Eosinophilic granulomatosis with polyangiitis following flu guard influenza vaccination: A case report.
autoimmunity
eosinophilic granulomatosis with polyangiitis (EGPA)
influenza vaccine
vaccination
vasculitis
Journal
Clinical case reports
ISSN: 2050-0904
Titre abrégé: Clin Case Rep
Pays: England
ID NLM: 101620385
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
11
09
2023
revised:
17
10
2023
accepted:
30
10
2023
medline:
29
11
2023
pubmed:
29
11
2023
entrez:
29
11
2023
Statut:
epublish
Résumé
This case highlights a potential association between influenza vaccination and the development of eosinophilic granulomatosis with polyangiitis (EGPA), prompting the need for increased vigilance regarding vaccine-related autoimmune reactions. While causality remains unclear, clinicians should consider this possibility in patients presenting with EGPA-like symptoms shortly after vaccination. Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis characterized by tissue infiltration by eosinophils and hyper eosinophilia. We present a case of EGPA in a middle-aged man following influenza vaccination. The patient developed respiratory symptoms, skin lesions, joint pain, and neurological deficits. Diagnostic tests revealed eosinophilia, positive anti-neutrophil cytoplasmic antibodies, and elevated acute phase reactants. This report highlights a potential association between influenza vaccination and EGPA.
Identifiants
pubmed: 38028088
doi: 10.1002/ccr3.8217
pii: CCR38217
pmc: PMC10675098
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e8217Informations de copyright
© 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Déclaration de conflit d'intérêts
The authors declared that they have no conflict of interest.
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