Effectiveness of SplashGuard Caregivers prototype in reducing the risk of aerosol transmission in intensive care unit rooms of SARS-CoV-2 patients: a prospective and simulation study.

3D simulation COVID-19 airborne virus transmission intensive care unit

Journal

The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166

Informations de publication

Date de publication:
29 Nov 2023
Historique:
received: 06 09 2023
revised: 17 11 2023
accepted: 20 11 2023
medline: 2 12 2023
pubmed: 2 12 2023
entrez: 1 12 2023
Statut: aheadofprint

Résumé

The contagiousness of SARS-CoV-2 is known to be linked to the emission of bioaerosols. Thus, clinical patient manipulation called "aerosol-generating procedures" (AGP) could increase the risk of healthcare worker (HCW) developing an infection. To investigate the impact of an aerosol protection box, the SplashGuard Caregivers (SGGC) with suction system, by direct analysis of the presence of viral particles after an AGP and by using the Computational Fluid Dynamics (CFD) simulation method. Prospective observational study including the HCW in charge of SARS-CoV-2 patient admitted to an intensive care unit (ICU). Room patients analysed were divided in: SGCG present and absent. Virus detection was performed through direct analysis and a CFD model to simulate the movement dynamics of airborne particles produced by a patient's respiratory activities. Of the 67 analyses performed, 3 samples were qPCR positive: one out of 33 analyses in the SCCG group (3%) and 2 out of 34 analyses in the no SGCG group (:5.9%). CFD simulations showed that: (1) the addition of a SGCG with reduced gaps could decrease the number of emitted particles remaining airborne within the room by up to 70%; (2) positioning the HCW airway in the opposite direction to the main airflow would also reduce its exposure. This study document the presence of SARS-CoV-2 on caregivers in negative pressure ICU room of an infected patient with or without the use of SGCG. The simulation provides help in the design improvement of SGCG and the caregivers positioning in the room.

Sections du résumé

BACKGROUND BACKGROUND
The contagiousness of SARS-CoV-2 is known to be linked to the emission of bioaerosols. Thus, clinical patient manipulation called "aerosol-generating procedures" (AGP) could increase the risk of healthcare worker (HCW) developing an infection.
AIM OBJECTIVE
To investigate the impact of an aerosol protection box, the SplashGuard Caregivers (SGGC) with suction system, by direct analysis of the presence of viral particles after an AGP and by using the Computational Fluid Dynamics (CFD) simulation method.
METHODS METHODS
Prospective observational study including the HCW in charge of SARS-CoV-2 patient admitted to an intensive care unit (ICU). Room patients analysed were divided in: SGCG present and absent. Virus detection was performed through direct analysis and a CFD model to simulate the movement dynamics of airborne particles produced by a patient's respiratory activities.
FINDINGS RESULTS
Of the 67 analyses performed, 3 samples were qPCR positive: one out of 33 analyses in the SCCG group (3%) and 2 out of 34 analyses in the no SGCG group (:5.9%). CFD simulations showed that: (1) the addition of a SGCG with reduced gaps could decrease the number of emitted particles remaining airborne within the room by up to 70%; (2) positioning the HCW airway in the opposite direction to the main airflow would also reduce its exposure.
CONCLUSIONS CONCLUSIONS
This study document the presence of SARS-CoV-2 on caregivers in negative pressure ICU room of an infected patient with or without the use of SGCG. The simulation provides help in the design improvement of SGCG and the caregivers positioning in the room.

Identifiants

pubmed: 38040038
pii: S0195-6701(23)00380-8
doi: 10.1016/j.jhin.2023.11.007
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors have no conflicts of interest to disclose.

Auteurs

Cecilia Rotava Buratti (C)

Pediatric Intensive Care Unit, Department of Pediatrics, Hospital da Criança Santo Antônio, Porto Alegre, Rio Grande do Sul, Brazil; Graduate Program in Child and Adolescent Health, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Marc Veillette (M)

Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Québec-Université Laval, Québec, Québec, Canada.

Armelle Bridier (A)

Pediatric Intensive Care, Department of Pediatrics, Purpan Hospital, University of Toulouse, Toulouse, Occitanie, France.

Carl Eric Aubin (CE)

Polytechnique Montreal & Researcher, University Hospital Centre Sainte-Justine, Montréal, Québec, Canada.

Mélanie Lebrun (M)

Dassault Systèmes Simulia Corporation, Vélizy-Villacoublay, Yvelines, France.

Arul Kumaran Ammaiyappan (A)

Dassault Systèmes Simulia Corporation, Waltham, MA, USA.

Emmanuel Vanoli (E)

Dassault Systèmes Simulia Corporation, Vélizy-Villacoublay, Yvelines, France.

Cyril Crawford (C)

Dassault Systèmes Simulia Corporation, Vélizy-Villacoublay, Yvelines, France.

Caroline Duchaine (C)

Université Laval, Canada Research Chair on Bioaerosols, Québec, Québec, Canada.

Philippe Jouvet (P)

Pediatric Intensive Care Unit, Department of Pediatrics, University Hospital Centre Sainte-Justine, Montréal, Québec, Canada. Electronic address: philippe.jouvet.med@ssss.gouv.qc.ca.

Classifications MeSH