Diagnostic efficacy of C-X-C motif chemokine receptor 4-directed PET/CT in newly diagnosed head and neck squamous cell carcinoma - a head-to-head comparison with [

CXCR4 HSNCC PET PET/CT [68Ga]Ga-PentixaFor head and neck squamous cell carcinoma

Journal

American journal of nuclear medicine and molecular imaging
ISSN: 2160-8407
Titre abrégé: Am J Nucl Med Mol Imaging
Pays: United States
ID NLM: 101564121

Informations de publication

Date de publication:
2023
Historique:
received: 18 08 2023
accepted: 10 09 2023
medline: 29 11 2023
pubmed: 29 11 2023
entrez: 29 11 2023
Statut: epublish

Résumé

The aim of this study was to determine the read-out capabilities of the novel C-X-C motif chemokine receptor 4 (CXCR4)-targeting radiotracer [ 12 patients with histologically confirmed HNSCC were scheduled for [ On visual assessment, [ In HNSCC, [

Sections du résumé

BACKGROUND BACKGROUND
The aim of this study was to determine the read-out capabilities of the novel C-X-C motif chemokine receptor 4 (CXCR4)-targeting radiotracer [
MATERIAL AND METHODS METHODS
12 patients with histologically confirmed HNSCC were scheduled for [
RESULTS RESULTS
On visual assessment, [
CONCLUSIONS CONCLUSIONS
In HNSCC, [

Identifiants

pubmed: 38023816
pmc: PMC10656626

Types de publication

Journal Article

Langues

eng

Pagination

208-216

Informations de copyright

AJNMMI Copyright © 2023.

Déclaration de conflit d'intérêts

R.A.W. has received speaker honoraria from PentixaPharm and is involved in [68Ga]Ga-Pentixafor PET Imaging in PAN Cancer (FORPAN), sponsored and planned by PentixaPharm.

Références

AJR Am J Roentgenol. 2017 Aug;209(2):289-303
pubmed: 28731808
Laryngorhinootologie. 2000 Apr;79(4):201-6
pubmed: 10838683
Cancer. 2004 Dec 1;101(11):2641-9
pubmed: 15517576
N Engl J Med. 2016 Apr 14;374(15):1444-54
pubmed: 27007578
J Neurol Surg B Skull Base. 2019 Feb;80(1):18-22
pubmed: 30733896
Radiother Oncol. 2021 Feb;155:204-211
pubmed: 33252044
Nat Immunol. 2004 Sep;5(9):943-52
pubmed: 15300245
J Nucl Med. 2023 Jul;64(7):1009-1016
pubmed: 37290799
Theranostics. 2017 Apr 8;7(6):1589-1597
pubmed: 28529638
JAMA Otolaryngol Head Neck Surg. 2018 Nov 1;144(11):1037-1043
pubmed: 30242338
Adv Exp Med Biol. 2014;816:107-27
pubmed: 24818721
Eur J Cancer. 2017 Nov;85:6-14
pubmed: 28881249
Clin Nucl Med. 2023 Jan 1;48(1):35-42
pubmed: 36354691
Ann Nucl Med. 2013 Dec;27(10):880-5
pubmed: 23979967
Endocrine. 2022 Oct;78(1):169-176
pubmed: 35751778
J Nucl Med. 2023 Jan;64(1):34-39
pubmed: 35738903
Head Neck. 2019 Apr;41(4):1007-1015
pubmed: 30676682
Strahlenther Onkol. 2013 Mar;189(3):197-201
pubmed: 23329277
Head Neck. 2017 Sep;39(9):1733-1743
pubmed: 28650113
Annu Rev Immunol. 2022 Apr 26;40:413-442
pubmed: 35113731
Cancer Res. 1986 Aug;46(8 Suppl):4244s-4248s
pubmed: 3524805
J Nucl Med. 2022 Jun;63(6):875-881
pubmed: 34593594
Semin Nucl Med. 2021 Nov;51(6):633-645
pubmed: 34246448
Lancet. 2019 Nov 23;394(10212):1915-1928
pubmed: 31679945
JAMA Netw Open. 2021 Apr 1;4(4):e217083
pubmed: 33881529
J Nucl Med. 2022 Nov;63(11):1687-1692
pubmed: 35241482
Radiother Oncol. 2018 Jan;126(1):125-131
pubmed: 29061496
J Nucl Med. 2022 May;63(5):727-734
pubmed: 34385340
Oncotarget. 2017 Nov 20;8(68):112739-112747
pubmed: 29348861

Auteurs

Yingjun Zhi (Y)

Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, University Hospital Würzburg Würzburg 97080, Germany.

Rudolf A Werner (RA)

Department of Nuclear Medicine, University Hospital Würzburg Würzburg 97080, Germany.
Division of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine Baltimore, MD 21205, USA.

Andreas Schirbel (A)

Department of Nuclear Medicine, University Hospital Würzburg Würzburg 97080, Germany.

Takahiro Higuchi (T)

Department of Nuclear Medicine, University Hospital Würzburg Würzburg 97080, Germany.
Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Okayama 700-8530, Japan.

Andreas K Buck (AK)

Department of Nuclear Medicine, University Hospital Würzburg Würzburg 97080, Germany.

Aleksander Kosmala (A)

Department of Nuclear Medicine, University Hospital Würzburg Würzburg 97080, Germany.

Thorsten A Bley (TA)

Department of Diagnostic and Interventional Radiology, University Hospital Würzburg Würzburg 97080, Germany.

Rudolf Hagen (R)

Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, University Hospital Würzburg Würzburg 97080, Germany.

Stephan Hackenberg (S)

Department of Otorhinolaryngology - Head and Neck Surgery, RWTH Aachen University Aachen 52074, Germany.

Andreas Rosenwald (A)

Department of Pathology and Comprehensive Cancer Center Mainfranken, Julius-Maximilian University of Würzburg Würzburg 97080, Germany.

Agmal Scherzad (A)

Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, University Hospital Würzburg Würzburg 97080, Germany.

Elena Gerhard-Hartmann (E)

Department of Pathology and Comprehensive Cancer Center Mainfranken, Julius-Maximilian University of Würzburg Würzburg 97080, Germany.

Sebastian E Serfling (SE)

Department of Nuclear Medicine, University Hospital Würzburg Würzburg 97080, Germany.

Classifications MeSH