Genetic and molecular landscapes of the generalist phytopathogen Botrytis cinerea.
cross-kingdom sRNA
genetic diversity
grey mould
necrotrophy
Journal
Molecular plant pathology
ISSN: 1364-3703
Titre abrégé: Mol Plant Pathol
Pays: England
ID NLM: 100954969
Informations de publication
Date de publication:
01 Dec 2023
01 Dec 2023
Historique:
revised:
13
10
2023
received:
16
08
2023
accepted:
24
10
2023
medline:
1
12
2023
pubmed:
1
12
2023
entrez:
1
12
2023
Statut:
aheadofprint
Résumé
Botrytis cinerea Pers. Fr. (teleomorph: Botryotinia fuckeliana) is a necrotrophic fungal pathogen that attacks a wide range of plants. This updated pathogen profile explores the extensive genetic diversity of B. cinerea, highlights the progress in genome sequencing, and provides current knowledge of genetic and molecular mechanisms employed by the fungus to attack its hosts. In addition, we also discuss recent innovative strategies to combat B. cinerea. Kingdom: Fungi, phylum: Ascomycota, subphylum: Pezizomycotina, class: Leotiomycetes, order: Helotiales, family: Sclerotiniaceae, genus: Botrytis, species: cinerea. B. cinerea infects almost all of the plant groups (angiosperms, gymnosperms, pteridophytes, and bryophytes). To date, 1606 plant species have been identified as hosts of B. cinerea. This polyphagous necrotroph has extensive genetic diversity at all population levels shaped by climate, geography, and plant host variation. Genetic architecture of virulence and host specificity is polygenic using multiple weapons to target hosts, including secretory proteins, complex signal transduction pathways, metabolites, and mobile small RNA. Efforts to control B. cinerea, being a high-diversity generalist pathogen, are complicated. However, integrated disease management strategies that combine cultural practices, chemical and biological controls, and the use of appropriate crop varieties will lessen yield losses. Recently, studies conducted worldwide have explored the potential of small RNA as an efficient and environmentally friendly approach for combating grey mould. However, additional research is necessary, especially on risk assessment and regulatory frameworks, to fully harness the potential of this technology.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Agricultural Research Service
ID : 2019-05709
Organisme : Division of Integrative Organismal Systems
ID : IOS 2020754
Informations de copyright
© 2023 The Authors. Molecular Plant Pathology published by British Society for Plant Pathology and John Wiley & Sons Ltd.
Références
Abdel Wahab, H. (2015) Characterization of Egyptian Botrytis cinerea isolates from different host plants. Advances in Microbiology, 5, 177-189.
Abdollahi, A., Hassani, A., Ghosta, Y., Bernousi, I., Meshkatalsadat, M.H., Shabani, R. et al. (2012) Evaluation of essential oils for maintaining postharvest quality of Thompson Seedless table grape. Natural Products Research, 26, 77-83.
Acosta Morel, W., Marques-Costa, T.M., Santander-Gordón, D., Anta Fernández, F., Zabalgogeazcoa, I., Vázquez de Aldana, B.R. et al. (2018) Physiological and population genetic analysis of Botrytis field isolates from vineyards in Castilla y León, Spain. Plant Pathology, 68, 523-536.
Aktaruzzaman, M., Afroz, T., Hong, S.K., Kim, B.S. & Choi, H.W. (2022) First report of post-harvest gray mold on hyacinth bean (Lablab purpureus) caused by Botrytis cinerea in Korea. Plant Disease, 106, 1059.
Aktaruzzaman, M., Afroz, T., Kim, B.S. & Lee, Y.G. (2017) Occurrence of postharvest gray mold rot of sweet cherry due to Botrytis cinerea in Korea. Journal of Plant Diseases and Protection, 124, 93-96.
Albertini, C. & Leroux, P. (2004) A Botrytis cinerea putative 3-keto reductase gene (ERG27) that is homologous to the mammalian 17β-hydroxysteroid dehydrogenase type 7 gene (17β-HSD7). European Journal of Plant Pathology, 110, 723-733.
Albertini, C., Thebaud, G., Fournier, E. & Leroux, P. (2002) Eburicol 14α-demethylase gene (CYP51) polymorphism and speciation in Botrytis cinerea. Mycological Research, 106, 1171-1178.
Aliaga, C. (2013) Caracterizacion genetica y fenotipica de aislados chilenos de Botrytis cinerea Pers provenientes de Vitis vinifera L. cv. Thompson-Seedless con distinto nive de sensibilida [Thesis]. Facultad de Ciencias Agronómicas. Santiago, Chile: Universidad de Chile.
Almasaudi, N.M., Al-Qurashi, A.D., Elsayed, M.I. & Abo-Elyousr, K.A.M. (2022) Essential oils of oregano and cinnamon as an alternative method for control of gray mold disease of table grapes caused by Botrytis cinerea. Journal of Plant Pathology, 104, 317-328.
Alonso-Monge, R., Román, E., Arana, D.M., Pla, J. & Nombela, C. (2009) Fungi sensing environmental stress. Clinical Microbiology and Infection, 15, 17-19.
Amiri, A., Zuniga, A.I. & Peres, N.A. (2018) Prevalence of Botrytis cryptic species in strawberry nursery transplants and strawberry and blueberry commercial fields in the eastern United States. Plant Disease, 102, 398-404.
Amselem, J., Cuomo, C.A., van Kan, J.A.L., Viaud, M., Benito, E.P., Couloux, A. et al. (2011) Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea. PLoS Genetics, 7, e1002230.
An, B., Li, B., Li, H., Zhang, Z., Qin, G. & Tian, S. (2016) Aquaporin8 regulates cellular development and reactive oxygen species production, a critical component of virulence in Botrytis cinerea. New Phytologist, 209, 1668-1680.
Asadollahi, M., Fekete, E.B., Karaffa, L., Flipphi, M., Rnyasi, M.Ã., Esmaeili, M. et al. (2013) Comparison of Botrytis cinerea populations isolated from two open-field cultivated host plants. Microbiology Research, 168, 379-388.
Atwell, S., Corwin, J., Soltis, N. & Kliebenstein, D. (2018) Resequencing and association mapping of the generalist pathogen Botrytis cinerea. bioRxiv. https://doi.org/10.1101/489799
Atwell, S., Corwin, J.A., Soltis, N.E., Subedy, A., Denby, K.J. & Kliebenstein, D.J. (2015) Whole genome resequencing of Botrytis cinerea isolates identifies high levels of standing diversity. Frontiers in Microbiology, 6, 996.
Azevedo, D.M.Q., Guterres, D.C., Martins, S.D.S., Oliveira, W.M., Barreto, R.W. & Furtado, G.Q. (2020) First report of Botrytis cinerea causing gray mold on Sanchezia nobilis. Plant Disease, 104, 3080.
Backhouse, D. & Willetts, H.J. (1987) Development and structure of infection cushions of Botrytis cinerea. Transactions of the British Mycological Society, 89, 89-95.
Banno, S., Noguchi, R., Yamashita, K., Fukumori, F., Kimura, M., Yamaguchi, I. et al. (2007) Roles of putative His-to-Asp signaling modules HPT-1 and RRG-2, on viability and sensitivity to osmotic and oxidative stresses in Neurospora crassa. Current Genetics, 51, 197-208.
Bardin, M., Leyronas, C., Troulet, C. & Morris, C.E. (2018) Striking similarities between Botrytis cinerea from non-agricultural and from agricultural habitats. Frontiers in Plant Science, 9, 1820.
Beever, R.E. & Parkes, S.L. (1993) Mating behaviour and genetics of fungicide resistance of Botrytis cinerea in New Zealand. New Zealand Journal of Crop and Horticultural Science, 21, 303-310.
Ben Ahmed, D. & Hamada, W. (2005) Genetic diversity of some Tunisian Botrytis cinerea isolates using molecular markers. Phytopathologia Mediterranea, 44, 300-306.
Bi, K., Liang, Y., Mengiste, T. & Sharon, A. (2023) Killing softly: a roadmap of Botrytis cinerea pathogenicity. Trends in Plant Science, 28, 211-222.
Blanco-Ulate, B., Allen, G., Powell, A.L.T. & Cantu, D. (2013) Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of grape berries. Genome Announcements, 1, e00252-13.
Brown, N.A., Schrevens, S., Van Dijck, P. & Goldman, G.H. (2018) Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control. Nature Microbiology, 3, 402-414.
Campia, P. (2014) Sensitivity to fungicides and genetic structure of Botrytis cinerea populations isolated in Lombardy [Thesis]. Italy: Department of Agricultural and Environmental Sciences-Production, Landscape, Agroenergy, University of Milan.
Cao, X., Du, Y.L., Zhang, X.S., Li, H.Y., Guo, S.J., Hou, D. et al. (2020) First report of leaf blight disease on Lanzhou lily (Lilium davidii var. unicolor) caused by Botrytis cinerea in China. Plant Disease, 104, 291-292.
Caseys, C., Shi, G., Soltis, N., Gwinner, R., Corwin, J.A., Atwell, S. et al. (2021) Quantitative interactions: the disease outcome of Botrytis cinerea across the plant kingdom. G3: Genes, Genomes, Genetics, 11, jkab175.
Cettul, E., Rekab, D., Locci, R. & Firrao, G. (2008) Evolutionary analysis of endopolygalacturonase-encoding genes of Botrytis cinerea. Molecular Plant Pathology, 9, 675-685.
Chan, Z. & Tian, S. (2005) Interaction of antagonistic yeasts against postharvest pathogens of apple fruit and possible mode of action. Postharvest Biology and Technology, 36, 215-223.
Chen, J., Zhu, J.Z., Li, X.G., He, A.G., Xia, S.T. & Zhong, J. (2021) Botrytis cinerea causing gray mold of Polygonatum sibiricum (huang jing) in China. Crop Protection, 140, 105424.
Chen, L.J., Yin, Y.Y., Sun, S.K. & Sun, J. (2017) First report of a gray mold on Lilium cernuum Komar. leaves caused by Botrytis cinerea in Liaoning province of China. Journal of Plant Pathology, 99, 301.
Chen, T., Zhang, Z., Chen, Y., Li, B. & Tian, S. (2023) Botrytis cinerea. Current Biology, 33, R460-R462.
Chen, X.R., Huang, S.X., Wang, H., Zhang, Y. & Ji, Z.L. (2019) First report of Botrytis cinerea causing leaf spot of Chinese quince in China. Plant Disease, 103, 1028.
Chen, X.Y., Zhang, C.Q., Zhou, X.J., Zhu, L.Y. & He, X.C. (2020) First report of gray mold on jinxianlian (Anoectochilus roxburghii) caused by Botrytis cinerea in China. Plant Disease, 104, 1861-1862.
Cheung, N., Tian, L., Liu, X. & Li, X. (2020) The destructive fungal pathogen Botrytis cinerea-insights from genes studied with mutant analysis. Pathogens, 9, 923.
Choquer, M., Rascle, C., Gonçalves, I.R., de Vallée, A., Ribot, C., Loisel, E. et al. (2021) The infection cushion of Botrytis cinerea: a fungal ‘weapon’ of plant-biomass destruction. Environmental Microbiology, 23, 2293-2314.
Ciliberti, N., Fermaud, M., Roudet, J., Languasco, L. & Rossi, V. (2016) Environmental effects on the production of Botrytis cinerea conidia on different media, grape bunch trash, and mature berries. Australian Journal of Grape and Wine Research, 22, 262-270.
da Silva Ripardo-Filho, H., Coca Ruíz, V., Suárez, I., Moraga, J., Aleu, J. & Collado, I.G. (2023) From genes to molecules, secondary metabolism in Botrytis cinerea: new insights into anamorphic and teleomorphic stages. Plants, 12, 553.
Dalmais, B.R.R., Schumacher, J., Moraga, J., Le Pêcheur, P., Tudzynski, B., Collado, I.G. et al. (2011) The Botrytis cinerea phytotoxin botcinic acid requires two polyketide synthases for production and has a redundant role in virulence with botrydial. Molecular Plant Pathology, 12, 564-579.
De Coster, W., Weissensteiner, M.H. & Sedlazeck, F.J. (2021) Towards population-scale long-read sequencing. Nature Reviews Genetics, 22, 572-587.
Dean, R., Van Kan, J.A.L., Pretorius, Z.A., Hammond-Kosack, K.E., Di Pietro, A., Spanu, P.D. et al. (2012) The top 10 fungal pathogens in molecular plant pathology. Molecular Plant Pathology, 13, 414-430.
DeLong, J.A., Saito, S., Xiao, C.-L. & Naegele, R.P. (2020) Population genetics and fungicide resistance of Botrytis cinerea on Vitis and Prunus spp. in California. Phytopathology, 110, 694-702.
Derbyshire, M.C., Newman, T.E., Khentry, Y. & Owolabi Taiwo, A. (2022) The evolutionary and molecular features of the broad-host-range plant pathogen Sclerotinia sclerotiorum. Molecular Plant Pathology, 23, 1075-1090.
Diao, Y., Larsen, M., Kamvar, Z.N., Zhang, C., Li, S., Wang, W. et al. (2019) Genetic differentiation and clonal expansion of Chinese Botrytis cinerea populations from tomato and other crops in China. Phytopathology, 110, 428-439.
Dinh, S.Q., Joyce, D.C., Irving, D.E. & Wearing, A.H. (2011) Histology of waxflower (Chamelaucium spp.) flower infection by Botrytis cinerea. Plant Pathology, 60, 278-287.
Droby, S., Wisniewski, M., Macarisin, D. & Wilson, C. (2009) Twenty years of postharvest biocontrol research: is it time for a new paradigm? Postharvest Biology and Technology, 52, 137-145.
Duanis-Assaf, D., Galsurker, O., Davydov, O., Maurer, D., Feygenberg, O., Sagi, M. et al. (2022) Double-stranded RNA targeting fungal ergosterol biosynthesis pathway controls Botrytis cinerea and postharvest grey mould. Plant Biotechnology Journal, 20, 226-237.
Dugan, F. (1988) Cellular anatomy of penetration and infection of containerized western larch seedlings by Botrytis cinerea [Thesis]. Missoula, USA: University of Montana. Available from: https://scholarworks.umt.edu/etd/1755 [Accesed 24th October 2023].
Dumin, W., Seo, Y., Park, M., Park, J. & Back, C. (2020) First report of Botrytis cinerea causing grey mould disease of bush basil in Korea. New Disease Reports, 41, 33.
Elad, Y., Pertot, I., Cotes Prado, A.M. & Stewart, A. (2016) Plant hosts of Botrytis spp. In: Fillinger, S. & Elad, Y. (Eds.) Botrytis - the fungus, the pathogen and its management in agricultural systems. Switzerland: Springer International Publishing, pp. 413-486.
El-Baky, N.A. & Amara, A.A.A.F. (2021) Recent approaches towards control of fungal diseases in plants: an updated review. Journal of Fungi, 7, 900.
El-Defrawy, M.M.H. & Hesham, A.E.-L. (2020) G-protein-coupled receptors in fungi. In: Hesham, A.L., Upadhyay, R., Sharma, G., Manoharachary, C. & Gupta, V. (Eds.) Fungal biotechnology and bioengineering. Switzerland: Fungal Biology, pp. 37-126.
Emilda, D. (2015) Endophytic Botrytis on dandelion (Taraxacum officinale): truly endophytic or a latent pathogen waiting for a suitable host? [MSc thesis]. Wageningen, Netherlands: Wageningen University. Available from: https://edepot.wur.nl/351482 [Accessed 2th October 2023].
Esterio, M., Muñoz, G., Ramos, C., Cofré, G., Estévez, R., Salinas, A. et al. (2011) Characterization of Botrytis cinerea isolates present in Thompson Seedless table grapes in the Central Valley of Chile. Plant Disease, 95, 683-690.
Fan, X., Zhang, J., Yang, L., Wu, M., Chen, W. & Li, G. (2015) Development of PCR-based assays for detecting and differentiating three species of Botrytis infecting broad bean. Plant Disease, 99, 691-698.
Fekete, É., Fekete, E., Irinyi, L., Karaffa, L., Árnyasi, M., Asadollahi, M. et al. (2012) Genetic diversity of a Botrytis cinerea cryptic species complex in Hungary. Microbiology Research, 167, 283-291.
Fekrikohan, S., Atashi Khalilabad, A., Fotouhifar, K. & Sharifnabi, B. (2022) First report of Botrytis cinerea and Alternaria alternata on Pelargonium grandiflorum in Iran. Mycologia Iranica, 9, 105-115.
Feres, A.C., Barreto, R.W. & Lisboa, D.O. (2018) First report of grey mould caused by Botrytis cinerea on Hibiscus acetosella. Australasian Plant Disease Notes, 13, 42.
Fillinger, S. & Elad, Y. (2016) Botrytis - the fungus, the pathogen and its management in agricultural systems. Switzerland: Springer.
Fillinger, S. & Walker, A.-S. (2016) Chemical control and resistance management of botrytis diseases. In: Fillinger, S. & Elad, Y. (Eds.) Botrytis - the fungus, the pathogen and its management in agricultural systems. Switzerland: Springer International Publishing, pp. 189-216.
Fournier, E., Giraud, T., Albertini, C. & Brygoo, Y. (2005) Partition of the Botrytis cinerea complex in France using multiple gene genealogies. Mycologia, 97, 1251-1267.
Fournier, E., Gladieux, P. & Giraud, T. (2013) The ‘Dr Jekyll and Mr Hyde fungus’: noble rot versus gray mold symptoms of Botrytis cinerea on grapes. Evolutionary Applications, 6, 960-969.
Frandsen, R.J.N., Andersson, J.A., Kristensen, M.B. & Giese, H. (2008) Efficient four fragment cloning for the construction of vectors for targeted gene replacement in filamentous fungi. BMC Molecular Biology, 9, 70.
Freitas, E.F.S. & Pereira, O.L. (2022) First report of Botrytis cinerea causing basal leaf rot and defoliation on Maxillaria richii (Orchidaceae). Crop Protection, 159, 106034.
Frías, M., González, C. & Brito, N. (2011) BcSpl1, a cerato-platanin family protein, contributes to Botrytis cinerea virulence and elicits the hypersensitive response in the host. New Phytologist, 192, 483-495.
Fu, R., Ke, Y., Lu, D., Liu, Y., Gao, F. & Zhang, H. (2018) First report of gray mold caused by Botrytis cinerea on Paris polyphylla in China. Plant Disease, 102, 1447-1448.
Garibaldi, A., Bertetti, D., Ortega, S.F. & Gullino, M.L. (2016) First report of botrytis blight caused by Botrytis cinerea on fruit-scented sage in Italy. Journal of Plant Pathology, 98, 179.
Garibaldi, A., Bertetti, D., Tabone, G., Luongo, I. & Gullino, M.L. (2022) First report of botrytis blight caused by Botrytis cinerea on Helleborus niger in Italy. Plant Disease, 106, 333.
Garibaldi, A., Gilardi, G., Matic, S. & Gullino, M.L. (2017) First report of Botrytis cinerea on Hydrangea paniculata in Italy. Plant Disease, 101, 1043.
Giraud, T., Fortini, D., Levis, C., Lamarque, C., Leroux, P., LoBuglio, K. et al. (1999) Two sibling species of the Botrytis cinerea complex, transposa and vacuma, are found in sympatry on numerous host plants. Phytopathology, 89, 967-973.
Giraud, T., Fortini, D., Levis, C., Leroux, P. & Brygoo, Y. (1997) RFLP markers show genetic recombination in Botryotinia fuckeliana (Botrytis cinerea) and transposable elements reveal two sympatric species. Molecular Biology and Evolution, 14, 1177-1185.
Goodfellow, S., Zhang, D., Wang, M.-B. & Zhang, R. (2019) Bacterium-mediated RNA interference: potential application in plant protection. Plants, 8, 572.
Govrin, E.M. & Levine, A. (2000) The hypersensitive response facilitates plant infection by the necrotrophic pathogen Botrytis cinerea. Current Biology, 10, 751-757.
Gregory, P.H. (1949) Studies on Sclerotinia and Botrytis: II. De Bary's description and specimens of Peziza fuckeliana. Transactions of the British Mycological Society, 32, 1-10.
Gronover, C.S., Kasulke, D., Tudzynski, P. & Tudzynski, B. (2001) The role of G protein alpha subunits in the infection process of the gray mold fungus Botrytis cinerea. Molecular Plant-Microbe Interactions, 14, 1293-1302.
Guo, J., Chen, J., Hu, Z., Zhong, J. & Zhu, J.Z. (2021) First report of leaf spot caused by Botrytis cinerea on Cardamine hupingshanensis in China. Plant Disease, 105, 3749.
Hahn, M. & Scalliet, G. (2021) One cut to change them all: CRISPR/Cas, a groundbreaking tool for genome editing in Botrytis cinerea and other fungal plant pathogens. Phytopathology, 111, 474-477.
Hall, A., Parsonage, D., Horita, D., Karplus, P.A., Poole, L.B. & Barbar, E. (2009) Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds. Biochemistry, 48, 5984-5993.
Hayashi, K., Schoonbeek, H.-j. & De Waard, M.A. (2002) Bcmfs1, a novel major facilitator superfamily transporter from Botrytis cinerea, provides tolerance towards the natural toxic compounds camptothecin and cercosporin and towards fungicides. Applied and Environmental Microbiology, 68, 4996-5004.
He, B., Cai, Q., Weiberg, A., Li, W., Cheng, A.-P., Ouyang, S. et al. (2023) Botrytis cinerea small RNAs are associated with tomato AGO1 and silence tomato defense-related target genes supporting cross-kingdom RNAi. bioRxiv, 2022.2012. 2030.522274.
Heller, J., Ruhnke, N., Espino, J.J., Massaroli, M., Collado, I.G. & Tudzynski, P. (2012) The mitogen-activated protein kinase BcSak1 of Botrytis cinerea is required for pathogenic development and has broad regulatory functions beyond stress response. Molecular Plant--Microbe Interactions, 25, 802-816.
Heller, J. & Tudzynski, P. (2011) Reactive oxygen species in phytopathogenic fungi: signaling, development, and disease. Annual Review of Phytopathology, 49, 369-390.
Hermosa, R., Viterbo, A., Chet, I. & Monte, E. (2012) Plant-beneficial effects of Trichoderma and of its genes. Microbiology, 158, 17-25.
Hu, M.-J., Dowling, M.E. & Schnabel, G. (2018) Genotypic and phenotypic variations in Botrytis spp. isolates from single strawberry flowers. Plant Disease, 102, 179-184.
Hua, L., Yong, C., Zhanquan, Z., Boqiang, L., Guozheng, Q. & Shiping, T. (2018) Pathogenic mechanisms and control strategies of Botrytis cinerea causing post-harvest decay in fruits and vegetables. Food Quality and Safety, 2, 111-119.
Isenegger, A.D., Ades, P.K., Ford, R. & Taylor, P.W.J. (2008) Status of the Botrytis cinerea species complex and microsatellite analysis of transposon types in South Asia and Australia. Fungal Diversity, 29, 17-26.
Ish-Shalom, S., Gafni, A., Lichter, A. & Levy, M. (2011) Transformation of Botrytis cinerea by direct hyphal blasting or by wound-mediated transformation of sclerotia. BMC Microbiology, 11, 266.
Isidoro-Gonzales, M.L., Ortega-Acosta, C., Sánchez-Ruiz, F.J., Ortega-Acosta, S.Á., Terrones-Salgado, J., Palemón-Alberto, F. et al. (2023) First report of Botrytis cinerea causing postharvest mold gray on rose apple (Syzygium jambos) in Mexico. Journal of Plant Pathology, 105, 1201-1202.
Jeon, C.W., Kim, D.R., Gang, G.H., Kim, B.B., Kim, N.H., Nam, S.Y. et al. (2020) First report of gray mold disease on endangered species Cypripedium japonicum. Mycobiology, 48, 423-426.
Jin, M.J., Yang, C.D., Wei, L.J., Cui, L.X., Wang, Y.D. & Osei, R. (2022) First report of Botrytis cinerea causing gray mold on Astragalus membranaceus in China. Plant Disease, 106, 1520.
Johnston, P.R., Hoksbergen, K., Park, D. & Beever, R.E. (2013) Genetic diversity of Botrytis in New Zealand vineyards and the significance of its seasonal and regional variation. Plant Pathology, 63, 888-898.
Kecskeméti, E., Brathuhn, A., Kogel, K.-H., Berkelmann-Löhnertz, B. & Reineke, A. (2014) Presence of transposons and mycoviruses in Botrytis cinerea isolates collected from a German grapevine growing region. Journal of Phytopathology, 162, 582-595.
Kim, J.-O., Shin, J.-H., Gumilang, A., Chung, K., Choi, K.Y. & Kim, K.S. (2016) Effectiveness of different classes of fungicides on Botrytis cinerea causing gray mold on fruit and vegetables. Plant Pathology Journal, 32, 570-574.
Klotz, L.-O. (2002) Oxidant-induced signaling: effects of peroxynitrite and singlet oxygen. Biological Chemistry, 383, 443-456.
Kozhar, O., Larsen, M.M., Grünwald, N.J. & Peever, T.L. (2020) Fungal evolution in anthropogenic environments: Botrytis cinerea populations infecting small fruit hosts in the Pacific northwest rapidly adapt to human-induced selection pressures. Applied and Environmental Microbiology, 86, e02908-02919.
Kumari, S., Tayal, P., Sharma, E. & Kapoor, R. (2014) Analyses of genetic and pathogenic variability among Botrytis cinerea isolates. Microbiology Research, 169, 862-872.
Kuroyanagi, T., Bulasag, A.S., Fukushima, K., Ashida, A., Suzuki, T., Tanaka, A. et al. (2022) Botrytis cinerea identifies host plants via the recognition of antifungal capsidiol to induce expression of a specific detoxification gene. PNAS Nexus, 1, pgac274.
Kuzmanovska, B., Rusevski, R., Jankuloski, L., Jankulovska, M., Ivic, D. & Bandzo, K. (2012) Phenotypic and genetic characterization of Botrytis cinerea isolates from tomato. Genetika, 44, 633-647.
Lecompte, F., Nicot, P.C., Ripoll, J., Abro, M.A., Raimbault, A.K., Lopez-Lauri, F. et al. (2017) Reduced susceptibility of tomato stem to the necrotrophic fungus Botrytis cinerea is associated with a specific adjustment of fructose content in the host sugar pool. Annals of Botany, 119, 931-943.
Leisen, T., Werner, J., Pattar, P., Safari, N., Ymeri, E., Sommer, F. et al. (2022) Multiple knockout mutants reveal a high redundancy of phytotoxic compounds contributing to necrotrophic pathogenesis of Botrytis cinerea. PLoS Pathogens, 18, e1010367.
Leyronas, C., Bryone, F., Duffaud, M., Troulet, C. & Nicot, P.C. (2014) Assessing host specialization of Botrytis cinerea on lettuce and tomato by genotypic and phenotypic characterization. Plant Pathology, 64, 119-127.
Li, H., Tian, S. & Qin, G. (2019) NADPH oxidase is crucial for the cellular redox homeostasis in fungal pathogen Botrytis cinerea. Molecular Plant-Microbe Interactions, 32, 1508-1516.
Li, J.S., Zhang, M.M., Yang, Z.F. & Li, C. (2022) Botrytis cinerea causes flower gray mold in Gastrodia elata in China. Crop Protection, 155, 105923.
Li, J.X., Yuan, W.J., Chen, H., Chen, X.A., Miao, Y.H. & Liu, D.H. (2023) First report of Botrytis cinerea causing gray mold on Prunella vulgaris in Hubei Province, China. Plant Disease, 107, 1947.
Li, L., Wright, S.J., Krystofova, S., Park, G. & Borkovich, K.A. (2007) Heterotrimeric G protein signaling in filamentous fungi. Annual Review of Microbiology, 61, 423-452.
Li, Y., Sun, S., Du, C., Xu, C., Zhang, J., Duan, C. et al. (2016) A new disease of mung bean caused by Botrytis cinerea. Crop Protection, 85, 52-56.
Lin, Z., Wu, J., Jamieson, P.A. & Zhang, C. (2019) Alternative oxidase is involved in the pathogenicity, development, and oxygen stress response of Botrytis cinerea. Phytopathology, 109, 1679-1688.
Liu, W., Leroux, P. & Fillinger, S. (2008) The HOG1-like MAP kinase Sak1 of Botrytis cinerea is negatively regulated by the upstream histidine kinase Bos1 and is not involved in dicarboximide-and phenylpyrrole-resistance. Fungal Genetics and Biology, 45, 1062-1074.
Liu, Y., Liu, J.K., Li, G.H., Zhang, M.Z., Zhang, Y.Y., Wang, Y.Y. et al. (2019) A novel Botrytis cinerea-specific gene BcHBF1 enhances virulence of the grey mould fungus via promoting host penetration and invasive hyphal development. Molecular Plant Pathology, 20, 731-747.
Liu, Y., Xue, L.H. & Li, C.J. (2017) First report of gray mold caused by Botrytis cinerea on Rumex acetosa in China. Plant Disease, 101, 1050-1051.
López-Cruz, J., Óscar, C.S., Emma, F.C., Pilar, G.A. & Carmen, G.B. (2017) Absence of Cu-Zn superoxide dismutase BCSOD1 reduces Botrytis cinerea virulence in Arabidopsis and tomato plants, revealing interplay among reactive oxygen species, callose and signalling pathways. Molecular Plant Pathology, 18, 16-31.
Lorenzini, M. & Zapparoli, G. (2014) An isolate morphologically and phylogenetically distinct from Botrytis cinerea obtained from withered grapes possibly represents a new species of Botrytis. Plant Pathology, 63, 1326-1335.
Ma, D. & Li, R. (2013) Current understanding of HOG-MAPK pathway in Aspergillus fumigatus. Mycopathologia, 175, 13-23.
Ma, Z. & Michailides, T.J. (2005) Genetic structure of Botrytis cinerea populations from different host plants in California. Plant Disease, 89, 1083-1089.
Makris, G., Nikoloudakis, N., Samaras, A., Karaoglanidis, G.S. & Kanetis, L.I. (2022) Under pressure: a comparative study of Botrytis cinerea populations from conventional and organic farms in Cyprus and Greece. Phytopathology, 112, 2236-2247.
Martinez, F., Blancard, D., Lecomte, P., Levis, C., Dubos, B. & Fermaud, M. (2003) Phenotypic differences between vacuma and transposa subpopulations of Botrytis cinerea. European Journal of Plant Pathology, 109, 479-488.
Martinez, F., Dubos, B. & Fermaud, M. (2005) The role of saprotrophy and virulence in the population dynamics of Botrytis cinerea in vineyards. Phytopathology, 95, 692-700.
Martínez-Soto, D. & Ruiz-Herrera, J. (2017) Functional analysis of the MAPK pathways in fungi. Revista Iberoamericana de Micologia, 34, 192-202.
Mercier, A., Carpentier, F., Duplaix, C., Auger, A., Pradier, J.M., Viaud, M. et al. (2019) The polyphagous plant pathogenic fungus Botrytis cinerea encompasses host-specialized and generalist populations. Environmental Microbiology, 21, 4808-4821.
Mercier, A., Simon, A., Lapalu, N., Giraud, T., Bardin, M., Walker, A.-S. et al. (2021) Population genomics reveals molecular determinants of specialization to tomato in the polyphagous fungal pathogen Botrytis cinerea in France. Phytopathology, 111, 2355-2366.
Möller, M. & Stukenbrock, E.H. (2017) Evolution and genome architecture in fungal plant pathogens. Nature Reviews Microbiology, 15, 756-771.
Moparthi, S., Parikh, L.P., Gunnink Troth, E.E. & Burrows, M.E. (2023) Identification and prevalence of seedborne botrytis spp. in dry pea, lentil, and chickpea in Montana. Plant Disease, 107, 382-392.
Muñoz, G. & Campos, F. (2013) Genetic characterization of Botrytis cinerea isolates collected from pine and eucalyptus nurseries in Bio-Bio region, Chile. Forest Pathology, 43, 509-512.
Muñoz, G., Campos, F., Salgado, D., Galdames, R., Gilchrist, L., Chahin, G. et al. (2016) Molecular identification of Botrytis cinerea, Botrytis paeoniae and Botrytis pseudocinerea associated with gray mould disease in peonies (Paeonia lactiflora Pall.) in southern Chile. Revista Iberoamericana de Micología, 33, 43-47.
Muñoz, G., Hinrichsen, P., Brygoo, Y. & Giraud, T. (2002) Genetic characterisation of Botrytis cinerea populations in Chile. Mycological Research, 106, 594-601.
Naegele, R.P., DeLong, J., Alzohairy, S.A., Saito, S., Abdelsamad, N. & Miles, T.D. (2021) Population genetic analyses of Botrytis cinerea isolates from Michigan vineyards using a high-throughput marker system approach. Frontiers in Microbiology, 12, 660874.
Navazio, L., Baldan, B., Moscatiello, R., Zuppini, A., Woo, S.L., Mariani, P. et al. (2007) Calcium-mediated perception and defense responses activated in plant cells by metabolite mixtures secreted by the biocontrol fungus Trichoderma atroviride. BMC Plant Biology, 7, 41.
Nelson, K.J., Knutson, S.T., Soito, L., Klomsiri, C., Poole, L.B. & Fetrow, J.S. (2011) Analysis of the peroxiredoxin family: using active-site structure and sequence information for global classification and residue analysis. Proteins: Structure, Function, and Bioinformatics, 79, 947-964.
Nelson, K.J. & Parsonage, D. (2011) Measurement of peroxiredoxin activity. Current Protocols in Toxicology, 49, 7-10.
Orozco-Mosqueda, M.D.C., Kumar, A., Fadiji, A.E., Babalola, O.O., Puopolo, G. & Santoyo, G. (2023) Agroecological management of the grey mould fungus Botrytis cinerea by plant growth-promoting bacteria. Plants, 12, 637.
Patel, R., Van Kan, J., Bailey, A. & Foster, G. (2008) RNA-mediated gene silencing of superoxide dismutase (bcsod1) in Botrytis cinerea. Phytopathology, 98, 1334-1339.
Paula, M.G., Barreto, R.W. & Ferreira, B.W. (2018) First report of Botrytis cinerea causing gray mould on Neomarica longifolia. Australasian Plant Disease Notes, 13, 21.
Pedras, M.S.C., Hossain, S. & Snitynsky, R.B. (2011) Detoxification of cruciferous phytoalexins in Botrytis cinerea: spontaneous dimerization of a camalexin metabolite. Phytochemistry, 72, 199-206.
Pei, Y.-G., Tao, Q.-J., Zheng, X.-J., Li, Y., Sun, X.-F., Li, Z.F. et al. (2019) Phenotypic and genetic characterization of Botrytis cinerea population from kiwifruit in Sichuan Province, China. Plant Disease, 103, 748-758.
Perlin, M.H., Andrews, J. & San Toh, S. (2014) Essential letters in the fungal alphabet: ABC and MFS transporters and their roles in survival and pathogenicity. Advances in Genetics, 85, 201-253.
Plaza, V., Bustamante, C., Silva-Moreno, E. & Castillo, L. (2018) First report of Botrytis cinerea causing gray mold disease on the endemic plant Echinopsis coquimbana in the Coquimbo region, Chile. Plant Disease, 102, 1448-1449.
Plesken, C., Pattar, P., Reiss, B., Noor, Z.N., Zhang, L., Klug, K. et al. (2021) Genetic diversity of Botrytis cinerea revealed by multilocus sequencing, and identification of B. cinerea populations showing genetic isolation and distinct host adaptation. Frontiers in Plant Science, 12, 663027.
Polat, İ., Baysal, Ö., Mercati, F., Gümrükcü, E., Sülü, G., Kitapcı, A. et al. (2018) Characterization of Botrytis cinerea isolates collected on pepper in southern Turkey by using molecular markers, fungicide resistance genes and virulence assay. Infection, Genetics and Evolution, 60, 151-159.
Porquier, A. (2019) Botcinic acid biosynthesis in Botrytis cinerea relies on a subtelomeric gene cluster surrounded by relics of transposons and is regulated by the Zn2Cys6 transcription factor BcBoa13. Current Genetics, 65, 965-980.
Porquier, A., Morgant, G., Moraga, J., Dalmais, B., Luyten, I., Simon, A. et al. (2016) The botrydial biosynthetic gene cluster of Botrytis cinerea displays a bipartite genomic structure and is positively regulated by the putative Zn(II)2Cys6 transcription factor BcBot6. Fungal Genetics and Biology, 96, 33-46.
Porquier, A., Tisserant, C., Salinas, F., Glassl, C., Wange, L., Enard, W. et al. (2021) Retrotransposons as pathogenicity factors of the plant pathogenic fungus Botrytis cinerea. Genome Biology, 22, 225.
Qiao, L., Lan, C., Capriotti, L., Ah-Fong, A., Nino Sanchez, J., Hamby, R. et al. (2021) Spray-induced gene silencing for disease control is dependent on the efficiency of pathogen RNA uptake. Plant Biotechnology Journal, 19, 1756-1768.
Rajaguru, B. & Shaw, M.W. (2010) Genetic differentiation between hosts and locations in populations of latent Botrytis cinerea in southern England. Plant Pathology, 59, 1081-1090.
Reboledo, G., Agorio, A.D., Vignale, L., Batista-García, R.A. & Ponce De León, I. (2021) Transcriptional profiling reveals conserved and species-specific plant defense responses during the interaction of Physcomitrium patens with Botrytis cinerea. Plant Molecular Biology, 107, 365-385.
Ren, W., Liu, N., Yang, Y., Yang, Q., Chen, C. & Gao, Q. (2019) The sensor proteins BcSho1 and BcSln1 are involved in, though not essential to, vegetative differentiation, pathogenicity and osmotic stress tolerance in Botrytis cinerea. Frontiers in Microbiology, 10, 328.
Richards, J.K., Xiao, C.-L. & Jurick, W.M. (2021) Botrytis spp: a contemporary perspective and synthesis of recent scientific developments of a widespread genus that threatens global food security. Phytopathology, 111, 432-436.
Rolke, Y., Liu, S., Quidde, T., Williamson, B., Schouten, A., Weltring, K.M. et al. (2004) Functional analysis of H2O2-generating systems in Botrytis cinerea: the major Cu-Zn-superoxide dismutase (BCSOD1) contributes to virulence on French bean, whereas a glucose oxidase (BCGOD1) is dispensable. Molecular Plant Pathology, 5, 17-27.
Rolland, S., Jobic, C., Fèvre, M. & Bruel, C. (2003) Agrobacterium-mediated transformation of Botrytis cinerea, simple purification of monokaryotic transformants and rapid conidia-based identification of the transfer-DNA host genomic DNA flanking sequences. Current Genetics, 44, 164-171.
Román Ramos, A.E. (2013) Caracterización genética y fenotípica de aislados chilenos de Botrytis cinerea de diferente grado de sensibilidad a Boscalid. [Thesis]. Facultad de Ciencias Agronómicas. Santiago, Chile: Universidad de Chile.
Romanazzi, G., Feliziani, E. & Sivakumar, D. (2018) Chitosan, a biopolymer with triple action on postharvest decay of fruit and vegetables: eliciting, antimicrobial and film-forming properties. Frontiers in Microbiology, 9, 2745.
Romanazzi, G., Smilanick, J.L., Feliziani, E. & Droby, S. (2016) Integrated management of postharvest gray mold on fruit crops. Postharvest Biology and Technology, 113, 69-76.
Rossi, F.R., Gárriz, A., Marina, M., Romero, F.M., Gonzalez, M.E., Collado, I.G. et al. (2011) The sesquiterpene botrydial produced by Botrytis cinerea induces the hypersensitive response on plant tissues and its action is modulated by salicylic acid and jasmonic acid signaling. Molecular Plant-Microbe Interactions, 24, 888-896.
Schamber, A., Leroch, M., Diwo, J., Mendgen, K. & Hahn, M. (2010) The role of mitogen-activated protein (MAP) kinase signalling components and the Ste12 transcription factor in germination and pathogenicity of Botrytis cinerea. Molecular Plant Pathology, 11, 105-119.
Schumacher, J. (2012) Tools for Botrytis cinerea: new expression vectors make the gray mold fungus more accessible to cell biology approaches. Fungal Genetics and Biology, 49, 483-497.
Schumacher, J. (2017) How light affects the life of Botrytis. Fungal Genetics and Biology, 106, 26-41.
Schumacher, J., de Larrinoa, I.F. & Tudzynski, B. (2008) Calcineurin-responsive zinc finger transcription factor CRZ1 of Botrytis cinerea is required for growth, development, and full virulence on bean plants. Eukaryotic Cell, 7, 584-601.
Schumacher, J., Kokkelink, L., Huesmann, C., Jimenez-Teja, D., Collado, I.G., Barakat, R. et al. (2008) The cAMP-dependent signaling pathway and its role in conidial germination, growth, and virulence of the gray mold Botrytis cinerea. Molecular Plant-Microbe Interactions, 21, 1443-1459.
Schumacher, J., Viaud, M., Simon, A. & Tudzynski, B. (2008) The Gα subunit BCG1, the phospholipase C (BcPLC1) and the calcineurin phosphatase co-ordinately regulate gene expression in the grey mould fungus Botrytis cinerea. Molecular Microbiology, 67, 1027-1050.
Seaver, L.C. & Imlay, J.A. (2001) Hydrogen peroxide fluxes and compartmentalization inside growing Escherichia coli. Journal of Bacteriology, 183, 7182-7189.
Segmüller, N., Ellendorf, U., Tudzynski, B. & Tudzynski, P. (2007) BcSAK1, a stress-activated mitogen-activated protein kinase, is involved in vegetative differentiation and pathogenicity in Botrytis cinerea. Eukaryotic Cell, 6, 211-221.
Segmüller, N., Kokkelink, L., Giesbert, S., Odinius, D., van Kan, J. & Tudzynski, P. (2008) NADPH oxidases are involved in differentiation and pathogenicity in Botrytis cinerea. Molecular Plant-Microbe Interactions, 21, 808-819.
Shlezinger, N., Minz, A., Gur, Y., Hatam, I., Dagdas, Y.F., Talbot, N.J. et al. (2011) Anti-apoptotic machinery protects the necrotrophic fungus Botrytis cinerea from host-induced apoptotic-like cell death during plant infection. PLoS Pathogens, 7, e1002185.
Siegmund, U., Marschall, R. & Tudzynski, P. (2015) BcNoxD, a putative ER protein, is a new component of the NADPH oxidase complex in Botrytis cinerea. Molecular Microbiology, 95, 988-1005.
Siewers, V., Viaud, M., Jimenez-Teja, D., Collado, I.G., Gronover, C.S., Pradier, J.-M. et al. (2005) Functional analysis of the cytochrome P450 monooxygenase gene bcbot1 of Botrytis cinerea indicates that botrydial is a strain-specific virulence factor. Molecular Plant-Microbe Interactions, 18, 602-612.
Silva, M., Corrêa, F., Pinho, D., Pereira, O. & Furtado, G. (2016) First report of Botrytis cinerea on Miconia cinnamomifolia. Australasian Plant Disease Notes, 11, 1-2.
Silva, M., Lisboa, D., Pinho, D., Pereira, O. & Furtado, G. (2016) First report of gray mold caused by Botrytis cinerea on Joannesia princeps in a forest nursery in Brazil. Plant Disease, 100, 523.
Simon, A., Mercier, A., Gladieux, P., Poinssot, B., Walker, A.-S. & Viaud, M. (2022) Botrytis cinerea strains infecting grapevine and tomato display contrasted repertoires of accessory chromosomes, transposons and small RNAs. Peer Community Journal, 2, e83.
Sivakumar, D. & Bautista-Baños, S. (2014) A review on the use of essential oils for postharvest decay control and maintenance of fruit quality during storage. Crop Protection, 64, 27-37.
Soltis, N.E., Atwell, S., Shi, G., Fordyce, R., Gwinner, R., Gao, D. et al. (2019) Crop domestication and pathogen virulence: interactions of tomato and botrytis genetic diversity. The Plant Cell, 31, 502-519.
Song, J.W., Shi, Y.X., Xie, X.W., Chai, A.L. & Li, B.J. (2017) First report of grey mould on water dropwort (Oenanthe javanica DC.) caused by Botrytis cinerea. Canadian Journal of Plant Pathology, 39, 235-240.
Staats, M. & van Kan, J.A.L. (2012) Genome update of Botrytis cinerea strains B05.10 and T4. Eukaryotic Cell, 11, 1413-1414.
Stefanato, F.L., Abou-Mansour, E., Buchala, A., Kretschmer, M., Mosbach, A., Hahn, M. et al. (2009) The ABC transporter BcatrB from Botrytis cinerea exports camalexin and is a virulence factor on Arabidopsis thaliana. The Plant Journal, 58, 499-510.
Stincone, A., Prigione, A., Cramer, T., Wamelink, M.M., Campbell, K., Cheung, E. et al. (2015) The return of metabolism: biochemistry and physiology of the pentose phosphate pathway. Biological Reviews, 90, 927-963.
Sun, J., Sun, C.-H., Chang, H.-W., Yang, S., Liu, Y., Zhang, M.-Z. et al. (2021) Cyclophilin BcCyp2 regulates infection-related development to facilitate virulence of the gray mold fungus Botrytis cinerea. International Journal of Molecular Sciences, 22, 1694.
Takemoto, D., Tanaka, A. & Scott, B. (2007) NADPH oxidases in fungi: diverse roles of reactive oxygen species in fungal cellular differentiation. Fungal Genetics and Biology, 44, 1065-1076.
Tanović, B., Delibašić, G., Milivojević, J. & Nikolić, M. (2009) Characterization of Botrytis cinerea isolates from small fruits and grapevine in Serbia. Archives of Biological Sciences, 61, 419-429.
Tanović, B., Hrustić, J., Mihajlović, M., Grahovac, M. & Delibašić, G. (2014) Botrytis cinerea in raspberry in Serbia I: morphological and molecular characterization. Pesticidi i Fitomedicina, 29, 237-247.
Testempasis, S., Puckett, R.D., Michailides, T.J. & Karaoglanidis, G.S. (2020) Genetic structure and fungicide resistance profile of botrytis spp. populations causing postharvest gray mold of pomegranate fruit in Greece and California. Postharvest Biology and Technology, 170, 111319.
Tian, S.P., Yao, H.J., Deng, X., Xu, X.B., Qin, G.Z. & Chan, Z.L. (2007) Characterization and expression of β-1,3-glucanase genes in jujube fruit induced by the microbial biocontrol agent Cryptococcus laurentii. Phytopathology, 97, 260-268.
Toffolatti, S.L., Maddalena, G., Marcianò, D., Passera, A. & Quaglino, F. (2020) A molecular epidemiology study reveals the presence of identical genotypes on grapevines and ground cover weeds and the existence of separate genetic groups in a Botrytis cinerea population. Plant Pathology, 69, 1695-1707.
Topolovec-Pintarić, S., Miličević, T. & Cvjetković, B. (2004) Genetic diversity and dynamic of pyrimethanil-resistant phenotype in population of Botrytis cinerea Pers: Fr. in one wine-growing area in Croatia. Journal of Plant Diseases and Protection, 111, 451-460.
Törün, B. & Biyik, H.H. (2022) Frequency of transposable elements and fungicide resistance in Botrytis cinerea Pers. populations on strawberries from Aydin and Mersin provinces in Türkiye. Sigma Journal of Engineering and Natural Sciences, 40, 281-291.
Tripathi, P. & Dubey, N. (2004) Exploitation of natural products as an alternative strategy to control postharvest fungal rotting of fruit and vegetables. Postharvest Biology and Technology, 32, 235-245.
Uslu, V.V., Bassler, A., Krczal, G. & Wassenegger, M. (2020) High-pressure-sprayed double stranded RNA does not induce RNA interference of a reporter gene. Frontiers in Plant Science, 11, 534391.
Vaczy, K.Z., Sandor, E., Karaffa, L., Fekete, E., Fekete, E., Arnyasi, M. et al. (2008) Sexual recombination in the Botrytis cinerea populations in Hungarian vineyards. Phytopathology, 98, 1312-1319.
Van Kan, J., Van't Klooster, J., Wagemakers, C., Dees, D. & Van der Vlugt-Bergmans, C. (1997) Cutinase A of Botrytis cinerea is expressed, but not essential, during penetration of gerbera and tomato. Molecular Plant-Microbe Interactions, 10, 30-38.
Van Kan, J.A.L., Stassen, J.H.M., Mosbach, A., Van Der Lee, T.A.J., Faino, L., Farmer, A.D. et al. (2017) A gapless genome sequence of the fungus Botrytis cinerea. Molecular Plant Pathology, 18, 75-89.
Vatsa-Portugal, P., Walker, A.-S.S., Jacquens, L., Clément, C., Barka, E.A. & Vaillant-Gaveau, N. (2014) Inflorescences vs leaves: a distinct modulation of carbon metabolism process during Botrytis infection. Physiologia Plantarum, 154, 162-177.
Vela-Corcía, D., Aditya Srivastava, D., Dafa-Berger, A., Rotem, N., Barda, O. & Levy, M. (2019) MFS transporter from Botrytis cinerea provides tolerance to glucosinolate-breakdown products and is required for pathogenicity. Nature Communications, 10, 2886.
Veloso, J. & van Kan, J.A.L. (2018) Many shades of grey in Botrytis-host plant interactions. Trends in Plant Science, 23, 613-622.
Vercesi, A., Toffolatti, S.L., Venturini, G., Campia, P. & Scagnelli, S. (2014) Characterization of Botrytis cinerea populations associated with treated and untreated cv. Moscato vineyards. Phytopathologia Mediterranea, 53, 108-123.
Viaud, M., Fillinger, S., Liu, W., Polepalli, J.S., Le Pêcheur, P., Kunduru, A.R. et al. (2006) A class III histidine kinase acts as a novel virulence factor in Botrytis cinerea. Molecular Plant-Microbe Interactions, 19, 1042-1050.
Viefhues, A., Heller, J., Temme, N. & Tudzynski, P. (2014) Redox systems in Botrytis cinerea: impact on development and virulence. Molecular Plant-Microbe Interactions, 27, 858-874.
Viefhues, A., Schlathoelter, I., Simon, A., Viaud, M. & Tudzynski, P. (2015) Unraveling the function of the response regulator BcSkn7 in the stress signaling network of Botrytis cinerea. Eukaryotic Cell, 14, 636-651.
Wagih, E.E., Wahab, H.A., Shehata, M.R.A., Fahmy, M.M. & Gaber, M.A. (2020) Molecular and pathological variability associated with transposable elements of Botrytis cinerea isolates infecting grape and strawberry in Egypt. International Journal of Phytopathology, 8, 37-51.
Walker, A.S. (2013) Diversité et adaptation aux fongicides des populations de Botrytis cinerea, agent de la pourriture grise. [Thesis]. Sciences Agricoles. Paris: Université Paris Sud.
Walker, A.-S.S., Gladieux, P., Decognet, V., Fermaud, M., Confais, J., Roudet, J. et al. (2014) Population structure and temporal maintenance of the multihost fungal pathogen Botrytis cinerea: causes and implications for disease management. Environmental Microbiology, 17, 1261-1274.
Wang, M., Weiberg, A., Dellota, E., Jr., Yamane, D. & Jin, H. (2017) Botrytis small RNA Bc-siR37 suppresses plant defense genes by cross-kingdom RNAi. RNA Biology, 14, 421-428.
Wang, Y., Jin, L., Zhu, T.T. & Zeng, C.Y. (2017) First report of Botrytis cinerea on Anemarrhena asphodeloides and Aster tataricus. Journal of Plant Diseases and Protection, 124, 241-243.
Wang, Y., Jing, L., Zhu, T. & Chen, H. (2017) First report of gray mold caused by Botrytis cinerea on two medicinal plants, Angelica sinensis and Glycyrrhiza uralensis, in China. Plant Disease, 101, 245.
Wang, Y., Yang, L. & Bai, Q.R. (2017) First report of Botrytis cinerea causing gray mold of Peperomia ferreyrae in Jilin Province, China. Plant Disease, 101, 250.
Weiberg, A., Wang, M., Lin, F.-M., Zhao, H., Zhang, Z., Kaloshian, I. et al. (2013) Fungal small RNAs suppress plant immunity by hijacking host RNA interference pathways. Science, 342, 118-123.
Wessels, B.A., Lamprecht, S.C., Linde, C.C., Fourie, P.H. & Mostert, L. (2013) Characterization of the genetic variation and fungicide resistance in Botrytis cinerea populations on rooibos seedlings in the Western Cape of South Africa. European Journal of Plant Pathology, 136, 407-417.
Wessels, B.A., Linde, C.C., Fourie, P.H. & Mostert, L. (2016) Genetic population structure and fungicide resistance of Botrytis cinerea in pear orchards in the Western Cape of South Africa. Plant Pathology, 65, 1473-1483.
Westrick, N.M., Smith, D.L. & Kabbage, M. (2021) Disarming the host: detoxification of plant defense compounds during fungal necrotrophy. Frontiers in Plant Science, 12, 651716.
Williamson, B., Tudzynski, B., Tudzynski, P. & Van Kan, J.A.L. (2007) Botrytis cinerea: the cause of grey mould disease. Molecular Plant Pathology, 8, 561-580.
Xue, L., Li, C., Liu, Y., Wu, W., Zhang, L., Huang, X. et al. (2016) First report of Botryotinia fuckeliana causing gray mold of annual ryegrass (Lolium multiflorum) in China. Plant Disease, 100, 1236.
Xue, L.H., Liu, Y., Wu, W.X., Zhang, L., Huang, X.Q. & Li, C.J. (2017) First report of Botrytis cinerea causing gray mold of Aconitum carmichaelii in China. Plant Disease, 101, 248.
Yaakoub, H., Sanchez, N.S., Ongay-Larios, L., Courdavault, V., Calenda, A., Bouchara, J.-P. et al. (2022) The high osmolarity glycerol (HOG) pathway in fungi. Critical Reviews in Microbiology, 48, 657-695.
Yan, L., Yang, Q., Jiang, J., Michailides, T.J. & Ma, Z. (2011) Involvement of a putative response regulator Brrg-1 in the regulation of sporulation, sensitivity to fungicides, and osmotic stress in Botrytis cinerea. Applied Microbiology and Biotechnology, 90, 215-226.
Yan, L., Yang, Q., Sundin, G.W., Li, H. & Ma, Z. (2010) The mitogen-activated protein kinase kinase BOS5 is involved in regulating vegetative differentiation and virulence in Botrytis cinerea. Fungal Genetics and Biology, 47, 753-760.
Yang, C.L., Chen, Q., Liu, Y.G. & Xu, X.L. (2020) First report of gray mold on Aquilaria sinensis caused by Botrytis cinerea in China. Plant Disease, 104, 292-293.
Yang, C.L., Liu, Y.G. & Xu, X.L. (2020a) First report of Botrytis cinerea infecting Fagraea ceilanica in China. Plant Disease, 104, 285.
Yang, C.L., Liu, Y.G. & Xu, X.L. (2020b) First report of gray mold caused by Botrytis cinerea on Magnolia × alba in China. Plant Disease, 104, 994-995.
Yang, H.-H., Yang, S.L., Peng, K.-C., Lo, C.-T. & Liu, S.-Y. (2009) Induced proteome of Trichoderma harzianum by Botrytis cinerea. Mycological Research, 113, 924-932.
Yang, Q., Yin, D., Yin, Y., Cao, Y. & Ma, Z. (2015) The response regulator BcSkn7 is required for vegetative differentiation and adaptation to oxidative and osmotic stresses in Botrytis cinerea. Molecular Plant Pathology, 16, 276-287.
Yang, R., Li, N., Zhou, Z. & Li, G. (2020) Characterization of the populations of Botrytis cinerea infecting plastic tunnel-grown strawberry and tomato in Hubei Province of China. Plant Disease, 105, 1890-1897.
Yang, Y., Yang, X., Dong, Y. & Qiu, D. (2018) The Botrytis cinerea xylanase BcXyl1 modulates plant immunity. Frontiers in Microbiology, 9, 2535.
You, J.M., Gu, J., Yuan, Q.F., Guo, X.L., Gao, L.X., Duan, Y.Y. et al. (2020) Botrytis cinerea causing grey mould on Epimedium brevicornum maxim in China. Canadian Journal of Plant Pathology, 42, 228-234.
Zhang, W., Corwin, J.A., Copeland, D.H., Feusier, J., Eshbaugh, R., Cook, D.E. et al. (2019) Plant-necrotroph co-transcriptome networks illuminate a metabolic battlefield. eLife, 8, e44279.
Zhang, Y., Li, X., Shen, F., Xu, H., Li, Y. & Liu, D. (2018) Characterization of Botrytis cinerea isolates from grape vineyards in China. Plant Disease, 102, 40-48.
Zhu, W., Dong, H., Xu, R., You, J., Yan, D.-Z., Xiong, C. et al. (2023) Botrytis cinerea BcCDI1 protein triggers both plant cell death and immune response. Frontiers in Plant Science, 14, 1136463.