Role of Bradykinin and Prostaglandin EP4 Receptors in Regulating TRPV1 Channel Sensitization in Rat Dorsal Root Ganglion Neurons.

Bradykinin Prostaglandins Transient receptor potential vanilloid type-1 (TRPV1) cyclooxygenase-1 (COX-1)

Journal

Basic & clinical pharmacology & toxicology
ISSN: 1742-7843
Titre abrégé: Basic Clin Pharmacol Toxicol
Pays: England
ID NLM: 101208422

Informations de publication

Date de publication:
27 Nov 2023
Historique:
revised: 23 10 2023
received: 10 05 2023
accepted: 22 11 2023
medline: 27 11 2023
pubmed: 27 11 2023
entrez: 27 11 2023
Statut: aheadofprint

Résumé

Transient receptor potential vanilloid type-1 (TRPV1) channels play key roles in chronic pain conditions and are modulated by different inflammatory mediators to elicit heat sensitisation. Bradykinin is a 9-amino acid peptide chain that promotes inflammation. The aim of present study is to investigate how bradykinin and prostaglandin receptors (EP

Identifiants

pubmed: 38009541
doi: 10.1111/bcpt.13967
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

This article is protected by copyright. All rights reserved.

Auteurs

Sara A Aldossary (SA)

Faculty of Clinical Pharmacy, King Faisal University, Hofuf, Saudi Arabia.

Mohammad Alsalem (M)

School of Medicine, The University of Jordan, Amman, Jordan.

Blair D Grubb (BD)

Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

Classifications MeSH