A novel peanut allergy immunotherapy: Plant-based enveloped Ara h 2 Bioparticles activate dendritic cells and polarize T cell responses to Th1.
Allergen immunotherapy
Dendritic cell
Microparticle
Peanut allergy
T cell
Journal
The World Allergy Organization journal
ISSN: 1939-4551
Titre abrégé: World Allergy Organ J
Pays: United States
ID NLM: 101481283
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
25
07
2023
revised:
19
09
2023
accepted:
17
10
2023
medline:
29
11
2023
pubmed:
29
11
2023
entrez:
29
11
2023
Statut:
epublish
Résumé
As the only market-authorized allergen immunotherapy (AIT) for peanut allergy is accompanied by a high risk of side effects and mainly induces robust desensitization without sustained efficacy, novel treatment options are required. Peanut-specific plant-derived Route and kinetics of Ara h 2 Ara h 2
Identifiants
pubmed: 38020282
doi: 10.1016/j.waojou.2023.100839
pii: S1939-4551(23)00099-6
pmc: PMC10679945
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100839Informations de copyright
© 2023 The Author(s).
Déclaration de conflit d'intérêts
C. Castenmiller received contract research funding and study material from Angany Inc. L.P. Vézina, G. Tropper and V. Gomord are a cofounder, board member, and respectively CSO, EVP and CIO of Angany Inc. R. Desgagnés, C. Martel, L. Auger, J. Roberge, B. Morel, V. Stordeur, and L. Mirande are employees of Angany Inc. R. van Ree received contract research funding and research material form Angany Inc. and besides received consulting fees and speaker's fees from Angany Inc. HAL Allergy BV, Citeq BV, ThermoFisher Scientific, Reacta Healthcare Ltd., Mission MightyMe, The Protein Brewery and AB Enzymes, and has stock options from Angany.
Références
Clin Exp Allergy. 2003 Sep;33(9):1198-208
pubmed: 12956739
J Allergy Clin Immunol. 2013 Jan;131(1):128-34.e1-3
pubmed: 23199605
Allergy. 2018 Jan;73(1):187-195
pubmed: 28675499
Lancet. 2019 Jun 1;393(10187):2222-2232
pubmed: 31030987
Gut. 2010 May;59(5):595-604
pubmed: 20427394
J Allergy Clin Immunol. 2011 Mar;127(3):640-6.e1
pubmed: 21281959
J Allergy Clin Immunol. 2022 Apr;149(4):1373-1382.e12
pubmed: 34653515
Clin Exp Allergy. 2004 Apr;34(4):583-90
pubmed: 15080811
J Clin Invest. 2003 Apr;111(7):1065-72
pubmed: 12671056
J Allergy Clin Immunol. 1996 Jun;97(6):1356-65
pubmed: 8648033
Immunotherapy. 2020 Aug;12(12):921-931
pubmed: 32611211
J Pharm Sci. 2022 Apr;111(4):1081-1091
pubmed: 35114209
Front Immunol. 2020 Nov 12;11:599083
pubmed: 33281825
J Allergy Clin Immunol. 2015 May;135(5):1249-56
pubmed: 25670011
Int J Nanomedicine. 2013;8:4553-62
pubmed: 24376349
Clin Exp Allergy. 2023 May;53(5):577-581
pubmed: 36779573
Eur J Pharm Biopharm. 2012 Oct;82(2):241-9
pubmed: 22782031
J Endotoxin Res. 2003;9(1):60-4
pubmed: 12691621
J Immunol. 2010 Feb 15;184(4):2194-203
pubmed: 20048125
Front Allergy. 2022 Aug 03;3:981126
pubmed: 35991310
Vaccine. 2010 Jul 12;28(31):5075-85
pubmed: 20478343
Clin Vaccine Immunol. 2010 Sep;17(9):1356-62
pubmed: 20631332
Curr Allergy Asthma Rep. 2020 Apr 20;20(5):14
pubmed: 32314071
J Exp Med. 2008 Sep 1;205(9):2139-49
pubmed: 18710932
Lancet. 2019 Oct 19;394(10207):1437-1449
pubmed: 31522849
J Allergy Clin Immunol. 2020 Apr;145(4):1240-1253.e3
pubmed: 31866435
Allergy. 2022 Oct;77(10):3124-3126
pubmed: 35916123
PLoS One. 2020 Dec 1;15(12):e0242867
pubmed: 33259521
Immunol Res. 2013 Mar;55(1-3):125-34
pubmed: 22948807
Clin Exp Allergy. 2021 Apr;51(4):527-535
pubmed: 33417257
Clin Rev Allergy Immunol. 2018 Oct;55(2):107-117
pubmed: 29488131
Clin Immunol. 2005 Jun;115(3):302-12
pubmed: 15893698
Allergy. 2022 Aug;77(8):2534-2548
pubmed: 35266148
Nat Rev Immunol. 2016 Dec;16(12):751-765
pubmed: 27795547
J Allergy Clin Immunol. 2014 Jan;133(1):121-9.e1-2
pubmed: 23870670
Pharm Res. 2007 Oct;24(10):1927-35
pubmed: 17541735
Clin Exp Allergy. 2006 Mar;36(3):261-72
pubmed: 16499636
Immunity. 2008 Sep 19;29(3):497-510
pubmed: 18789730
Int J Pharm. 2019 May 30;563:282-292
pubmed: 30902708
Lancet. 2022 Jan 22;399(10322):359-371
pubmed: 35065784
Clin Exp Allergy. 2004 Feb;34(2):315-21
pubmed: 14987314
Infect Immun. 2003 May;71(5):2498-507
pubmed: 12704121
Cureus. 2022 Feb 2;14(2):e21832
pubmed: 35291522
Vaccine. 2006 Mar 10;24(11):1847-57
pubmed: 16288821
Eur J Pharmacol. 2018 Jan 5;818:211-220
pubmed: 29079360
Clin Exp Allergy. 2008 Mar;38(3):520-8
pubmed: 18205856
Clin Exp Allergy. 2009 Jul;39(7):1099-108
pubmed: 19438581
J Immunol. 2002 Feb 15;168(4):1704-9
pubmed: 11823500
AAPS J. 2014 Sep;16(5):975-85
pubmed: 24981892
J Allergy Clin Immunol. 2012 Nov;130(5):1108-1116.e6
pubmed: 23021882
Sci Transl Med. 2017 Aug 2;9(401):
pubmed: 28768806
Clin Exp Allergy. 2019 Aug;49(8):1107-1115
pubmed: 31108010
Allergy. 2020 Jun;75(6):1337-1346
pubmed: 32034781
N Engl J Med. 2018 Nov 22;379(21):1991-2001
pubmed: 30449234
Allergy. 2020 Jun;75(6):1513-1516
pubmed: 31930521
Immunology. 2002 Jan;105(1):56-62
pubmed: 11849315
Semin Immunol. 2005 Aug;17(4):313-8
pubmed: 15955712
J Clin Invest. 2022 Jan 18;132(2):
pubmed: 34813505
Eur J Immunol. 2019 Mar;49(3):398-412
pubmed: 30620397
Allergy. 2005 May;60(5):678-84
pubmed: 15813815
Front Immunol. 2013 Jun 21;4:151
pubmed: 23801989
Int Arch Allergy Immunol. 2011;154(4):336-44
pubmed: 20975285
Allergy. 2001 Jun;56(6):498-505
pubmed: 11421893
J Exp Med. 2012 May 7;209(5):935-45
pubmed: 22547651
Allergy Asthma Immunol Res. 2016 May;8(3):257-63
pubmed: 26922936
Asian Pac J Allergy Immunol. 2020 Sep;38(3):139-149
pubmed: 32563231
Clin Exp Immunol. 2010 Jun;160(3):403-10
pubmed: 20345983
J Allergy Clin Immunol. 2020 Sep;146(3):621-630.e5
pubmed: 32298698
Int J Pharm. 2005 Jul 25;298(2):315-22
pubmed: 15961266