Safety and feasibility of Pulmonary Rehabilitation in patients hospitalized with post-COVID-19 fibrosis: A feasibility study.
Journal
PM & R : the journal of injury, function, and rehabilitation
ISSN: 1934-1563
Titre abrégé: PM R
Pays: United States
ID NLM: 101491319
Informations de publication
Date de publication:
27 Nov 2023
27 Nov 2023
Historique:
revised:
24
09
2023
received:
10
11
2022
accepted:
11
11
2023
medline:
27
11
2023
pubmed:
27
11
2023
entrez:
27
11
2023
Statut:
aheadofprint
Résumé
Emerging data suggests a spectrum of pulmonary complications from COVID-19, ranging from dyspnea to difficult ventilator weaning and fibrotic lung damage. Prolonged hospitalization is known to significantly affect activity levels, impair muscle strength and reduce cardio-pulmonary endurance. To assess the feasibility and safety of inpatient pulmonary rehabilitation (PR) and to explore effects on functional capacity, physical performance, fatigue levels and functional status. A prospective feasibility study. Inpatient unit of a tertiary care hospital. Twenty-five hospitalized patients diagnosed with post-COVID-19 fibrosis referred for pulmonary rehabilitation (PR). Individualized PR intervention including breathing exercises, positioning, strengthening, functional training and ambulation twice a day for six days a week. One minute Sit to Stand Test (STST), Short Physical Performance Battery (SPPB), Fatigue Assessment Scale (FAS) and Post-COVID-19 Functional status Scale (PCFS). Twenty-five participants (males-19, females-6) with a mean age of 54.25 ± 13.36 years were enrolled. Sixteen completed the two-point assessment after undergoing in-patient PR of mean duration 14.8 ± 9 days. PR led to a significant improvement in all functional outcomes i.e., STST (from 7.1 ± 4.3 repetitions to 14.2 ± 2.1 repetitions, SPPB (from 5 ± 2.8 to 9.4 ± 1.5), FAS (from 33.3 ± 10.8 to 25.8 ± 4.7) at the p value ≤0.001 and PCFS (from 3.6 ± 0.9 to 2.9 ± 1.2, p value ≤0.05). Early initiation of PR for hospitalized patients with COVID-19 fibrosis was found to be safe, well-tolerated and feasible and may improve functional status. This article is protected by copyright. All rights reserved.
Sections du résumé
BACKGROUND
BACKGROUND
Emerging data suggests a spectrum of pulmonary complications from COVID-19, ranging from dyspnea to difficult ventilator weaning and fibrotic lung damage. Prolonged hospitalization is known to significantly affect activity levels, impair muscle strength and reduce cardio-pulmonary endurance.
OBJECTIVE
OBJECTIVE
To assess the feasibility and safety of inpatient pulmonary rehabilitation (PR) and to explore effects on functional capacity, physical performance, fatigue levels and functional status.
DESIGN
METHODS
A prospective feasibility study.
SETTING
METHODS
Inpatient unit of a tertiary care hospital.
PARTICIPANTS
METHODS
Twenty-five hospitalized patients diagnosed with post-COVID-19 fibrosis referred for pulmonary rehabilitation (PR).
INTERVENTION
METHODS
Individualized PR intervention including breathing exercises, positioning, strengthening, functional training and ambulation twice a day for six days a week.
OUTCOME MEASURES
METHODS
One minute Sit to Stand Test (STST), Short Physical Performance Battery (SPPB), Fatigue Assessment Scale (FAS) and Post-COVID-19 Functional status Scale (PCFS).
RESULTS
RESULTS
Twenty-five participants (males-19, females-6) with a mean age of 54.25 ± 13.36 years were enrolled. Sixteen completed the two-point assessment after undergoing in-patient PR of mean duration 14.8 ± 9 days. PR led to a significant improvement in all functional outcomes i.e., STST (from 7.1 ± 4.3 repetitions to 14.2 ± 2.1 repetitions, SPPB (from 5 ± 2.8 to 9.4 ± 1.5), FAS (from 33.3 ± 10.8 to 25.8 ± 4.7) at the p value ≤0.001 and PCFS (from 3.6 ± 0.9 to 2.9 ± 1.2, p value ≤0.05).
CONCLUSION
CONCLUSIONS
Early initiation of PR for hospitalized patients with COVID-19 fibrosis was found to be safe, well-tolerated and feasible and may improve functional status. This article is protected by copyright. All rights reserved.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
This article is protected by copyright. All rights reserved.