Gonadal hormones in borderline personality disorder: implications for understanding symptoms and supporting treatment.
Borderline personality disorder
Mood
Oestrogens
Serotonin
Women
Journal
Archives of women's mental health
ISSN: 1435-1102
Titre abrégé: Arch Womens Ment Health
Pays: Austria
ID NLM: 9815663
Informations de publication
Date de publication:
05 Dec 2023
05 Dec 2023
Historique:
received:
02
10
2023
accepted:
23
11
2023
medline:
5
12
2023
pubmed:
5
12
2023
entrez:
5
12
2023
Statut:
aheadofprint
Résumé
To review the literature on the impact of gonadal hormones on features of borderline personality disorder. Oestrogen flux and absolute sex hormone levels are known to be associated with various mood states in women. We investigated whether this was particularly relevant for borderline symptoms in women with or without borderline personality disorder (BPD). Systematic literature review. There is some evidence that borderline symptoms are more severe during certain phases on the menstrual cycle in non-clinical samples of women. There is also a small evidence base that suggests that women with BPD show symptom exacerbation during the late luteal phase of their menstrual cycle. More work is required to establish the nature and mechanisms of interactions between gonadal hormones and symptom expression in BPD patients, and therapeutic endeavours need stringent empirical testing.
Sections du résumé
OBJECTIVE
OBJECTIVE
To review the literature on the impact of gonadal hormones on features of borderline personality disorder.
BACKGROUND
BACKGROUND
Oestrogen flux and absolute sex hormone levels are known to be associated with various mood states in women. We investigated whether this was particularly relevant for borderline symptoms in women with or without borderline personality disorder (BPD).
METHODS
METHODS
Systematic literature review.
DISCUSSION
CONCLUSIONS
There is some evidence that borderline symptoms are more severe during certain phases on the menstrual cycle in non-clinical samples of women. There is also a small evidence base that suggests that women with BPD show symptom exacerbation during the late luteal phase of their menstrual cycle.
CONCLUSION
CONCLUSIONS
More work is required to establish the nature and mechanisms of interactions between gonadal hormones and symptom expression in BPD patients, and therapeutic endeavours need stringent empirical testing.
Identifiants
pubmed: 38051369
doi: 10.1007/s00737-023-01406-0
pii: 10.1007/s00737-023-01406-0
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.
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