Integrin α

SARS-CoV-2 cell fusion inflammation integrin

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
12 Dec 2023
Historique:
medline: 7 12 2023
pubmed: 7 12 2023
entrez: 7 12 2023
Statut: ppublish

Résumé

The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infects host cells by engaging its spike (S) protein with human ACE2 receptor. Recent studies suggest the involvement of integrins in SARS-CoV-2 infection through interaction with the S protein, but the underlying mechanism is not well understood. This study investigated the role of integrin α

Identifiants

pubmed: 38060559
doi: 10.1073/pnas.2311913120
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2311913120

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL131836
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM137143
Pays : United States

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Heng Zhang (H)

Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, WI 53226.

Zhengli Wang (Z)

Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, WI 53226.

Huong T T Nguyen (HTT)

Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, WI 53226.

Abigail J Watson (AJ)

Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, WI 53226.

Qifang Lao (Q)

Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, WI 53226.

An Li (A)

Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, WI 53226.

Jieqing Zhu (J)

Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, WI 53226.
Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226.

Classifications MeSH