ANCA-negative ANCA-associated vasculitis: pitfalls of the 'vasculitis screen'.
ANCA
ANCA-associated vasculitis
eosinophilic granulomatous polyangiitis
vasculitis
Journal
Clinical medicine (London, England)
ISSN: 1473-4893
Titre abrégé: Clin Med (Lond)
Pays: England
ID NLM: 101092853
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
medline:
9
12
2023
pubmed:
9
12
2023
entrez:
8
12
2023
Statut:
ppublish
Résumé
Despite its recognition as an 'ANCA-associated vasculitis' (AAV), eosinophilic granulomatosis with polyangiitis (EGPA) is ANCA negative in up to 60% of cases. Herein, we report the case of a young man with a clinical syndrome highly suggestive of EGPA but with repeated negative ANCA serology, ultimately presenting with cardiac arrest before recognition of the primary systemic vasculitis, whereupon he received successful induction therapy with high dose glucocorticoids and cyclophosphamide. The case illustrates the importance of awareness of ANCA negative AAV among general physicians in order to minimise morbidity and mortality.
Identifiants
pubmed: 38065599
pii: 23/6/630
doi: 10.7861/clinmed.2023-0398
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
630-632Informations de copyright
© Royal College of Physicians 2023. All rights reserved.