COVID-19 breakthrough infections in type 1 diabetes mellitus: a cross-sectional study by the COVID-19 Vaccination in Autoimmune Diseases (COVAD) Group.


Journal

Rheumatology international
ISSN: 1437-160X
Titre abrégé: Rheumatol Int
Pays: Germany
ID NLM: 8206885

Informations de publication

Date de publication:
Jan 2024
Historique:
received: 07 09 2023
accepted: 14 10 2023
medline: 8 1 2024
pubmed: 7 12 2023
entrez: 7 12 2023
Statut: ppublish

Résumé

To investigate the frequency, profile, and severity of COVID-19 breakthrough infections (BI) in patients with type I diabetes mellitus (T1DM) compared to healthy controls (HC) after vaccination. The second COVID-19 Vaccination in Autoimmune Diseases (COVAD-2) survey is a multinational cross-sectional electronic survey which has collected data on patients suffering from various autoimmune diseases including T1DM. We performed a subgroup analysis on this cohort to investigate COVID-19 BI characteristics in patients with T1DM. Logistic regression with propensity score matching analysis was performed. A total of 9595 individuals were included in the analysis, with 100 patients having T1DM. Among the fully vaccinated cohort, 16 (16%) T1DM patients had one BI and 2 (2%) had two BIs. No morbidities or deaths were reported, except for one patient who required hospitalization with oxygen without admission to intensive care. The frequency, clinical features, and severity of BIs were not significantly different between T1DM patients and HCs after adjustment for confounding factors. Our study did not show any statistically significant differences in the frequency, symptoms, duration, or critical care requirements between T1DM and HCs after COVID-19 vaccination. Further research is needed to identify factors associated with inadequate vaccine response in patients with BIs, especially in patients with autoimmune diseases.

Identifiants

pubmed: 38060005
doi: 10.1007/s00296-023-05496-y
pii: 10.1007/s00296-023-05496-y
pmc: PMC10766674
doi:

Substances chimiques

COVID-19 Vaccines 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

73-80

Subventions

Organisme : Versus Arthritis
ID : 21992
Pays : United Kingdom

Investigateurs

Parikshit Sen (P)
Jessica Day (J)
Elena Nikiphorou (E)
Nelly Ziade (N)
Marcin Milchert (M)
Lorenzo Cavagna (L)
Yi Ming Chen (YM)
Ashima Makol (A)
Vishwesh Agarwal (V)
Aarat Patel (A)
John D Pauling (JD)
Chris Wincup (C)
Erick Adrian Zamora Tehozol (EAZ)
Jorge Rojas Serrano (JR)
Ignacia García-De La Torre (IG)
Iris J Colunga-Pedraza (IJ)
Javier Merayo-Chalico (J)
Okwara Celestine Chibuzo (OC)
Wanruchada Katchamart (W)
Phonpen Akawatcharangura Goo (PA)
Russka Shumnalieva (R)
Leonardo Santos Hoff (LS)
Lina El Kibbi (L)
Hussein Halabi (H)
Binit Vaidya (B)
Syahrul Sazliyana Shaharir (SS)
ATMTanveer Hasan (A)
Dzifa Dey (D)
Carlos Enrique Toro Gutiérrez (CET)
James B Lilleker (JB)
Babur Salim (B)
Tamer Gheita (T)
Oliver Distler (O)
Miguel A Saavedra (MA)
Sinan Kardes (S)
Laura Andreoli (L)
Daniele Lini (D)
Karen Schreiber (K)
Melinda Nagy Vince (MN)
Yogesh Preet Singh (YP)
Rajiv Ranjan (R)
Avinash Jain (A)
Sapan C Pandya (SC)
Rakesh Kumar Pilania (RK)
Aman Sharma (A)
Manesh Manoj M (MM)
Vikas Gupta (V)
Chengappa G Kavadichanda (CG)
Pradeepta Sekhar Patro (PS)
Sajal Ajmani (S)
Sanat Phatak (S)
Rudra Prosad Goswami (RP)
Abhra Chandra Chowdhury (AC)
Ashish Jacob Mathew (AJ)
Padnamabha Shenoy (P)
Ajay Asranna (A)
Keerthi Talari Bommakanti (KT)
Anuj Shukla (A)
Arunkumar R Pande (AR)
Kunal Chandwar (K)
Akanksha Ghodke (A)
Zoha Zahid Fazal (ZZ)
Döndü Üsküdar Cansu (DÜ)
Reşit Yıldırım (R)
Armen Yuri Gasparyan (AY)
Nicoletta Del Papa (N)
Gianluca Sambataro (G)
Atzeni Fabiola (A)
Marcello Govoni (M)
Simone Parisi (S)
Elena Bartoloni Bocci (EB)
Gian Domenico Sebastiani (GD)
Enrico Fusaro (E)
Marco Sebastiani (M)
Luca Quartuccio (L)
Franco Franceschini (F)
Pier Paolo Sainaghi (PP)
Giovanni Orsolini (G)
Rossella De Angelis (R)
Maria Giovanna Danielli (MG)
Vincenzo Venerito (V)
Silvia Grignaschi (S)
Alessandro Giollo (A)
Alessia Alluno (A)
Florenzo Ioannone (F)
Marco Fornaro (M)
Lisa S Traboco (LS)
Suryo Anggoro Kusumo Wibowo (SAK)
Jesús Loarce-Martos (J)
Sergio Prieto-González (S)
Raquel Aranega Gonzalez (RA)
Akira Yoshida (A)
Ran Nakashima (R)
Shinji Sato (S)
Naoki Kimura (N)
Yuko Kaneko (Y)
Takahisa Gono (T)
Stylianos Tomaras (S)
Fabian Nikolai Proft (FN)
Marie-Therese Holzer (MT)
Margarita Aleksandrovna Gromova (MA)
Or Aharonov (O)
Zoltán Griger (Z)
Ihsane Hmamouchi (I)
Imane El Bouchti (I)
Zineb Baba (Z)
Margherita Giannini (M)
François Maurier (F)
Julien Campagne (J)
Alain Meyer (A)
Daman Langguth (D)
Vidya Limaye (V)
Merrilee Needham (M)
Nilesh Srivastav (N)
Marie Hudson (M)
Océane Landon-Cardinal (O)
Wilmer Gerardo Rojas Zuleta (WGR)
Álvaro Arbeláez (Á)
Javier Cajas (J)
José António Pereira Silva (JAP)
João Eurico Fonseca (JE)
Olena Zimba (O)
Doskaliuk Bohdana (D)
Uyi Ima-Edomwonyi (U)
Ibukunoluwa Dedeke (I)
Emorinken Airenakho (E)
Nwankwo Henry Madu (NH)
Abubakar Yerima (A)
Hakeem Olaosebikan (H)
Becky A (B)
Oruma Devi Koussougbo (OD)
Elisa Palalane (E)
Ho So (H)
Manuel Francisco Ugarte-Gil (MF)
Lyn Chinchay (L)
José Proaño Bernaola (JP)
Victorio Pimentel (V)
Hanan Mohammed Fathi (HM)
Reem Hamdy A Mohammed (RHA)
Ghita Harifi (G)
Yurilís Fuentes-Silva (Y)
Karoll Cabriza (K)
Jonathan Losanto (J)
Nelly Colaman (N)
Antonio Cachafeiro-Vilar (A)
Generoso Guerra Bautista (GG)
Enrique Julio Giraldo Ho (EJG)
Raúl González (R)
Lilith Stange Nunez (LS)
Cristian Vergara M (CV)
Jossiell Then Báez (JT)
Hugo Alonzo (H)
Carlos Benito Santiago Pastelin (CBS)
Rodrigo García Salinas (RG)
Alejandro Quiñónez Obiols (AQ)
Nilmo Chávez (N)
Andrea Bran Ordóñez (AB)
Alberto Reyes Llerena (AR)
Radames Sierra-Zorita (R)
Dina Arrieta (D)
Eduardo Romero Hidalgo (ER)
Ricardo Saenz (R)
Idania Escalante M (I)
Wendy Calapaqui (W)
Ivonne Quezada (I)
Gabriela Arredondo (G)

Informations de copyright

© 2023. The Author(s).

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Auteurs

Suhrud Panchawagh (S)

Smt Kashibai Navale Medical College, Pune, India.

Naveen Ravichandran (N)

Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Bhupen Barman (B)

Department of Medicine, All India Institute of Medical Science (AIIMS), Guwahati, India.

Arvind Nune (A)

Department of Rheumatology, Southport and Ormskirk Hospital NHS Trust, Southport, PR8 6PN, UK.

Mahnoor Javaid (M)

Medical College, The Aga Khan University, Karachi, Pakistan.

Abraham Edgar Gracia-Ramos (AE)

Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, C.P. 02990, Del. AzcapotzalcoMexico City, Mexico.

Jessica Day (J)

Department of Rheumatology, Royal Melbourne Hospital, Parkville, VIC, 3050, Australia.
Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
Department of Medical Biology, University of Melbourne, Parkville, VIC, 3052, Australia.

Mrudula Joshi (M)

Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India.

Masataka Kuwana (M)

Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.

Sreoshy Saha (S)

Mymensingh Medical College, Mymensingh, Bangladesh.

Arunkumar R Pande (AR)

LEDTC Clinic, Uttar Pradesh, Gomti Nagar, Lucknow, India.

Carlo Vinicio Caballero-Uribe (CV)

Department of Medicine, Hospital Universidad del Norte, Barranquilla, Atlantico, Colombia.

Tsvetelina Velikova (T)

Medical Faculty, Sofia University St. Kliment Ohridski, 1 Kozyak Str., 1407, Sofia, Bulgaria.

Ioannis Parodis (I)

Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Johannes Knitza (J)

Medizinische Klinik 3-Rheumatologie und Immunologie, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054, Erlangen, Deutschland.

Esha Kadam (E)

Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, Maharashtra, India.

Ai Lyn Tan (AL)

NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK.
Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

Samuel Katsuyuki Shinjo (SK)

Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil.

Hiya Boro (H)

Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.

Rohit Aggarwal (R)

Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Vikas Agarwal (V)

Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Tulika Chatterjee (T)

Center for Outcomes Research, Department of Internal Medicine, University of Illinois College of Medicine Peoria, Peoria, IL, USA.

Latika Gupta (L)

Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, WV10 0QP, UK. drlatikagupta@gmail.com.
Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK. drlatikagupta@gmail.com.
Department of Rheumatology, City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK. drlatikagupta@gmail.com.

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