Early Serial Echocardiographic and Ultrasonographic Findings in Critically Ill Patients With COVID-19.
COVID-19
echocardiography
point-of-care ultrasound
strain
ultrasound
Journal
CHEST critical care
ISSN: 2949-7884
Titre abrégé: CHEST Crit Care
Pays: United States
ID NLM: 9918681585806676
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
medline:
28
11
2023
pubmed:
28
11
2023
entrez:
28
11
2023
Statut:
ppublish
Résumé
Cardiac function of critically ill patients with COVID-19 generally has been reported from clinically obtained data. Echocardiographic deformation imaging can identify ventricular dysfunction missed by traditional echocardiographic assessment. What is the prevalence of ventricular dysfunction and what are its implications for the natural history of critical COVID-19? This is a multicenter prospective cohort of critically ill patients with COVID-19. We performed serial echocardiography and lower extremity vascular ultrasound on hospitalization days 1, 3, and 8. We defined left ventricular (LV) dysfunction as the absolute value of longitudinal strain of < 17% or left ventricle ejection fraction (LVEF) of < 50%. Primary clinical outcome was inpatient survival. We enrolled 110 patients. Thirty-nine (35.5%) died before hospital discharge. LV dysfunction was present at admission in 38 patients (34.5%) and in 21 patients (36.2%) on day 8 ( Among patients with critical COVID-19, LV and RV dysfunction is common, frequently identified only through deformation imaging, and early (day 1) RV dysfunction may be associated with clinical outcome.
Sections du résumé
Background
UNASSIGNED
Cardiac function of critically ill patients with COVID-19 generally has been reported from clinically obtained data. Echocardiographic deformation imaging can identify ventricular dysfunction missed by traditional echocardiographic assessment.
Research Question
UNASSIGNED
What is the prevalence of ventricular dysfunction and what are its implications for the natural history of critical COVID-19?
Study Design and Methods
UNASSIGNED
This is a multicenter prospective cohort of critically ill patients with COVID-19. We performed serial echocardiography and lower extremity vascular ultrasound on hospitalization days 1, 3, and 8. We defined left ventricular (LV) dysfunction as the absolute value of longitudinal strain of < 17% or left ventricle ejection fraction (LVEF) of < 50%. Primary clinical outcome was inpatient survival.
Results
UNASSIGNED
We enrolled 110 patients. Thirty-nine (35.5%) died before hospital discharge. LV dysfunction was present at admission in 38 patients (34.5%) and in 21 patients (36.2%) on day 8 (
Interpretation
UNASSIGNED
Among patients with critical COVID-19, LV and RV dysfunction is common, frequently identified only through deformation imaging, and early (day 1) RV dysfunction may be associated with clinical outcome.
Identifiants
pubmed: 38014378
doi: 10.1016/j.chstcc.2023.100002
pii: S2949-7884(23)00002-3
pmc: PMC10030437
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100002Investigateurs
Nicole Calhoun
(N)
Judy Herrick
(J)
Eric Hoffman
(E)
Amanda McKillop
(A)
Kempapura Murthy
(K)
Michael Smith
(M)
Martha Zayed
(M)
Lesley De Souza
(L)
Ryan Kindle
(R)
Lori-Ann Kozikowski
(LA)
Scott Ouellette
(S)
Sherell Thornton-Thompson
(S)
Michael Bolstad
(M)
Robert Ciottone
(R)
Brianna Coviello
(B)
Arnaldo Devilla
(A)
Ana Grafals
(A)
Conor Higgins
(C)
Carlo Ottanelli
(C)
Kimberly Redman
(K)
Douglas Scaffidi
(D)
Alexander Weingart
(A)
Nathaniel Lewis
(N)
Samantha Olson
(S)
Kiran Ashok
(K)
Connery Brennan
(C)
Omar Mehkri
(O)
Megan Mitchell
(M)
Bryan Poynter
(B)
Nicholas Stanley
(N)
Caitlin Ten Lohuis
(CT)
Sean Caspers
(S)
Heidi Erikson
(H)
Audrey Hendrickson
(A)
Olivia Kaus
(O)
Ellen Maruggi
(E)
Tyler Scharber
(T)
Walker Tordsen
(W)
Valerie Aston
(V)
Robert Bowers
(R)
Jeffrey Jorgensen
(J)
Jennifer King
(J)
Harith Ali
(H)
Richard E Rothman
(RE)
Rahul Nair
(R)
Jen-Ting Chen
(JT)
Sarah Karow
(S)
Emily Robart
(E)
Paulo Nunes Maldonado
(PN)
Maryiam Khan
(M)
Preston So
(P)
Elizabeth Schwartz
(E)
Madison So
(M)
Michael Weigand
(M)
Andrea Luong
(A)
Jesus Martinez
(J)
Bao Huynh
(B)
Habiba Ibrahim
(H)
Cynthia Villanueva-Vargas
(C)
Haeun Jung
(H)
Juliana Villanueva-Vargas
(J)
Suha Quadri
(S)
Alexandra Jun Gordon
(AJ)
Joe Levitt
(J)
Cynthia Perez
(C)
Anita Visweswaran
(A)
Jonasel Roque
(J)
Adreanne Rivera
(A)
Trevor Frankel
(T)
Jennifer Goff
(J)
David Huynh
(D)
Kelly Jensen
(K)
Conner Driver
(C)
Ian Chambers
(I)
Paul Nassar
(P)
Lori Stout
(L)
Zita Sibenaller
(Z)
Alicia Walter
(A)
Jasmine Mares
(J)
Logan Olson
(L)
Bradley Clinansmith
(B)
Hayley Gershengorn
(H)
Carolina Rivas
(C)
E J McSpadden
(EJ)
Rachel Truscon
(R)
Anne Kaniclides
(A)
Lara Thomas
(L)
Ramsay Bielak
(R)
Weronika Damek Valvano
(WD)
Rebecca Fong
(R)
William J Fitzsimmons
(WJ)
Christopher Blair
(C)
Andrew Valesano
(A)
Leigh Baker
(L)
Julie Gilbert
(J)
Christine D Crider
(CD)
Kyle A Steinbock
(KA)
Thomas C Paulson
(TC)
Layla A Anderson
(LA)
Christy Kampe
(C)
Jakea Johnson
(J)
Laura L Short
(LL)
Lauren J Ezzell
(LJ)
Margaret E Whitsett
(ME)
Rendie E McHenry
(RE)
Samarian J Hargrave
(SJ)
Marica Blair
(M)
Jennifer L Luther
(JL)
Claudia Guevara Pulido
(CG)
Bryan Pm Peterson
(BP)
Mary LaRose
(M)
Leigha Landreth
(L)
Madeline Hicks
(M)
Lisa Parks
(L)
Jahnavi Bongu
(J)
David McDonald
(D)
Candice Cass
(C)
Sondra Seiler
(S)
David Park
(D)
Tiffany Hink
(T)
Meghan Wallace
(M)
Carey-Ann Burnham
(CA)
Olivia G Arter
(OG)
Informations de copyright
© 2023 The Authors.
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