[Infections and male infertility].
Infections et infertilité masculine.
Epididymitis
Infections des glandes accessoires masculines
Infertilité masculine
Leucospermia
Leucospermie
Male accessory gland infections
Male infertility
Orchite
Orchitis
Prostatite
Prostatitis
Épididymite
Journal
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie
ISSN: 1166-7087
Titre abrégé: Prog Urol
Pays: France
ID NLM: 9307844
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
23
08
2023
revised:
08
09
2023
accepted:
12
09
2023
medline:
29
11
2023
pubmed:
28
11
2023
entrez:
28
11
2023
Statut:
ppublish
Résumé
The role of urogenital infections in male infertility has long been the subject of debate. A bibliographic search limited to English-language literature on human subjects published before 5/2023 resulted in the selection of 189 articles. Male infertility is often of multifactorial aetiology, and to optimise the prognosis it is important to manage all the factors that can be corrected, including infectious causes, which represent one of the most frequent aetiologies. The infectious agents involved in urogenital infections are most often bacterial or viral, and more rarely parasitic. They can infect the seminal tract, male accessory glands and/or testicles, and usually result in inflammation and increased oxidative stress. These infections reduce male fertility, in particular by altering spermogram parameters and increasing sperm DNA fragmentation. For these reasons, the search for a urogenital infection should be systematic, involving a careful history and clinical examination, ultrasound and systematic bacteriological tests guided by clinical findings. Aetiological treatment may be proposed depending on the picture and the germ involved. This review should help the urologist to establish an accurate diagnosis of the form and extent of the infection, and enable him to define an appropriate therapeutic strategy, tailored to the patient, in order to obtain the best chances of improving male fertility.
Sections du résumé
BACKGROUND
BACKGROUND
The role of urogenital infections in male infertility has long been the subject of debate.
METHODS
METHODS
A bibliographic search limited to English-language literature on human subjects published before 5/2023 resulted in the selection of 189 articles.
RESULTS
RESULTS
Male infertility is often of multifactorial aetiology, and to optimise the prognosis it is important to manage all the factors that can be corrected, including infectious causes, which represent one of the most frequent aetiologies. The infectious agents involved in urogenital infections are most often bacterial or viral, and more rarely parasitic. They can infect the seminal tract, male accessory glands and/or testicles, and usually result in inflammation and increased oxidative stress. These infections reduce male fertility, in particular by altering spermogram parameters and increasing sperm DNA fragmentation. For these reasons, the search for a urogenital infection should be systematic, involving a careful history and clinical examination, ultrasound and systematic bacteriological tests guided by clinical findings. Aetiological treatment may be proposed depending on the picture and the germ involved.
CONCLUSION
CONCLUSIONS
This review should help the urologist to establish an accurate diagnosis of the form and extent of the infection, and enable him to define an appropriate therapeutic strategy, tailored to the patient, in order to obtain the best chances of improving male fertility.
Identifiants
pubmed: 38012909
pii: S1166-7087(23)00217-8
doi: 10.1016/j.purol.2023.09.015
pii:
doi:
Types de publication
Review
English Abstract
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
636-652Informations de copyright
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