Unlocking the Benefits of Fasting: A Review of Its Impact on Various Biological Systems and Human Health.

COVID-19. Fasting autophagy cancer cardiovascular system diabetes immune system nervous system obesity renin-angiotensin system

Journal

Current medicinal chemistry
ISSN: 1875-533X
Titre abrégé: Curr Med Chem
Pays: United Arab Emirates
ID NLM: 9440157

Informations de publication

Date de publication:
24 Nov 2023
Historique:
received: 02 08 2023
revised: 26 09 2023
accepted: 17 10 2023
medline: 29 11 2023
pubmed: 29 11 2023
entrez: 29 11 2023
Statut: aheadofprint

Résumé

Fasting has gained significant attention in recent years for its potential health benefits in various body systems. This review aims to comprehensively examine the effects of fasting on human health, specifically focusing on its impact on different body's physiological systems. The cardiovascular system plays a vital role in maintaining overall health, and fasting has shown promising effects in improving cardiovascular health markers such as blood pressure, cholesterol levels, and triglyceride levels. Additionally, fasting has been suggested to enhance insulin sensitivity, promote weight loss, and improve metabolic health, thus offering potential benefits to individuals with diabetes and metabolic disorders. Furthermore, fasting can boost immune function, reduce inflammation, enhance autophagy, and support the body's defense against infections, cancer, and autoimmune diseases. Fasting has also demonstrated a positive effect on the brain and nervous system. It has been associated with neuroprotective properties, improving cognitive function, and reducing the risk of neurodegenerative diseases, besides the ability of increasing the lifespan. Hence, understanding the potential advantages of fasting can provide valuable insights for individuals and healthcare professionals alike in promoting health and wellbeing. The data presented here may have significant implications for the development of therapeutic approaches and interventions using fasting as a potential preventive and therapeutic strategy.

Identifiants

pubmed: 38018193
pii: CMC-EPUB-136295
doi: 10.2174/0109298673275492231121062033
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Rawan Mackieh (R)

Department of Biology, Faculty of Sciences 3, Lebanese University, Campus Michel Slayman Ras Maska, Tripoli1352, Lebanon.

Nadia Al-Bakkar (N)

Faculty of Health Sciences, Beirut Arab University, Beirut Campus, P.O.Box 11 50 20, Riad El Solh, 11072809Beirut, Lebanon.

Milena Kfoury (M)

Department of Biology, Faculty of Sciences 3, Lebanese University, Campus Michel Slayman Ras Maska, Tripoli1352, Lebanon.

Nathalie Okdeh (N)

Department of Biology, Faculty of Sciences 3, Lebanese University, Campus Michel Slayman Ras Maska, Tripoli1352, Lebanon.

Hervé Pietra (H)

Association Esprit Jeûne & Fasting Spirit, 226, chemin du Pélican, Toulon83000, France.

Rabih Roufayel (R)

College of Engineering and Technology, American University of the Middle East, Kuwait.

Christian Legros (C)

Univ Angers, INSERM, CNRS, MITOVASC, Team 2 CarMe, SFR ICAT, 49000Angers, France.

Ziad Fajloun (Z)

Laboratory of Applied Biotechnology (LBA3B), Azm Center for Research in Biotechnology and Its Applications, EDST, Lebanese University, 1300Tripoli, Lebanon.

Jean-Marc Sabatier (JM)

Aix-Marseille Université, CNRS, INP, Inst Neurophysiopathol, 13385Marseille, France.

Classifications MeSH