observe skin firmness and elasticity. Measurements were obtained before treatment and after 4 and 12 weeks of use. Results indicated a statistically significant improvement (p < 0.05) in skin barrier strength; a higher number of strippings were required to disrupt skin barrier after 12 weeks of supplement use. There was also a significant improvement in skin firmness and elasticity as observed with a cutometer. Based on the confines and conditions of this study, oral supplementation with Lumenato resulted in significant improvement in skin barrier as well as skin firmness and elasticity.
Identifiants
pubmed: 38009018
doi: 10.1111/srt.13504
pmc: PMC10632383
doi:
Substances chimiques
Carotenoids
36-88-4
Water
059QF0KO0R
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13504Subventions
Organisme : Lycored Ltd, Beer Shiva, Israel
Informations de copyright
© 2023 Lycored. Skin Research and Technology published by John Wiley & Sons Ltd.
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