Bilateral intra-lymph node Warthin's tumor as a potential diagnostic pitfall mimicking metastatic carcinoma.
Warthin tumor
fine-needle aspiration
lymphatic metastasis
salivary gland neoplasms
Journal
Diagnostic cytopathology
ISSN: 1097-0339
Titre abrégé: Diagn Cytopathol
Pays: United States
ID NLM: 8506895
Informations de publication
Date de publication:
07 Dec 2023
07 Dec 2023
Historique:
received:
12
11
2023
accepted:
21
11
2023
medline:
7
12
2023
pubmed:
7
12
2023
entrez:
7
12
2023
Statut:
aheadofprint
Résumé
Warthin's tumor (WT) is a benign and frequent salivary gland tumor primarily affecting the parotid gland. In some cases, this tumor can involve the extra parotid region and affect cervical lymph nodes. Fine-needle aspiration can be the first step in the diagnostic approach to lymphadenopathy; however, specimens from intra-nodal WT can present a potential pitfall, leading to a misdiagnosis of metastasis. Here, we report an unusual case of a patient with bilateral WT in parotid lymph nodes misdiagnosed as metastases. In addition, we highlight the cytopathological aspects of WT to alert cytopathologists about this challenging diagnosis.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Informations de copyright
© 2023 Wiley Periodicals LLC.
Références
Bradley PJ, McGurk M. Incidence of salivary gland neoplasms in a defined UK population. Br J Oral Maxillofac Surg [Internet]. 2013;51(5):399-403. doi:10.1016/j.bjoms.2012.10.002
Patterson JW, Wright ED, Camden S. Extraparotid Warthin's tumor. J Am Acad Dermatol. 1999;40:468-470.
WHO. In: El-Naggar A, Chan J, Grandis J, Takata T, Slootweg P, eds. WHO Classification of Head and Neck Tumours. 4th ed. IARC: WHO press; 2017.
Sarkar A, Sharma N, Sharma S. Fine needle aspiration cytology utility in salivary gland tumor diagnosis. Indian J Otolaryngol Head Neck Surg. 2017;69(2):147-154.
Olsen SM, Moore EJ, Koch CA, Kasperbauer JL, Olsen KD. Oral cavity and oropharynx squamous cell carcinoma with metastasis to the parotid lymph nodes. Oral Oncol [Internet]. 2011;47(2):142-144. doi:10.1016/j.oraloncology.2010.11.010
Cope W, Naugler C, Taylor SM, Trites J, Hart RD, Bullock MJ. The Association of Warthin Tumor with salivary ductal inclusions in intra and periparotid lymph nodes. Head Neck Pathol. 2014;8(1):73-76.
Schwarz E, Hürlimann S, Soyka JD, Bortoluzzi L, Strobel K. FDG-positive Warthin's tumors in cervical lymph nodes mimicking metastases in tongue cancer staging with PET/CT. Otolaryngol Head Neck Surg [Internet]. 2009;140(1):134-135. doi:10.1016/j.otohns.2008.09.019
Al-Abbadi MA, Barroca H, Bode-Lesniewska B, et al. A proposal for the performance, classification, and reporting of lymph node fine-needle aspiration cytopathology: the Sydney system. Acta Cytol. 2020;64(4):306-322.
Gupta P, Gupta N, Kumar P, et al. Assessment of risk of malignancy by application of the proposed Sydney system for classification and reporting lymph node cytopathology. Cancer Cytopathol. 2021;129(9):701-718.
Pusztaszeri MP, Faquin WC. Cytologic evaluation of cervical lymph node metastases from cancers of unknown primary origin. Semin Diagn Pathol [Internet]. 2015;32(1):32-41. doi:10.1053/j.semdp.2014.12.002