Recent developments in fluorine-containing pesticides.

To ensure ongoing sustainability, the modern agrochemical industry is faced with enormous challenges. These arise from provision of high-quality food to increasing water use and environmental impact as well as growing world population. The loss of previous agrochemicals due to consumer perception, changing grower needs and everchanging regulatory requirements is higher than the number of active ingredients can being introduced into the crop protection market. Therefore, the development of novel agrochemicals is essential, that can provide improved efficacy and environmental profiles. In this context, introduction of fluorine atoms and fluorine-containing motifs into a molecule is an important method to influence its physicochemical properties. These include for example small difluoro- and trifluoromethyl, or trifluoromethoxy groups at aryl or heterocyclic aryl moieties but also fragments like 2,2,2-trifluoroethoxycarbonyl, trifluoromethylsulfonyl, trifluoroacetyl, as well as the so far unusal rest like heptafluoro-iso-propyl. This review gives an overview of recent developments of fluorine-containing pesticides launched over the past 7 years and describes a selection of current fluorine-containing development candidates. This article is protected by copyright. All rights reserved.

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This article is protected by copyright. All rights reserved.