NIR ICG-Enhanced Fluorescence: A Quantitative Evaluation of Bowel Microperfusion and Its Relation to Central Perfusion in Colorectal Surgery.
NIR-ICG-enhanced fluorescence
anastomotic leakage
colorectal cancer
minimally invasive colorectal surgery
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
22 Nov 2023
22 Nov 2023
Historique:
received:
10
10
2023
revised:
01
11
2023
accepted:
13
11
2023
medline:
9
12
2023
pubmed:
9
12
2023
entrez:
9
12
2023
Statut:
epublish
Résumé
To date, no standardized protocols nor a quantitative assessment of the near-infrared fluorescence angiography with indocyanine green (NIR-ICG) are available. The aim of this study was to evaluate the timing of fluorescence as a reproducible parameter and its efficacy in predicting anastomotic leakage (AL) in colorectal surgery. A consecutive cohort of 108 patients undergoing minimally invasive elective procedures for colorectal cancer was prospectively enrolled. The difference between macro and microperfusion (ΔT) was obtained by calculating the timing of fluorescence at the level of iliac artery division and colonic wall, respectively. Subjects with a ΔT ≥ 15.5± 0.5 s had a higher tendency to develop an AL ( The analysis of the timing of fluorescence provides a quantitative, easy evaluation of tissue perfusion. A ΔT/HR interaction ≥832 may be used as a real-time parameter to guide surgical decision making in colorectal surgery.
Sections du résumé
BACKGROUND
BACKGROUND
To date, no standardized protocols nor a quantitative assessment of the near-infrared fluorescence angiography with indocyanine green (NIR-ICG) are available. The aim of this study was to evaluate the timing of fluorescence as a reproducible parameter and its efficacy in predicting anastomotic leakage (AL) in colorectal surgery.
METHODS
METHODS
A consecutive cohort of 108 patients undergoing minimally invasive elective procedures for colorectal cancer was prospectively enrolled. The difference between macro and microperfusion (ΔT) was obtained by calculating the timing of fluorescence at the level of iliac artery division and colonic wall, respectively.
RESULTS
RESULTS
Subjects with a ΔT ≥ 15.5± 0.5 s had a higher tendency to develop an AL (
CONCLUSIONS
CONCLUSIONS
The analysis of the timing of fluorescence provides a quantitative, easy evaluation of tissue perfusion. A ΔT/HR interaction ≥832 may be used as a real-time parameter to guide surgical decision making in colorectal surgery.
Identifiants
pubmed: 38067233
pii: cancers15235528
doi: 10.3390/cancers15235528
pmc: PMC10705733
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : European Research Council (ERC)
ID : contract number 759959
Organisme : the Associazione Italiana per la Ricerca contro il Cancro (AIRC)
ID : contract number 22902
Références
Colorectal Dis. 2013 Apr;15(4):e190-8
pubmed: 23331871
Tech Coloproctol. 2021 Jan;25(1):49-58
pubmed: 32885328
Surg Endosc. 2014 Nov;28(11):3108-18
pubmed: 24912446
Surg Endosc. 2019 May;33(5):1640-1649
pubmed: 30203201
Ann Surg. 2013 Apr;257(4):665-71
pubmed: 23333881
Ann Surg. 2009 Aug;250(2):187-96
pubmed: 19638912
J Laparoendosc Adv Surg Tech A. 2018 Feb;28(2):157-167
pubmed: 29106320
Surgery. 2010 Mar;147(3):339-51
pubmed: 20004450
Ann Surg. 2011 Dec;254(6):907-13
pubmed: 21562405
Dis Colon Rectum. 1990 Mar;33(3):175-9
pubmed: 2178894
Surg Endosc. 2016 Jul;30(7):2736-42
pubmed: 26487209
Int J Colorectal Dis. 2008 Mar;23(3):265-70
pubmed: 18034250
Dis Colon Rectum. 2000 Jan;43(1):76-82
pubmed: 10813128
Colorectal Dis. 2018 Aug;20(8):O226-O234
pubmed: 29751360
Br J Surg. 2015 Jan;102(2):e169-76
pubmed: 25627131
World J Surg. 2019 Mar;43(3):659-695
pubmed: 30426190
Surg Endosc. 2020 Jan;34(1):53-60
pubmed: 30903276
Ann Surg. 2011 May;253(5):890-9
pubmed: 21394013
Colorectal Dis. 2020 Sep;22(9):1147-1153
pubmed: 32189424
Asian J Surg. 2023 Aug 28;:
pubmed: 37648547
Tech Coloproctol. 2018 Jul;22(7):535-540
pubmed: 30097803
J Am Coll Surg. 2009 Feb;208(2):269-78
pubmed: 19228539
Circ Res. 2012 Jul 6;111(2):245-59
pubmed: 22773427
Dis Colon Rectum. 2021 Aug 1;64(8):995-1002
pubmed: 33872284
Int J Med Robot. 2016 Dec;12(4):710-717
pubmed: 26486376
Cancers (Basel). 2022 May 13;14(10):
pubmed: 35626015
Surg Endosc. 2020 Sep;34(9):3897-3907
pubmed: 31586247
Surg Endosc. 2021 Aug;35(8):4321-4331
pubmed: 32856153
Langenbecks Arch Surg. 2010 Nov;395(8):1025-30
pubmed: 20700603
Int J Colorectal Dis. 1994;9(4):211-4
pubmed: 7876727
Surg Endosc. 2020 Oct;34(10):4281-4290
pubmed: 32556696
Tech Coloproctol. 2019 Oct;23(10):973-980
pubmed: 31535238
Asian J Surg. 2023 Sep;46(9):3722-3726
pubmed: 36967350
Tech Coloproctol. 2018 Jan;22(1):15-23
pubmed: 29230591
Surg Endosc. 2017 Mar;31(3):1061-1069
pubmed: 27351656
Int J Colorectal Dis. 2021 Jan;36(1):27-39
pubmed: 32886195
Innov Surg Sci. 2018 Sep 05;3(3):193-201
pubmed: 31579783
Br J Surg. 2005 Jan;92(1):101-6
pubmed: 15635697
Br J Surg. 2015 Apr;102(5):462-79
pubmed: 25703524
J Am Coll Surg. 2015 Jan;220(1):82-92.e1
pubmed: 25451666
Ann Surg. 2013 Jan;257(1):108-13
pubmed: 22968068
Surg Endosc. 2017 Oct;31(10):4184-4193
pubmed: 28281123
Br J Surg. 2011 Dec;98(12):1725-34
pubmed: 21953541
Dis Colon Rectum. 1987 Nov;30(11):867-71
pubmed: 3677962