Cardioprotective effects of Moku-boi-to and its impact on AngII-induced cardiomyocyte hypertrophy.
Ca2+ homeostasis
Kampo medicine
ROS
angiotensin-receptor blocker
cardiomyocyte hypertrophy
cell volume regulation
mitochondria
mitochondria fission/fusion dynamics
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2023
2023
Historique:
received:
20
07
2023
accepted:
06
10
2023
medline:
29
11
2023
pubmed:
29
11
2023
entrez:
29
11
2023
Statut:
epublish
Résumé
Cardiomyocyte hypertrophy, induced by elevated levels of angiotensin II (AngII), plays a crucial role in cardiovascular diseases. Current therapeutic approaches aim to regress cardiac hypertrophy but have limited efficacy. Widely used Japanese Kampo medicines are highly safe and potential therapeutic agents. This study aims to explore the impact and mechanisms by which Moku-boi-to (MBT), a Japanese Kampo medicine, exerts its potential cardioprotective benefits against AngII-induced cardiomyocyte hypertrophy, bridging the knowledge gap and contributing to the development of novel therapeutic strategies. By evaluating the effects of six Japanese Kampo medicines with known cardiovascular efficiency on AngII-induced cardiomyocyte hypertrophy and cell death, we identified MBT as a promising candidate. MBT exhibited preventive effects against AngII-induced cardiomyocyte hypertrophy, cell death and demonstrated improvements in intracellular Ca
Identifiants
pubmed: 38020917
doi: 10.3389/fcell.2023.1264076
pii: 1264076
pmc: PMC10661958
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1264076Informations de copyright
Copyright © 2023 Tagashira, Abe, Sato-Numata, Aizawa, Hirasawa, Kure, Iwata and Numata.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Gen Physiol. 1998 Feb;111(2):181-3
pubmed: 9450937
Nat Rev Cardiol. 2016 Jun;13(6):368-78
pubmed: 26935038
Ann Transl Med. 2020 Nov;8(21):1396
pubmed: 33313141
Pflugers Arch. 2007 Jun;454(3):415-25
pubmed: 17285299
J Am Coll Cardiol. 1996 Mar 1;27(3):714-9
pubmed: 8606287
J Cardiol. 2022 Oct;80(4):306-312
pubmed: 34974939
J Neurochem. 2004 Aug;90(4):784-91
pubmed: 15287883
Basic Res Cardiol. 2014;109(6):451
pubmed: 25358972
Front Cardiovasc Med. 2022 Jan 18;8:822969
pubmed: 35118147
Cell Death Differ. 2014 Aug;21(8):1262-74
pubmed: 24786827
Circulation. 2010 May 11;121(18):2012-22
pubmed: 20421521
J Cell Sci. 2005 Jul 15;118(Pt 14):3049-59
pubmed: 15985469
Trends Pharmacol Sci. 2023 Jan;44(1):34-49
pubmed: 36396497
Circ Res. 1993 Jun;72(6):1245-54
pubmed: 8495553
Am J Chin Med. 2005;33(6):967-79
pubmed: 16355453
Mol Ther Nucleic Acids. 2021 Jun 24;25:416-443
pubmed: 34484866
Biomolecules. 2023 Feb 18;13(2):
pubmed: 36830764
Card Fail Rev. 2017 Apr;3(1):7-11
pubmed: 28785469
Life Sci. 1998;62(13):1139-46
pubmed: 9519794
Br J Pharmacol. 2023 Apr 24;:
pubmed: 37095602
Nat Rev Cardiol. 2017 Apr;14(4):238-250
pubmed: 28004807
Circulation. 2016 Aug 9;134(6):e32-69
pubmed: 27400984
J Cell Physiol. 2019 Aug;234(8):14198-14209
pubmed: 30618075
J Cell Mol Med. 2017 Dec;21(12):3394-3404
pubmed: 28643438
J Endocrinol. 2018 Mar;236(3):151-165
pubmed: 29371236
Am J Physiol. 1999 Sep;277(3):F437-46
pubmed: 10484527
Cell Calcium. 2019 Dec;84:102099
pubmed: 31614270
Am J Physiol Heart Circ Physiol. 2002 Apr;282(4):H1206-15
pubmed: 11893553
Phytomedicine. 2001 Sep;8(5):338-47
pubmed: 11695876
J Cardiol. 2019 Nov;74(5):412-417
pubmed: 31272834
Mol Biol Cell. 2001 Aug;12(8):2245-56
pubmed: 11514614
Mol Med Rep. 2012 Oct;6(4):811-4
pubmed: 22825027
J Cell Biochem. 2018 Nov;119(10):8290-8303
pubmed: 29923351
Commun Biol. 2021 May 20;4(1):599
pubmed: 34017036
Circ Res. 2013 Aug 30;113(6):709-24
pubmed: 23989714
EMBO Mol Med. 2010 Jul;2(7):247-57
pubmed: 20597104
Circ Res. 1993 Sep;73(3):413-23
pubmed: 8348686
Cell. 2009 Aug 21;138(4):628-44
pubmed: 19703392
Cell Res. 2014 Aug;24(8):977-93
pubmed: 25022898
Biomed Pharmacother. 2023 May;161:114533
pubmed: 36948131
J Pharmacol Sci. 2023 Feb;151(2):128-133
pubmed: 36707178
Pharm Biol. 2013 Dec;51(12):1538-44
pubmed: 23987742
Malar J. 2020 Jun 8;19(1):204
pubmed: 32513250
Antioxidants (Basel). 2023 Apr 04;12(4):
pubmed: 37107252
Biophys Rev. 2018 Aug;10(4):1097-1106
pubmed: 30019205
Int J Mol Sci. 2023 Mar 17;24(6):
pubmed: 36982862
Hypertension. 2020 Sep;76(3):827-838
pubmed: 32683902
Circulation. 2002 Mar 19;105(11):1380-6
pubmed: 11901052
Mol Endocrinol. 2006 May;20(5):953-70
pubmed: 16141358
J Cell Sci. 2014 Jun 15;127(Pt 12):2659-71
pubmed: 24777478
Curr Top Membr. 2019;83:205-283
pubmed: 31196606
Exp Mol Med. 2019 Dec 19;51(12):1-13
pubmed: 31857574
Mol Cell Biochem. 2019 Apr;454(1-2):33-44
pubmed: 30251118
Front Physiol. 2017 Jun 30;8:460
pubmed: 28713289
J Clin Invest. 2018 Aug 31;128(9):3716-3726
pubmed: 30124471
Ecotoxicol Environ Saf. 2022 Jul 15;240:113663
pubmed: 35642860
J Cardiol Cases. 2021 Jul 03;25(1):34-36
pubmed: 35024066
Cancer Res. 2010 Jan 15;70(2):440-6
pubmed: 20068163
Clin Case Rep. 2022 Jul 19;10(7):e6104
pubmed: 35865783
Fukushima J Med Sci. 2019 Aug 30;65(2):61-67
pubmed: 31434842
Physiology (Bethesda). 2006 Dec;21:380-7
pubmed: 17119150
Life Sci. 2017 Apr 15;175:1-10
pubmed: 28286226
Biochim Biophys Acta. 2013 Apr;1830(4):3082-94
pubmed: 23298811
Physiol Rep. 2018 Feb;6(4):
pubmed: 29479852
Evid Based Complement Alternat Med. 2010 Sep;7(3):341-349
pubmed: 20671770
Cell Physiol Biochem. 2019;53(6):961-981
pubmed: 31820856
Naunyn Schmiedebergs Arch Pharmacol. 2012 Aug;385(8):823-31
pubmed: 22569796
J Pharm Pharm Sci. 2015;18(3):547-50
pubmed: 26517140
J Mol Cell Cardiol. 2013 Feb;55:31-41
pubmed: 22982369
Nat Rev Cardiol. 2022 Nov;19(11):723-736
pubmed: 35523864
Nat Methods. 2012 Jul;9(7):671-5
pubmed: 22930834
Mol Neurobiol. 2014 Feb;49(1):222-33
pubmed: 23893294
Front Pharmacol. 2018 Mar 09;9:176
pubmed: 29593530
Life Sci. 2014 Jan 30;95(2):89-100
pubmed: 24373833
Int J Mol Sci. 2019 Sep 18;20(18):
pubmed: 31540546
Physiol Rep. 2015 Jun;3(6):
pubmed: 26109185
Nat Commun. 2022 Nov 4;13(1):6634
pubmed: 36333300