Prevalence of Acetylsalicylic Acid Use for Primary Prevention of Cardiovascular Disease Amongst Older Adults From 2017-2021: a Retrospective Cross-Sectional Study.

aged aspirin cardiovascular disease primary prevention

Journal

Canadian geriatrics journal : CGJ
ISSN: 1925-8348
Titre abrégé: Can Geriatr J
Pays: Canada
ID NLM: 101579189

Informations de publication

Date de publication:
Dec 2023
Historique:
medline: 4 12 2023
pubmed: 4 12 2023
entrez: 4 12 2023
Statut: epublish

Résumé

Three landmark trials on the use of acetylsalicylic acid (ASA) for primary prevention of cardiovascular disease (CVD) were published in 2018. Since then, major clinical practice guidelines have been updated with recommendations against the routine use of ASA for primary CVD prevention, particularly in older adults. However, little is known about the uptake of this evidence into real world practice. The purpose of this study was to assess the change in ASA usage for primary prevention of CVD in older adults between 2017 and 2021. A retrospective cross-sectional study of ASA use for primary prevention in ambulatory older adults without known CVD in an urban Canadian city was conducted. Seven hundred and fifty-six participants were included. The mean age was 78.9 years (standard deviation 7.9) and 64.8% were female. One hundred and thirty (17.2%) participants used ASA for primary prevention, including 20.3% in 2017, 17.0% in 2018, 21.8% in 2019, 16.3% in 2020, and 11.0% in 2021 ( Use of ASA for primary CVD prevention in older Canadians decreased between 2017 and 2021, suggesting an uptake of clinical trial data and practice guideline recommendations. Focusing on deprescribing of ASA for primary CVD prevention continues to be warranted, given the risks associated with ASA in this population.

Sections du résumé

Background UNASSIGNED
Three landmark trials on the use of acetylsalicylic acid (ASA) for primary prevention of cardiovascular disease (CVD) were published in 2018. Since then, major clinical practice guidelines have been updated with recommendations against the routine use of ASA for primary CVD prevention, particularly in older adults. However, little is known about the uptake of this evidence into real world practice. The purpose of this study was to assess the change in ASA usage for primary prevention of CVD in older adults between 2017 and 2021.
Methods UNASSIGNED
A retrospective cross-sectional study of ASA use for primary prevention in ambulatory older adults without known CVD in an urban Canadian city was conducted.
Results UNASSIGNED
Seven hundred and fifty-six participants were included. The mean age was 78.9 years (standard deviation 7.9) and 64.8% were female. One hundred and thirty (17.2%) participants used ASA for primary prevention, including 20.3% in 2017, 17.0% in 2018, 21.8% in 2019, 16.3% in 2020, and 11.0% in 2021 (
Conclusions UNASSIGNED
Use of ASA for primary CVD prevention in older Canadians decreased between 2017 and 2021, suggesting an uptake of clinical trial data and practice guideline recommendations. Focusing on deprescribing of ASA for primary CVD prevention continues to be warranted, given the risks associated with ASA in this population.

Identifiants

pubmed: 38045883
doi: 10.5770/cgj.26.693
pii: cgj-26-517
pmc: PMC10684304
doi:

Types de publication

Journal Article

Langues

eng

Pagination

517-523

Informations de copyright

© 2023 Author(s).

Déclaration de conflit d'intérêts

CONFLICT OF INTEREST DISCLOSURES We have read and understood the Canadian Geriatrics Journal’s policy on disclosing conflicts of interest and declare that we have none.

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Auteurs

Jennifer Bolt (J)

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver.
Pharmacy Services, Interior Health Authority, Kelowna.

Arden R Barry (AR)

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver.
Lower Mainland Pharmacy Services, Fraser Health Authority, Surrey.

Colleen Inglis (C)

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver.
Pharmacy Services, Island Health Authority, Courtenay, BC.

Stephanie Lin (S)

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver.

Jeffrey Pan (J)

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver.

Classifications MeSH