Regulatory T cells inhibit autoantigen-specific CD4
autoantigen-specific T cells
autoimmunity
immune regulation
lupus
regulatory T cells
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2023
2023
Historique:
received:
06
07
2023
accepted:
24
10
2023
medline:
1
12
2023
pubmed:
29
11
2023
entrez:
29
11
2023
Statut:
epublish
Résumé
Progressive loss of regulatory T cell (Treg)-mediated control over autoreactive effector T cells contributes to the development of systemic lupus erythematosus (SLE). Accordingly, we hypothesized that Treg may also have the capacity to suppress the activation of autoreactive CD4 To investigate whether Treg are involved in the control of autoreactive CD4 Both These results suggest that the activation and expansion of autoantigen-specific CD4
Identifiants
pubmed: 38022661
doi: 10.3389/fimmu.2023.1254176
pmc: PMC10667723
doi:
Substances chimiques
Autoantigens
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1254176Informations de copyright
Copyright © 2023 Rosenberger, Undeutsch, Akbarzadeh, Ohmes, Enghard, Riemekasten and Humrich.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Ann Rheum Dis. 2016 Jul;75(7):1407-15
pubmed: 26324847
Nat Med. 2005 Oct;11(10):1118-24
pubmed: 16186818
Kidney Int. 2021 Jan;99(1):238-246
pubmed: 32592813
Arthritis Rheum. 2001 Oct;44(10):2435-45
pubmed: 11665986
Expert Rev Clin Immunol. 2016 Nov;12(11):1153-1160
pubmed: 27283871
J Immunol. 2006 Aug 1;177(3):1451-9
pubmed: 16849451
Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):6020-4
pubmed: 1378619
Ann Rheum Dis. 2011 Dec;70(12):2176-83
pubmed: 21926188
Immunobiology. 2002 Dec;206(5):484-95
pubmed: 12607723
Nat Rev Rheumatol. 2016 Nov 22;12(12):716-730
pubmed: 27872476
Nat Immunol. 2010 Jan;11(1):7-13
pubmed: 20016504
Eur J Immunol. 2007 Sep;37(9):2370-7
pubmed: 17705136
Arthritis Rheum. 2003 Feb;48(2):475-85
pubmed: 12571858
Cell. 2008 May 30;133(5):775-87
pubmed: 18510923
Cells. 2019 Oct 11;8(10):
pubmed: 31614462
Scand J Rheumatol. 2006 May-Jun;35(3):209-16
pubmed: 16766368
Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):204-9
pubmed: 20018660
Immunity. 2009 May;30(5):636-45
pubmed: 19464986
Ann Rheum Dis. 2002 Sep;61(9):779-85
pubmed: 12176801
Arthritis Rheum. 2009 Jan;60(1):199-206
pubmed: 19116922
J Clin Invest. 1998 Aug 15;102(4):754-63
pubmed: 9710444