High-Throughput Automatic Laser Printing Strategy toward Cost-effective Portable Integrated Urea Tele-Monitoring System.

electrochemical sensing kidney functional tele-monitoring laser printing laser-induced graphene urea sensor

Journal

Small methods
ISSN: 2366-9608
Titre abrégé: Small Methods
Pays: Germany
ID NLM: 101724536

Informations de publication

Date de publication:
Mar 2024
Historique:
revised: 21 10 2023
received: 03 09 2023
pubmed: 29 11 2023
medline: 29 11 2023
entrez: 29 11 2023
Statut: ppublish

Résumé

A portable sweat urea sensing system is a promising solution to satisfy the booming requirement of kidney function tele-monitoring. However, the complicated manufacturing route and the cumbersome electrochemical testing system still need to be improved to develop the urea point-of-care testing (POCT) and tele-monitoring devices. Here, a universal technical route based on a high-throughput automatic laser printing strategy for fabricating the portable integrated urea monitoring system is proposed. This integrated system includes a high-performance laser-printed urea sensing electrode, a planar three-electrode system, and a self-developed wireless mini-electrochemical workstation. A precursor donor layer is activated by laser scribing and in situ transferred into functional nanoparticles for the drop-on-demand printing of the urea sensing electrode. The obtained electrodes show high sensitivity, low detection limit, fast response time, high selectivity, good average recovery, and long-term stability for urea sensing. Additionally, a laser-induced graphene circuit-based miniature planar three-electrode system and a wireless mini-electrochemical workstation are designed for sensing data collection and transmitting, achieving real-time urea POCT and tele-monitoring. This scalable method provides a universal solution for high-throughput and ultra-fast fabrication of urea-sensing electrodes. The portable integrated urea monitoring system is a competitive option to achieve cost-effective POCT and tele-monitoring for kidney function.

Identifiants

pubmed: 38019189
doi: 10.1002/smtd.202301184
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2301184

Subventions

Organisme : Hong Kong Research Grants Council
ID : 25201620
Organisme : Hong Kong Research Grants Council
ID : C6001-22Y
Organisme : Hong Kong Innovation Technology Commission
ID : MHP/060/21
Organisme : State Key Laboratory of Advanced Displays and Optoelectronics Technologies
Organisme : Innovation and Technology Commission - Hong Kong
ID : ITC-CNERC14SC01

Informations de copyright

© 2023 The Authors. Small Methods published by Wiley-VCH GmbH.

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Auteurs

Yangyi Huang (Y)

Research Center on Smart Manufacturing, Division of Integrative Systems and Design, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.

Rongliang Yang (R)

Research Center on Smart Manufacturing, Division of Integrative Systems and Design, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.

Haosong Zhong (H)

Research Center on Smart Manufacturing, Division of Integrative Systems and Design, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.

Connie Kong Wai Lee (CKW)

Research Center on Smart Manufacturing, Division of Integrative Systems and Design, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.

Yexin Pan (Y)

Research Center on Smart Manufacturing, Division of Integrative Systems and Design, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.
Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.

Min Tan (M)

Research Center on Smart Manufacturing, Division of Integrative Systems and Design, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.

Yi Chen (Y)

Research Center on Smart Manufacturing, Division of Integrative Systems and Design, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.

Na Jiang (N)

Department of Nephrology, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 160, Pujian Road, Pudong District, Shanghai, 200127, P. R. China.

Mitch Guijun Li (MG)

Research Center on Smart Manufacturing, Division of Integrative Systems and Design, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.
Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Clear Water Bay, Kowloon, Hong Kong SAR, 999077, P. R. China.

Classifications MeSH