Axin1's mystique in manipulating microbiome amidst colitis.

Animals Mice Axin Protein / genetics beta Catenin Colitis / chemically induced Gastrointestinal Microbiome Inflammation Microbiota Paneth Cells
Axin1 Axin2 Goblet cells Paneth cells Wnt beta-catenin colitis fecal microbiota transplantation inflammatory bowel disease microbiome

Journal

Gut microbes
ISSN: 1949-0984
Titre abrégé: Gut Microbes
Pays: United States
ID NLM: 101495343

Informations de publication

Date de publication:
Dec 2023
Historique:
medline: 29 11 2023
pubmed: 27 11 2023
entrez: 27 11 2023
Statut: ppublish

Résumé

Classically, Axin1 is considered a regulator of Wnt/β-catenin signaling. However, Axin1's roles in host-microbial interactions have been unknown. Our recent study has demonstrated that deletion of intestinal epithelial Axin1 in epithelial cells and Paneth cells protects the host against colitis by enhancing

Identifiants

DOI: 10.1080/19490976.2023.2286674 PMID: 38010886
pubmed: 38010886
doi: 10.1080/19490976.2023.2286674
doi:

Substances chimiques

Axin Protein 0
Axin1 protein, mouse 0
beta Catenin 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2286674

Auteurs

Shari Garrett (S)

Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.
Department of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA.

Monica C Asada (MC)

Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.

Jun Sun (J)

Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.
Department of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA.
UIC Cancer Center, University of Illinois Chicago, Chicago, IL, USA.
Medicine, Jesse Brown VA Medical Center, Chicago, IL, USA.
ORCID: 0000-0001-7465-3133

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Axin1's mystique in manipulating microbiome...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Axin1's mystique in manipulating microbiome...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Complexe de signalisation de l'axine › Axine › Axin1's mystique in manipulating microbiome...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › bêta-Caténine › Axin1's mystique in manipulating microbiome...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du côlon › Colite › Axin1's mystique in manipulating microbiome...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Axin1's mystique in manipulating microbiome...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Axin1's mystique in manipulating microbiome...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Axin1's mystique in manipulating microbiome...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules de Paneth › Axin1's mystique in manipulating microbiome...