Disinfectant caps
Catheter-related bloodstream infections (CRBSIs)
Port Protector
disinfectant cap (DCs)
in vitro model
needle-free connectors (NFCs)
Journal
Le infezioni in medicina
ISSN: 2532-8689
Titre abrégé: Infez Med
Pays: Italy
ID NLM: 9613961
Informations de publication
Date de publication:
2023
2023
Historique:
received:
22
08
2023
accepted:
28
10
2023
medline:
11
12
2023
pubmed:
11
12
2023
entrez:
11
12
2023
Statut:
epublish
Résumé
Catheter-related bloodstream infections (CRBSIs) are a major cause of morbidity and mortality among hospitalized patients. Different studies suggest that the use of disinfectant caps (DCs) significantly reduces the rate of CRBSIs. The first purpose of this study is to analyze, through an A know concentration of thirteen different microorganisms was incubated with the sponge drenched in antimicrobial fluid inside DCs and cultured through several assays to investigate the disinfectant effectiveness of some commercially available caps. Disinfectant properties were evaluated under two different conditions: baseline (DCs placed on the needle-free connectors (NFCs) and stress test (DCs directly applied to the catheter hub). Both manufacturers overcame the basal tests (fourteen different assays). Regarding stress tests: the only significant bacterial load was found for Our results confirm what was reported in BD PureHub™ datasheet and add data not previously shown by ICU Medical™. Moreover, no difference was observed between the two manufacturers products: the use of both DCs on NFCs was able to reclaim the catheter lumen. These findings support the routine use of DCs with NFCs, as part of a structured bundle of interventions, to reduce the incidence of CRBSIs.
Sections du résumé
Background
UNASSIGNED
Catheter-related bloodstream infections (CRBSIs) are a major cause of morbidity and mortality among hospitalized patients. Different studies suggest that the use of disinfectant caps (DCs) significantly reduces the rate of CRBSIs. The first purpose of this study is to analyze, through an
Methods
UNASSIGNED
A know concentration of thirteen different microorganisms was incubated with the sponge drenched in antimicrobial fluid inside DCs and cultured through several assays to investigate the disinfectant effectiveness of some commercially available caps. Disinfectant properties were evaluated under two different conditions: baseline (DCs placed on the needle-free connectors (NFCs) and stress test (DCs directly applied to the catheter hub).
Results
UNASSIGNED
Both manufacturers overcame the basal tests (fourteen different assays). Regarding stress tests: the only significant bacterial load was found for
Conclusions
UNASSIGNED
Our results confirm what was reported in BD PureHub™ datasheet and add data not previously shown by ICU Medical™. Moreover, no difference was observed between the two manufacturers products: the use of both DCs on NFCs was able to reclaim the catheter lumen. These findings support the routine use of DCs with NFCs, as part of a structured bundle of interventions, to reduce the incidence of CRBSIs.
Identifiants
pubmed: 38075418
doi: 10.53854/liim-3104-14
pii: 1124-9390_31_4_2023_553-559
pmc: PMC10705867
doi:
Types de publication
Journal Article
Langues
eng
Pagination
553-559Déclaration de conflit d'intérêts
Conflict of interest: The Authors declare no conflicts of interest.
Références
Clin Microbiol Infect. 2015 Apr;21(4):313-22
pubmed: 25753137
Am J Infect Control. 2014 Dec;42(12):1274-7
pubmed: 25465256
Burns. 2017 Aug;43(5):956-964
pubmed: 28139260
Infect Control Hosp Epidemiol. 2022 May;43(5):553-569
pubmed: 35437133
BMC Infect Dis. 2019 Mar 4;19(1):215
pubmed: 30832598
Curr Microbiol. 2022 Oct 17;79(12):361
pubmed: 36253556
J Hosp Infect. 2016 Apr;92(4):346-8
pubmed: 26979872
Am J Infect Control. 2011 May;39(4):309-13
pubmed: 20965611
J Vasc Access. 2020 Nov;21(6):847-853
pubmed: 32056487
Ann Med Health Sci Res. 2014 Sep;4(5):682-6
pubmed: 25328774
Am J Infect Control. 2023 Jul;51(7):827-835
pubmed: 36116679
J Vasc Access. 2022 Jul;23(4):532-537
pubmed: 33618564
Infect Control Hosp Epidemiol. 2015 Jun;36(6):649-55
pubmed: 25732568
Br J Nurs. 2019 Jul 25;28(14):S22-S27
pubmed: 31348703
J Vasc Access. 2023 Jul 18;:11297298231188150
pubmed: 37464763
J Vasc Access. 2023 Nov;24(6):1469-1476
pubmed: 35502147
Intensive Crit Care Nurs. 2023 Aug;77:103442
pubmed: 37120363
Med Intensiva (Engl Ed). 2018 Jan - Feb;42(1):5-36
pubmed: 29406956
Infect Control Hosp Epidemiol. 2006 Jan;27(1):23-7
pubmed: 16418982