Recent Advances and Therapeutic Implications of 2-Oxoglutarate-Dependent Dioxygenases in Ischemic Stroke.
2-Oxoglutarate-dependent dioxygenases
Advances
Ischemic stroke
Therapeutic implications
Journal
Molecular neurobiology
ISSN: 1559-1182
Titre abrégé: Mol Neurobiol
Pays: United States
ID NLM: 8900963
Informations de publication
Date de publication:
02 Dec 2023
02 Dec 2023
Historique:
received:
04
08
2023
accepted:
08
11
2023
medline:
2
12
2023
pubmed:
2
12
2023
entrez:
2
12
2023
Statut:
aheadofprint
Résumé
Ischemic stroke is a common disease with a high disability rate and mortality, which brings heavy pressure on families and medical insurance. Nowadays, the golden treatments for ischemic stroke in the acute phase mainly include endovascular therapy and intravenous thrombolysis. Some drugs are used to alleviate brain injury in patients with ischemic stroke, such as edaravone and 3-n-butylphthalide. However, no effective neuroprotective drug for ischemic stroke has been acknowledged. 2-Oxoglutarate-dependent dioxygenases (2OGDDs) are conserved and common dioxygenases whose activities depend on O
Identifiants
pubmed: 38041714
doi: 10.1007/s12035-023-03790-1
pii: 10.1007/s12035-023-03790-1
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Natural Science Foundation of China
ID : 82130042
Organisme : National Natural Science Foundation of China
ID : 81830040
Organisme : National Major Science and Technology Projects of China
ID : 2022ZD0211701
Organisme : National Major Science and Technology Projects of China
ID : 2021ZD0200700
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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