Tapia Syndrome and Severe Pain Induced by Occipital Bone Metastasis of Prostate Cancer.
3d conformal radiation therapy
palliative radiation therapy
prostate cancer
tapia syndrome
tapia's syndrome
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
accepted:
24
11
2023
medline:
29
11
2023
pubmed:
29
11
2023
entrez:
29
11
2023
Statut:
epublish
Résumé
Tapia syndrome is characterized by unilateral tongue paralysis, hoarseness, and dysphagia. It is often associated with issues in the lower cranial nerves and is rarely caused by malignant tumors. A 71-year-old Japanese male with prostate cancer and bone metastases experienced severe headaches, oral discomfort, dysphagia, and hoarseness for a month. Neurological examination revealed left-sided tongue atrophy and left vocal cord paralysis, suggesting problems with cranial nerves IX and XII. CT scans showed bone metastasis in the left occipital bone. Brain MRI showed no brain or meningeal metastasis, but neck MRI revealed a mass near the left hypoglossal canal. His prostate-specific antigen (PSA) level was 53.2 ng/mL. Based on these findings, we diagnosed him with occipital bone metastasis of prostate cancer with Tapia syndrome. We treated him with palliative radiation therapy (RT), delivering 30 Gy in 10 fractions over two weeks. We did not use drug treatment or chemotherapy due to side effects and the patient's preferences. After just one day of RT, his severe headache and oral discomfort significantly improved. By the end of the two-week treatment, his hoarseness had also improved, and he was able to eat. However, tongue atrophy had not improved three months after RT. We presented a unique case of palliative RT for occipital bone metastasis of prostate cancer with Tapia syndrome. Within two weeks, the patient's headache and dysphagia had greatly improved, although tongue atrophy remained partially unresolved after palliative RT.
Identifiants
pubmed: 38024075
doi: 10.7759/cureus.49327
pmc: PMC10668073
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e49327Informations de copyright
Copyright © 2023, Ishikawa et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
J Clin Oncol. 2018 Feb 10;36(5):446-453
pubmed: 29240541
J Med Case Rep. 2016 Jan 25;10:23
pubmed: 26809980
Acta Neurol Belg. 2015 Dec;115(4):533-7
pubmed: 26088745
Neurologia (Engl Ed). 2020 Oct;35(8):590-591
pubmed: 31103312
Laryngoscope. 2013 Oct;123(10):2423-7
pubmed: 24078360
Medicine (Baltimore). 2022 Sep 30;101(39):e30669
pubmed: 36181064
Oncology (Williston Park). 2014 Apr;28(4):306-12
pubmed: 24839802
J Neurosurg. 1980 May;52(5):730-2
pubmed: 7373407
Neurosurg Rev. 2023 Sep 14;46(1):244
pubmed: 37707587
Br J Anaesth. 2002 Jun;88(6):869-70
pubmed: 12173208
Anesth Analg. 2015 Jan;120(1):105-120
pubmed: 25625257
J Oral Maxillofac Surg. 2013 Oct;71(10):1665-9
pubmed: 23850042
Neurol India. 2015 Sep-Oct;63(5):782-3
pubmed: 26448244
Brain Dev. 2014 Jun;36(6):548-50
pubmed: 23958591
J Korean Neurosurg Soc. 2013 Nov;54(5):423-5
pubmed: 24379951