Polyarteritis Nodosa With Complications: A Diagnostic Challenge and Management Dilemma.
cutaneous polyarteritis nodosa
negative skin biopsy
polyarteritis nodosa
steroid-induced diabetes
vasculitis skin biopsy
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
accepted:
28
11
2023
medline:
30
11
2023
pubmed:
30
11
2023
entrez:
30
11
2023
Statut:
epublish
Résumé
Polyarteritis nodosa (PAN) is a rare autoimmune vasculitis characterized by the inflammation of medium-sized arteries throughout the body. This case report presents the clinical course of a 48-year-old female patient who experienced a complex diagnostic journey and complications during the management of PAN. The patient initially presented with dry skin, rash, and pruritus, which led to an extensive evaluation. Despite multiple visits and investigations, the definitive diagnosis of PAN was delayed. Eventually, the patient was diagnosed with PAN based on skin biopsy findings demonstrating vasculitis and inflammation of blood vessel walls. The treatment course was further complicated by the development of steroid-induced diabetes and recurrent vasculitis symptoms. Recurrence of symptoms, including rashes and neuropathy, necessitated adjustments in therapeutic interventions. This case highlights the challenges encountered in managing both PAN and its associated complications and emphasizes the importance of a multidisciplinary approach and improved patient compliance to optimize treatment outcomes.
Identifiants
pubmed: 38033446
doi: 10.7759/cureus.49677
pmc: PMC10686717
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e49677Informations de copyright
Copyright © 2023, Saghari et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Br J Dermatol. 2002 Apr;146(4):694-9
pubmed: 11966708
Arthritis Rheum. 2004 Feb 15;51(1):92-9
pubmed: 14872461
Dermatology. 2001;203(4):336-8
pubmed: 11752825
Autoimmun Rev. 2016 Jun;15(6):564-70
pubmed: 26884100
Indian Dermatol Online J. 2012 Jan;3(1):21-4
pubmed: 23130255
Arthritis Rheum. 2010 Feb;62(2):616-26
pubmed: 20112401
Arthritis Rheum. 2010 Apr;62(4):1186-97
pubmed: 20131268
Ann Vasc Dis. 2012;5(3):282-8
pubmed: 23555526