Case report of atypical undernutrition of hypoproteinemia type.
cavernous transformation of the portal vein
hypoproteinemia
portal thrombosis
undernutrition
Journal
Open life sciences
ISSN: 2391-5412
Titre abrégé: Open Life Sci
Pays: Poland
ID NLM: 101669614
Informations de publication
Date de publication:
2023
2023
Historique:
received:
15
05
2023
revised:
18
09
2023
accepted:
10
10
2023
medline:
4
12
2023
pubmed:
4
12
2023
entrez:
4
12
2023
Statut:
epublish
Résumé
Albumin and prealbumin serve as vital markers reflecting hepatic synthesis activity and overall body nutrient status. Hypoproteinemia can result from various etiological factors, with reduced blood inflow into the liver due to portal vein thrombosis being one such cause. However, literature addressing this specific association remains limited. This report presents an atypical case of malnutrition involving a patient who experienced prolonged hypoproteinemia attributable to a gradual decline in hepatic blood perfusion caused by progressive portal thrombosis and cavernous transformation of the portal vein (CTPV). The case encompasses an in-depth analysis of the factors contributing to undernutrition, the etiology and diagnosis of hypoproteinemia, and its clinical implications. Vigilance for the presence of hypoproteinemia is essential in the management of patients afflicted by progressive portal vein thrombosis complicated by CTPV. Timely and effective interventions aimed at rectifying hypoproteinemia can significantly enhance clinical outcomes. Moreover, reduced hepatic blood flow should be considered a plausible underlying cause in cases of unexplained hypoproteinemia, warranting thorough evaluation. This case underscores the importance of recognizing the intricate interplay between hepatic vascular pathology and protein homeostasis in clinical practice.
Identifiants
pubmed: 38045486
doi: 10.1515/biol-2022-0766
pii: biol-2022-0766
pmc: PMC10693009
doi:
Types de publication
Case Reports
Langues
eng
Pagination
20220766Informations de copyright
© 2023 the author(s), published by De Gruyter.
Déclaration de conflit d'intérêts
Conflict of interest: Authors state no conflict of interest.
Références
JPEN J Parenter Enteral Nutr. 2019 Jan;43(1):32-40
pubmed: 30175461
Front Med (Lausanne). 2022 Mar 24;9:853138
pubmed: 35402447
Am J Physiol Gastrointest Liver Physiol. 2023 Nov 1;325(5):G391-G397
pubmed: 37605837
Ann Pharmacother. 2021 Jun;55(6):798-804
pubmed: 32909438
JPEN J Parenter Enteral Nutr. 2019 Feb;43(2):181-193
pubmed: 30288759
JHEP Rep. 2023 May 05;5(8):100785
pubmed: 37456673
Gastroenterologe. 2021;16(2):79-89
pubmed: 33613777
Curr Opin Gastroenterol. 2020 May;36(3):238-244
pubmed: 32073507
Zhonghua Gan Zang Bing Za Zhi. 2020 Nov 20;28(11):977-980
pubmed: 33256288
Clin Nutr. 2003 Jun;22(3):321-36
pubmed: 12765673
Gut. 2020 Jun;69(6):1127-1138
pubmed: 32102926
Br J Community Nurs. 2022 Jan 2;27(1):12-16
pubmed: 34990267
Turk J Med Sci. 2020 Feb 25;50(2):398-404
pubmed: 32093441
Hepatol Commun. 2023 Mar 30;7(4):
pubmed: 36996004
Ann Clin Biochem. 2022 Jan;59(1):7-14
pubmed: 32429677
Front Nutr. 2022 Jun 17;9:906511
pubmed: 35782947
Nutrition. 2022 Apr;96:111565
pubmed: 35066367
Ann Transl Med. 2020 Jul;8(14):889
pubmed: 32793733