Factors associated with secondary coronary artery disease in rheumatoid arthritis patients: A systematic review and meta-analysis based on observational studies.
coronary artery disease
prognosis
rheumatoid arthritis
risk factor
Journal
Musculoskeletal care
ISSN: 1557-0681
Titre abrégé: Musculoskeletal Care
Pays: England
ID NLM: 101181344
Informations de publication
Date de publication:
04 Dec 2023
04 Dec 2023
Historique:
revised:
16
11
2023
received:
11
10
2023
accepted:
17
11
2023
medline:
4
12
2023
pubmed:
4
12
2023
entrez:
4
12
2023
Statut:
aheadofprint
Résumé
The main objective of this systematic review was to investigate the factors influencing the development of coronary artery disease (CAD) in patients with rheumatoid arthritis (RA). PubMed, Embase, Web of Science, Wan Fang Date, CBM, CNKI, and VIP databases were systematically searched to select the relevant literature. The quality of the incorporated studies was assessed with reference to the Newcastle-Ottawa Scale. Stata16 was adopted to summarise the odds ratios, risk ratios, hazard ratios, and 95% confidence intervals for meta-analysis. A total of 29 studies were included in this analysis, wherein the average age of RA patients was 50.5-81 years and the proportion of women was 44.4%-92%. The present meta-analysis suggested that increased CAD risk in RA patients was associated with age, male gender, smoking, glucocorticoids, Health Assessment Questionnaire scores, hyperlipidaemia, hypertension, diabetes, and C-reactive protein concentration. The present systematic review revealed the influencing factors of secondary CAD in RA patients, some of which could reduce the risk of secondary CAD through effective interventions, such as smoking cessation, exercise, and medications. However, the effects of age, RA severity, and different medication subgroups on CAD risk stratification warrant further investigation.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Natural Science Foundation of China
ID : 81873184
Informations de copyright
© 2023 John Wiley & Sons Ltd.
Références
Achuthan, S., Ahluwalia, J., Shafiq, N., Bhalla, A., Pareek, A., Chandurkar, N., & Malhotra, S. (2015). Hydroxychloroquine's efficacy as an antiplatelet agent study in healthy volunteers: A proof of concept study. Journal of Cardiovascular Pharmacology and Therapeutics, 20(2), 174-180. https://doi.org/10.1177/1074248414546324
Agca, R., Heslinga, S. C., Rollefstad, S., Heslinga, M., McInnes, I. B., Peters, M. J., Kvien, T. K., Dougados, M., Radner, H., Atzeni, F., Primdahl, J., Sodergren, A., Wallberg Jonsson, S., van Rompay, J., Zabalan, C., Pedersen, T. R., Jacobsson, L., de Vlam, K., Gonzalez-Gay, M. A., … Nurmohamed, M. T. (2017). EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update. Annals of the Rheumatic Diseases, 76(1), 17-28. https://doi.org/10.1136/annrheumdis-2016-209775
Ahmed, S., Jacob, B., Carsons, S. E., De Leon, J., & Reiss, A. B. (2021). Treatment of cardiovascular disease in rheumatoid arthritis: A complex challenge with increased atherosclerotic risk. Pharmaceuticals, 15(1), 11. https://doi.org/10.3390/ph15010011
Ajeganova, S., Svensson, B., Hafstrom, I., & Grp, B. S. (2014). Low-dose prednisolone treatment of early rheumatoid arthritis and late cardiovascular outcome and survival: 10-year follow-up of a 2-year randomised trial. BMJ Open, 4(4), e004259. https://doi.org/10.1136/bmjopen-2013-004259
An, J. J., Nyarko, E., & Hamad, M. A. (2019). Prevalence of comorbidities and their associations with health-related quality of life and healthcare expenditures in patients with rheumatoid arthritis. Clinical Rheumatology, 38(10), 2717-2726. https://doi.org/10.1007/s10067-019-04613-2
Atzeni, F., Rodriguez-Carrio, J., Popa, C. D., Nurmohamed, M. T., Szucs, G., & Szekanecz, Z. (2021). Publisher Correction: Cardiovascular effects of approved drugs for rheumatoid arthritis. Nature Reviews Rheumatology, 17(5), 306. https://doi.org/10.1038/s41584-021-00616-z
Avina-Zubieta, J. A., Abrahamowicz, M., De Vera, M. A., Choi, H. K., Sayre, E. C., Rahman, M. M., Sylvestre, M. P., Wynant, W., Esdaile, J. M., & Lacaille, D. (2013). Immediate and past cumulative effects of oral glucocorticoids on the risk of acute myocardial infarction in rheumatoid arthritis: A population-based study. Rheumatology, 52(1), 68-75. https://doi.org/10.1093/rheumatology/kes353
Bili, A., Tang, X. Q., Pranesh, S., Bozaite, R., Morris, S. J., Antohe, J. L., Kirchner, H. L., & Wasko, M. C. M. (2014). Tumor necrosis factor alpha inhibitor use and decreased risk for incident coronary events in rheumatoid arthritis. Arthritis Care & Research, 66(3), 355-363. https://doi.org/10.1002/acr.22166
Bruce, B., & Fries, J. F. (2003). The Stanford health assessment questionnaire: A review of its history, issues, progress, and documentation. Journal of Rheumatology, 30(1), 167-178.
Chen, Y., Zeleniuch-Jacquotte, A., Arslan, A. A., Wojcik, O., Toniolo, P., Shore, R. E., Levitz, M., & Koenig, K. L. (2011). Endogenous hormones and coronary heart disease in postmenopausal women. Atherosclerosis, 216(2), 414-419. https://doi.org/10.1016/j.atherosclerosis.2011.01.053
Chen, Y. R., Hsieh, F. I., Chang, C. C., Chi, N. F., Wu, H. C., & Chiou, H. Y. (2018). Effect on risk of stroke and acute myocardial infarction of nonselective nonsteroidal anti-inflammatory drugs in patients with rheumatoid arthritis. The American Journal of Cardiology, 121(10), 1271-1277. https://doi.org/10.1016/j.amjcard.2018.01.044
Chung, C. P., Oeser, A., Raggi, P., Gebretsadik, T., Shintani, A. K., Sokka, T., Pincus, T., Avalos, I., & Stein, C. M. (2005). Increased coronary-artery atherosclerosis in rheumatoid arthritis - Relationship to disease duration and cardiovascular risk factors. Arthritis & Rheumatism, 52(10), 3045-3053. https://doi.org/10.1002/art.21288
del Rincon, I., Freeman, G. L., Haas, R. W., O'Leary, D. H., & Escalante, A. (2005). Relative contribution of cardiovascular risk factors and rheumatoid arthritis clinical manifestations to atherosclerosis. Arthritis & Rheumatism, 52(11), 3413-3423. https://doi.org/10.1002/art.21397
del Rincón, I. D., Williams, K., Stern, M. P., Freeman, G. L., & Escalante, A. (2001). High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis & Rheumatism, 44(12), 2737-2745. https://doi.org/10.1002/1529-0131(200112)44:12<2737::aid-art460>3.0.co;2-#
DerSimonian, R., & Laird, N. (1986). Meta-analysis in clinical trials. Controlled Clinical Trials, 7(3), 177-188. https://doi.org/10.1016/0197-2456(86)90046-2
Dessein, P. H., Joffe, B. I., Stanwix, A. E., Christian, B. F., & Veller, M. (2004). Glucocorticoids and insulin sensitivity in rheumatoid arthritis. Journal of Rheumatology, 31(5), 867-874.
De Vera, M. A., Choi, H., Abrahamowicz, M., Kopec, J., Goycochea-Robles, M. V., & Lacaille, D. (2011). Statin discontinuation and risk of acute myocardial infarction in patients with rheumatoid arthritis: A population-based cohort study. Annals of the Rheumatic Diseases, 70(6), 1020-1024. https://doi.org/10.1136/ard.2010.142455
Dixon, W. G., Watson, K. D., Lunt, M., Silman, A. J., Hyrich, K. L., & Symmons, D. P. M. (2007). Reduction in the incidence of myocardial infarction in patients with rheumatoid arthritis who respond to anti-tumor necrosis factor alpha therapy - Results from the British Society for Rheumatology Biologics Register. Arthritis & Rheumatism, 56(9), 2905-2912. https://doi.org/10.1002/art.22809
Duran, J., Peloquin, C., Zhang, Y. Q., & Felson, D. T. (2017). Primary prevention of myocardial infarction in rheumatoid arthritis using aspirin: A case-crossover study and a propensity score-matched cohort study. Journal of Rheumatology, 44(4), 418-424. https://doi.org/10.3899/jrheum.160930
Egger, M., Davey Smith, G., Schneider, M., & Minder, C. (1997). Bias in meta-analysis detected by a simple, graphical test. BMJ, 315(7109), 629-634. https://doi.org/10.1136/bmj.315.7109.629
Evans, M. R., Escalante, A., Battafarano, D. F., Freeman, G. L., O'Leary, D. H., & del Rincon, I. (2011). Carotid atherosclerosis predicts incident acute coronary syndromes in rheumatoid arthritis. Arthritis & Rheumatism, 63(5), 1211-1220. https://doi.org/10.1002/art.30265
Firestein, G. S. (2003). Evolving concepts of rheumatoid arthritis. Nature, 423(6937), 356-361. https://doi.org/10.1038/nature01661
Franceschi, C., Garagnani, P., Parini, P., Giuliani, C., & Santoro, A. (2018). Inflammaging: A new immune-metabolic viewpoint for age-related diseases. Nature Reviews Endocrinology, 14(10), 576-590. https://doi.org/10.1038/s41574-018-0059-4
Gasparyan, A. Y., Cocco, G., & Pandolfi, S. (2012). Cardiac complications in rheumatoid arthritis in the absence of occlusive coronary pathology. Rheumatology International, 32(2), 461-464. https://doi.org/10.1007/s00296-009-1318-4
Giles, J. T., Szklo, M., Post, W., Petri, M., Blumenthal, R. S., Lam, G., Gelber, A. C., Detrano, R., Scott, W. W., Jr., Kronmal, R. A., & Bathon, J. M. (2009). Coronary arterial calcification in rheumatoid arthritis: Comparison with the multi-ethnic study of atherosclerosis. Arthritis Research and Therapy, 11(2), R36. https://doi.org/10.1186/ar2641
Gluszek, J., Wierzowiecka, M., Niklas, K., & Niklas, A. (2020). The importance of homocysteine in the development of cardiovascular complications in patients with rheumatoid arthritis. Reumatologia, 58(5), 282-288. https://doi.org/10.5114/reum.2020.99732
Goff, D. C., Jr., Lloyd-Jones, D. M., Bennett, G., Coady, S., D'AgostinoSr, R. B., Gibbons, R., Greenland, P., Lackland, D. T., Levy, D., O'Donnell, C. J., Robinson, J. G., Schwartz, J. S., Shero, S. T., Smith, S. C., Jr., Sorlie, P., Stone, N. J., & Wilson, P. W. F. (2014). 2013 ACC/AHA guideline on the assessment of cardiovascular risk: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Journal of the American College of Cardiology, 63(25 Pt B), 2935-2959. https://doi.org/10.1016/j.jacc.2013.11.005
Goldston, K., & Baillie, A. J. (2008). Depression and coronary heart disease: A review of the epidemiological evidence, explanatory mechanisms and management approaches. Clinical Psychology Review, 28(2), 288-306. https://doi.org/10.1016/j.cpr.2007.05.005
Hare, D. L., Toukhsati, S. R., Johansson, P., & Jaarsma, T. (2014). Depression and cardiovascular disease: A clinical review. European Heart Journal, 35(21), 1365-1372. https://doi.org/10.1093/eurheartj/eht462
Hasan, T., Arora, R., Bansal, A. K., Bhattacharya, R., Sharma, G. S., & Singh, L. R. (2019). Disturbed homocysteine metabolism is associated with cancer. Experimental and Molecular Medicine, 51(2), 1-13. https://doi.org/10.1038/s12276-019-0216-4
Haskell, W. L., Lee, I. M., Pate, R. R., Powell, K. E., Blair, S. N., Franklin, B. A., Macera, C. A., Heath, G. W., Thompson, P. D., & Bauman, A. (2007). Physical activity and public health - Updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation, 116(9), 1081-1093. https://doi.org/10.1161/Circulationaha.107.185649
Hassan, S., Antonelli, M., & Ballou, S. (2015). Red cell distribution width: A measure of cardiovascular risk in rheumatoid arthritis patients? Clinical Rheumatology, 34(6), 1053-1057. https://doi.org/10.1007/s10067-015-2945-7
Hung, Y. M., Lin, L. C., Chen, C. M., Chiou, J. Y., Wang, Y. H., Wang, P. Y. P., & Wei, J. C. C. (2017). The effect of anti-rheumatic medications for coronary artery diseases risk in patients with rheumatoid arthritis might be changed over time: A nationwide population-based cohort study. PLoS One, 12(6), e0179081. https://doi.org/10.1371/journal.pone.0179081
Hung, Y. M., Wang, Y. H., Lin, L. C., Wang, P. Y. P., Chiou, J. Y., & Wei, J. C. C. (2018). Hydroxychloroquine may be associated with reduced risk of coronary artery diseases in patients with rheumatoid arthritis: A nationwide population-based cohort study. International Journal of Clinical Practice, 72(5), e13095. https://doi.org/10.1111/ijcp.13095
Im, C. H., Kim, N. R., Kang, J. W., Kim, J. H., Kang, J. Y., Bae, G. B., Nam, E. J., & Kang, Y. M. (2015). Inflammatory burden interacts with conventional cardiovascular risk factors for carotid plaque formation in rheumatoid arthritis. Rheumatology, 54(5), 808-815. https://doi.org/10.1093/rheumatology/keu376
Jie, L., Zi-ning, Y., Li, F., Dan, S., Jun, H., & Ling, C. (2020). Establishment of nomogram prediction model of coronary heart disease risk in patients with rheumatoid arthritis. Journal of Medical Postgraduates, 33(10), 1071-1075.
Kaplan, M. J. (2010). Cardiovascular complications of rheumatoid arthritis: Assessment, prevention, and treatment. Rheumatic Disease Clinics of North America, 36(2), 405-426. https://doi.org/10.1016/j.rdc.2010.02.002
Ljung, L., Simard, J. F., Jacobsson, L., Rantapaa-Dahlqvist, S., Askling, J., & Sweden, A.-R. T. (2012). Treatment with tumor necrosis factor inhibitors and the risk of acute coronary syndromes in early rheumatoid arthritis. Arthritis & Rheumatism, 64(1), 42-52. https://doi.org/10.1002/art.30654
Low, A. S. L., Symmons, D. P. M., Lunt, M., Mercer, L. K., Gale, C. P., Watson, K. D., Dixon, W. G., Hyrich, K. L., Rheumatology, B. S., & Consortium, B. C. C. (2017). Relationship between exposure to tumour necrosis factor inhibitor therapy and incidence and severity of myocardial infarction in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 76(4), 654-660. https://doi.org/10.1136/annrheumdis-2016-209784
Mantel, A., Holmqvist, M., Nyberg, F., Tornling, G., Frisell, T., Alfredsson, L., & Askling, J. (2015). Risk factors for the rapid increase in risk of acute coronary events in patients with new-onset rheumatoid arthritis: A nested case-control study. Arthritis & Rheumatology, 67(11), 2845-2854. https://doi.org/10.1002/art.39267
McDevitt, H., Munson, S., Ettinger, R., & Wu, A. (2002). Multiple roles for tumor necrosis factor-alpha and lymphotoxin alpha/beta in immunity and autoimmunity. Arthritis Research, 4(Suppl 3), S141-S152. https://doi.org/10.1186/ar570
Meissner, Y., Zink, A., Kekow, J., Rockwitz, K., Liebhaber, A., Zinke, S., Gerhold, K., Richter, A., Listing, J., & Strangfeld, A. (2016). Impact of disease activity and treatment of comorbidities on the risk of myocardial infarction in rheumatoid arthritis. Arthritis Research and Therapy, 18(1), 183. https://doi.org/10.1186/s13075-016-1077-z
Meune, C., Touze, E., Trinquart, L., & Allanore, Y. (2009). Trends in cardiovascular mortality in patients with rheumatoid arthritis over 50 years: A systematic review and meta-analysis of cohort studies. Rheumatology, 48(10), 1309-1313. https://doi.org/10.1093/rheumatology/kep252
Micha, R., Imamura, F., von Ballmoos, M. W., Solomon, D. H., Hernan, M. A., Ridker, P. M., & Mozaffarian, D. (2011). Systematic review and meta-analysis of methotrexate use and risk of cardiovascular disease. The American Journal of Cardiology, 108(9), 1362-1370. https://doi.org/10.1016/j.amjcard.2011.06.054
Mohammad, K. A., & Salomon, J. A. (2017). Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: A systematic analysis from the global burden of disease study 2015 (vol 389, pg 1885, 2015). Lancet, 390(10103), 1644.
Morris, S. J., Wasko, M. C. M., Antohe, J. L., Sartorius, J. A., Kirchner, H. L., Dancea, S., & Bili, A. (2011). Hydroxychloroquine use associated with improvement in lipid profiles in rheumatoid arthritis patients. Arthritis Care & Research, 63(4), 530-534. https://doi.org/10.1002/acr.20393
Myasoedova, E., Crowson, C. S., Kremers, H. M., Roger, V. L., Fitz-Gibbon, P. D., Therneau, T. M., & Gabriel, S. E. (2011). Lipid paradox in rheumatoid arthritis: The impact of serum lipid measures and systemic inflammation on the risk of cardiovascular disease. Annals of the Rheumatic Diseases, 70(3), 482-487. https://doi.org/10.1136/ard.2010.135871
Navarro-Millan, I., Yang, S., DuVall, S. L., Chen, L., Baddley, J., Cannon, G. W., Delzell, E. S., Zhang, J., Safford, M. M., Patkar, N. M., Mikuls, T. R., Singh, J. A., & Curtis, J. R. (2016). Association of hyperlipidaemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: Data from the National Veterans Health Administration. Annals of the Rheumatic Diseases, 75(2), 341-347. https://doi.org/10.1136/annrheumdis-2013-204987
Nilsson, P. M., Khalili, P., & Franklin, S. S. (2014). Blood pressure and pulse wave velocity as metrics for evaluating pathologic ageing of the cardiovascular system. Blood Pressure, 23(1), 17-30. https://doi.org/10.3109/08037051.2013.796142
Nossent, H. (2000). Risk of cardiovascular events and effect on mortality in patients with rheumatoid arthritis. Journal of Rheumatology, 27(9), 2282-2283.
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., … Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, n71. https://doi.org/10.1136/bmj.n71
Panoulas, V. F., Metsios, G. S., Pace, A. V., John, H., Treharne, G. J., Banks, M. J., & Kitas, G. D. (2008). Hypertension in rheumatoid arthritis. Rheumatology, 47(9), 1286-1298. https://doi.org/10.1093/rheumatology/ken159
Park, Y., Booth, F. W., Lee, S., Laye, M. J., & Zhang, C. H. (2012). Physical activity opposes coronary vascular dysfunction induced during high fat feeding in mice. Journal of Physiology-London, 590(17), 4255-4268. https://doi.org/10.1113/jphysiol.2012.234856
Pope, J. (2011). Measures of systemic sclerosis (scleroderma): Health Assessment Questionnaire (HAQ) and Scleroderma HAQ (SHAQ), physician- and patient-rated global assessments, Symptom Burden Index (SBI), University of California, Los Angeles, Scleroderma Clinical Trials Consortium Gastrointestinal Scale (UCLA SCTC GIT) 2.0, Baseline Dyspnea Index (BDI) and Transition Dyspnea Index (TDI) (Mahler's Index), Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR), and Raynaud's Condition Score (RCS). Arthritis Care & Research, 63(Suppl 11), S98-S111. https://doi.org/10.1002/acr.20598
Pushpakumar, S., Kundu, S., & Sen, U. (2014). Endothelial dysfunction: The link between homocysteine and hydrogen sulfide. Current Medicinal Chemistry, 21(32), 3662-3672. https://doi.org/10.2174/0929867321666140706142335
Radovits, B. J., Popa-Diaconu, D. A., Popa, C., Eijsbouts, A., Laan, R. F. J. M., van Riel, P. L. C. M., & Fransen, J. (2009). Disease activity as a risk factor for myocardial infarction in rheumatoid arthritis. Annals of the Rheumatic Diseases, 68(8), 1271-1276. https://doi.org/10.1136/ard.2008.089862
Ridker, P. M. (2009). Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT). Journal of Thrombosis and Haemostasis, 7(Suppl 1), 332-339. https://doi.org/10.1111/j.1538-7836.2009.03404.x
Roubille, C., Richer, V., Starnino, T., McCourt, C., McFarlane, A., Fleming, P., Siu, S., Kraft, J., Lynde, C., Pope, J., Gulliver, W., Keeling, S., Dutz, J., Bessette, L., Bissonnette, R., & Haraoui, B. (2015). The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis. Annals of the Rheumatic Diseases, 74(3), 480-489. https://doi.org/10.1136/annrheumdis-2014-206624
Sandoo, A., Chanchlani, N., Hodson, J., Smith, J. P., Douglas, K. M., & Kitas, G. D. (2013). Classical cardiovascular disease risk factors associate with vascular function and morphology in rheumatoid arthritis: A six-year prospective study. Arthritis Research and Therapy, 15(6), R203. https://doi.org/10.1186/ar4396
Scherrer, J. F., Virgo, K. S., Zeringue, A., Bucholz, K. K., Jacob, T., Johnson, R. G., True, W. R., Carney, R. M., Freedland, K. E., Xian, H., Caplan, L., McDonald, J., & Eisen, S. A. (2009). Depression increases risk of incident myocardial infarction among Veterans Administration patients with rheumatoid arthritis. General Hospital Psychiatry, 31(4), 353-359. https://doi.org/10.1016/j.genhosppsych.2009.04.001
Smolen, J. S., Landewe, R. B. M., Bijlsma, J. W. J., Burmester, G. R., Dougados, M., Kerschbaumer, A., McInnes, I. B., Sepriano, A., van Vollenhoven, R. F., de Wit, M., Aletaha, D., Aringer, M., Askling, J., Balsa, A., Boers, M., den Broeder, A. A., Buch, M. H., Buttgereit, F., Caporali, R., … vander Heijde, D. (2020). EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update. Annals of the Rheumatic Diseases, 79(6), 685-699. https://doi.org/10.1136/annrheumdis-2019-216655
Solomon, D. H., Avorn, J., Katz, J. N., Weinblatt, M. E., Setoguchi, S., Levin, R., & Schneeweiss, S. (2006). Immunosuppressive medications and hospitalization for cardiovascular events in patients with rheumatoid arthritis. Arthritis & Rheumatism, 54(12), 3790-3798. https://doi.org/10.1002/art.22255
Solomon, D. H., Curtis, J. R., Saag, K. G., Lii, J., Chen, L., Harrold, L. R., Herrinton, L. J., Graham, D. J., Kowal, M. K., Kuriya, B., Liu, L., Griffin, M. R., Lewis, J. D., & Rassen, J. A. (2013). Cardiovascular risk in rheumatoid arthritis: Comparing TNF-alpha blockade with nonbiologic DMARDs. The American Journal of Medicine, 126(8), 730.e9-e17. https://doi.org/10.1016/j.amjmed.2013.02.016
Stuhlinger, M. C., Tsao, P. S., Her, J. H., Kimoto, M., Balint, R. F., & Cooke, J. P. (2001). Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation, 104(21), 2569-2575. https://doi.org/10.1161/hc4601.098514
Suarez-Almazor, M. E., Belseck, E., Shea, B., Homik, J., Wells, G., & Tugwell, P. (2000). Antimalarials for treating rheumatoid arthritis. Cochrane Database of Systematic Reviews, 4(7), CD000959. https://doi.org/10.1002/14651858.CD000959
Suissa, S., Bernatsky, S., & Hudson, M. (2006). Antirheumatic drug use and the risk of acute myocardial infarction. Arthritis & Rheumatism-Arthritis Care & Research, 55(4), 531-536. https://doi.org/10.1002/art.22094
Trelle, S., Reichenbach, S., Wandel, S., Hildebrand, P., Tschannen, B., Villiger, P. M., Egger, M., & Juni, P. (2011). Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ, 342(jan11 1), c7086. https://doi.org/10.1136/bmj.c7086
van Halm, V. P., Peters, M. J. L., Voskuyl, A. E., Boers, M., Lems, W. F., Visser, M., Stehouwer, C. D. A., Spijkerman, A. M. W., Dekker, J. M., Nijpels, G., Heine, R. J., Bouter, L. M., Smulders, Y. M., Dijkmans, B. A. C., & Nurmohamed, M. T. (2009). Rheumatoid arthritis versus diabetes as a risk factor for cardiovascular disease: a cross-sectional study, the CARRE Investigation. Annals of the Rheumatic Diseases, 68(9), 1395-1400. https://doi.org/10.1136/ard.2008.094151
van Leuven, S. I., Franssen, R., Kastelein, J. J., Levi, M., Stroes, E. S. G., & Tak, P. P. (2008). Systemic inflammation as a risk factor for atherothrombosis. Rheumatology, 47(1), 3-7. https://doi.org/10.1093/rheumatology/kem202
Wallace, D. J. (1996). The history of antimalarials. Lupus, 5(Suppl 1), S2-S3. https://doi.org/10.1177/0961203396005001021
Wei, T. T., Yang, B. W., Liu, H. N., Xin, F. R., & Fu, L. Y. (2020). Development and validation of a nomogram to predict coronary heart disease in patients with rheumatoid arthritis in northern China. Aging-Us, 12(4), 3190-3204. https://doi.org/10.18632/aging.102823
Weiping, C., Lili, P., Jin, W., Hua, L., & Tian, W. (2016). Relative factors of coronary artery disease in middle-aged and elderly patients with rheumatoid arthritis. China Medicine, 11(5), 629-633.
Weiping, C., Lili, P., Jin, W., & Xue, T. (2014). Clinical analysis of rheumatoid arthritis with coronary artery disease. Journal of Cardiovascular and Pulmonary Diseases, 33(03), 320-322.
Weiwei, C. (2017). Is it feasible to implement “three-high condominium” in basic hospitals? Chinese Journal of Hypertension, 25(10), 908-912. https://doi.org/10.16439/j.cnki.1673-7245.2017.10.005
Wells, G., Shea, B., O'Connell, D., Peterson, J., Welch, V., Losos, M., & Tugwell, P. (2022). The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Retrieved February 10, from http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp
Whooley, M. A., de Jonge, P., Vittinghoff, E., Otte, C., Moos, R., Carney, R. M., Ali, S., Dowray, S., Na, B., Feldman, M. D., Schiller, N. B., & Browner, W. S. (2008). Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA, 300(20), 2379-2388. https://doi.org/10.1001/jama.2008.711
Wolfe, F. (2000). The effect of smoking on clinical, laboratory, and radiographic status in rheumatoid arthritis. Journal of Rheumatology, 27(3), 630-637.
Wolfe, F., & Michaud, K. (2008). The risk of myocardial infarction and pharmacologic and nonpharmacologic myocardial infarction predictors in rheumatoid arthritis - A cohort and nested case-control analysis. Arthritis & Rheumatism, 58(9), 2612-2621. https://doi.org/10.1002/art.23811
Wu, M. Y., Huang, M. C., Liao, H. H., Chiang, J. H., Lee, Y. C., Hsu, C. Y., Sun, M. F., & Yen, H. R. (2018). Acupuncture decreased the risk of coronary heart disease in patients with rheumatoid arthritis in Taiwan: A nationwide propensity score-matched study. BMC Complementary and Alternative Medicine, 18(1), 341. https://doi.org/10.1186/s12906-018-2384-5
Xing, L., Yu-feng, Y., Bin, M., Lin, N., & Jian-hua, X. (2016). Clinical study of 157 rheumatoid arthritis patients' combination and complication. Chinese Journal of Disease Control & Prevention, 20(02), 201-203. https://doi.org/10.16462/j.cnki.zhjbkz.2016.02.024
Yuan, S., Jing, X., Ping, W., & Jinghua, L. (2020). Retrospective analysis of clinical data of rheumatoid arthritis combined with coronary heart disease. Chinese General Practice, 23(S1), 58-60.
Yxfeldt, A., Wallberg-Jonsson, S., Hultdin, J., & Rantapaa-Dahlqvist, S. (2003). Homocysteine in patients with rheumatoid arthritis in relation to inflammation and B-vitamin treatment. Scandinavian Journal of Rheumatology, 32(4), 205-210. https://doi.org/10.1080/03009740310003686
Zhang, J., Chen, L., Delzell, E., Muntner, P., Hillegass, W. B., Safford, M. M., Millan, I. Y. N., Crowson, C. S., & Curtis, J. R. (2014). The association between inflammatory markers, serum lipids and the risk of cardiovascular events in patients with rheumatoid arthritis. Postgraduate Medical Journal, 90(1070), 1301-1308. https://doi.org/10.1136/annrheumdis-2013-204715
Zhang, J., & Yu, K. F. (1998). What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA, 280(19), 1690-1691. https://doi.org/10.1001/jama.280.19.1690