Four pairs of neolignan enantiomers with distinctive isochroman moiety from the fruits of Crataegus pinnatifida and their protective activities against H
Crataegus pinnatifida
H(2)O(2)-Induced SH-SY5Y cells
Rosaceae
chiral resolution
neolignans
Journal
Phytochemistry
ISSN: 1873-3700
Titre abrégé: Phytochemistry
Pays: England
ID NLM: 0151434
Informations de publication
Date de publication:
27 Nov 2023
27 Nov 2023
Historique:
received:
11
08
2023
revised:
17
11
2023
accepted:
20
11
2023
pubmed:
30
11
2023
medline:
30
11
2023
entrez:
29
11
2023
Statut:
aheadofprint
Résumé
Four pairs of neolignan enantiomers (±)-1- (±)-4 with a distinctive isochroman moiety, including seven undescribed compounds, were isolated and identified from the fruits of Crataegus pinnatifida. Structural characterization of these compounds was established through comprehensive spectroscopic analyses, as well as quantum chemical calculations of ECD and NMR data. The preliminary bioassay displayed that compounds (+)-2 and (±)-3 exerted protective activities against H
Identifiants
pubmed: 38029952
pii: S0031-9422(23)00349-7
doi: 10.1016/j.phytochem.2023.113933
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113933Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. No potential conflict of interest was reported by the authors.