Cranial vault suspension for basilar invagination in patients with open cranial sutures: technique and long-term follow-up. Illustrative case.

Hadju-Cheney syndrome basilar invagination occipitocervical fusion persistent cranial sutures

Journal

Journal of neurosurgery. Case lessons
ISSN: 2694-1902
Titre abrégé: J Neurosurg Case Lessons
Pays: United States
ID NLM: 9918227275606676

Informations de publication

Date de publication:
27 Nov 2023
Historique:
received: 25 09 2023
accepted: 12 10 2023
medline: 27 11 2023
pubmed: 27 11 2023
entrez: 27 11 2023
Statut: epublish

Résumé

Hajdu-Cheney syndrome (HCS) is an extremely rare genetic disorder characterized by severe osteoporosis, scoliosis, and persistent open cranial sutures (POCSs). Neurological complications include hydrocephalus, Chiari I malformations, and basilar invagination (BI). Surgical intervention in HCS is challenging due to severe osteoporosis, ligamentous laxity, POCSs, and extreme skeletal deformities. Herein, the authors present a case of BI repair in a patient with HCS and POCSs, requiring a novel technique of cranial vault suspension, with long-term follow-up. A 20-year-old female with HCS and progressive symptomatic BI, initially managed with posterior fossa decompression and occipital to cervical fusion, subsequently required cranial vault expansion due to symptomatic shifting of her cranium secondary to POCS. This custom construct provided long-term stabilization and neurological improvement over a follow-up duration of 9.5 years. A literature review performed revealed three other cases of surgical intervention for BI in patients with HCS and clinicopathological characteristics of each case was compared to the present illustrative case. POCSs in patients with BI complicate traditional surgical approaches, necessitating more invasive techniques to secure all mobile cranial parts for optimal outcomes. Using this cranial vault suspension and fusion technique results in lasting neurological improvement and construct stability.

Sections du résumé

BACKGROUND BACKGROUND
Hajdu-Cheney syndrome (HCS) is an extremely rare genetic disorder characterized by severe osteoporosis, scoliosis, and persistent open cranial sutures (POCSs). Neurological complications include hydrocephalus, Chiari I malformations, and basilar invagination (BI). Surgical intervention in HCS is challenging due to severe osteoporosis, ligamentous laxity, POCSs, and extreme skeletal deformities. Herein, the authors present a case of BI repair in a patient with HCS and POCSs, requiring a novel technique of cranial vault suspension, with long-term follow-up.
OBSERVATIONS METHODS
A 20-year-old female with HCS and progressive symptomatic BI, initially managed with posterior fossa decompression and occipital to cervical fusion, subsequently required cranial vault expansion due to symptomatic shifting of her cranium secondary to POCS. This custom construct provided long-term stabilization and neurological improvement over a follow-up duration of 9.5 years. A literature review performed revealed three other cases of surgical intervention for BI in patients with HCS and clinicopathological characteristics of each case was compared to the present illustrative case.
LESSONS CONCLUSIONS
POCSs in patients with BI complicate traditional surgical approaches, necessitating more invasive techniques to secure all mobile cranial parts for optimal outcomes. Using this cranial vault suspension and fusion technique results in lasting neurological improvement and construct stability.

Identifiants

pubmed: 38011698
doi: 10.3171/CASE23552
pii: CASE23552
pmc: PMC10684056
doi:
pii:

Types de publication

Journal Article

Langues

eng

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Auteurs

Christopher B Cutler (CB)

1Chicago Medical School, Rosalind Franklin University of Medicine and Science, Chicago, Illinois; and.

Daphne Li (D)

2Department of Neurosurgery, Division of Pediatric Neurosurgery, Advocate Lutheran General Hospital, Chicago, Illinois.

John R Ruge (JR)

2Department of Neurosurgery, Division of Pediatric Neurosurgery, Advocate Lutheran General Hospital, Chicago, Illinois.

Classifications MeSH