Interaction of Bacteriophages with the Immune System: Induction of Bacteriophage-Specific Antibodies.

Antibody Bacteriophage ELISA IgA IgG IgM Immune response Immunization Immunogenicity

Journal

Methods in molecular biology (Clifton, N.J.)

ISSN: 1940-6029

Titre abrégé: Methods Mol Biol

Pays: United States

ID NLM: 9214969

Informations de publication

Date de publication:
2024

Historique:

medline: 9 12 2023

pubmed: 9 12 2023

entrez: 8 12 2023

Statut: ppublish

Résumé

In all cases when a bacteriophage makes a direct contact with a mammalian organism, it may challenge the mammalian immunological system. Its major consequence is the production of antibodies specific to the bacteriophage, particularly IgM, IgG, and IgA as the typical response. Here we present protocols applicable in studies of the ability of bacteriophage to induce specific antibodies; immunization to whole virions or to isolated phage proteins has been included. The protocols have been divided into three parts: purification, immunization, and detection (enzyme-linked immunosorbent assay, ELISA).

Identifiants

DOI: 10.1007/978-1-0716-3523-0_12 PMID: 38066370

pubmed: 38066370

doi: 10.1007/978-1-0716-3523-0_12

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

183-196

Informations de copyright

Références

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