A Bayesian multivariate factor analysis model for causal inference using time-series observational data on mixed outcomes.

Causal inference Contact tracing Data augmentation Factor analysis Policy evaluation

Journal

Biostatistics (Oxford, England)
ISSN: 1468-4357
Titre abrégé: Biostatistics
Pays: England
ID NLM: 100897327

Informations de publication

Date de publication:
06 Dec 2023
Historique:
received: 08 09 2022
revised: 15 10 2023
accepted: 16 10 2023
medline: 7 12 2023
pubmed: 7 12 2023
entrez: 7 12 2023
Statut: aheadofprint

Résumé

Assessing the impact of an intervention by using time-series observational data on multiple units and outcomes is a frequent problem in many fields of scientific research. Here, we propose a novel Bayesian multivariate factor analysis model for estimating intervention effects in such settings and develop an efficient Markov chain Monte Carlo algorithm to sample from the high-dimensional and nontractable posterior of interest. The proposed method is one of the few that can simultaneously deal with outcomes of mixed type (continuous, binomial, count), increase efficiency in the estimates of the causal effects by jointly modeling multiple outcomes affected by the intervention, and easily provide uncertainty quantification for all causal estimands of interest. Using the proposed approach, we evaluate the impact that Local Tracing Partnerships had on the effectiveness of England's Test and Trace programme for COVID-19.

Identifiants

pubmed: 38058013
pii: 7459857
doi: 10.1093/biostatistics/kxad030
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press.

Auteurs

Pantelis Samartsidis (P)

MRC Biostatistics Unit, East Forvie Building, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK.

Shaun R Seaman (SR)

MRC Biostatistics Unit, East Forvie Building, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK.

Abbie Harrison (A)

UK Health Security Agency, London, E14 4PU, UK.

Angelos Alexopoulos (A)

MRC Biostatistics Unit, East Forvie Building, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK.
Department of Economics, Athens University of Economics and Business, Athens, 104 34, Greece.

Gareth J Hughes (GJ)

UK Health Security Agency, London, E14 4PU, UK.

Christopher Rawlinson (C)

UK Health Security Agency, London, E14 4PU, UK.

Charlotte Anderson (C)

UK Health Security Agency, London, E14 4PU, UK.

André Charlett (A)

UK Health Security Agency, London, E14 4PU, UK.

Isabel Oliver (I)

UK Health Security Agency, London, E14 4PU, UK.

Daniela De Angelis (D)

MRC Biostatistics Unit, East Forvie Building, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK.
UK Health Security Agency, London, E14 4PU, UK.

Classifications MeSH