Breakthrough SARS-COV-2 infection induces broad anti-viral T cell immunity.
Biological sciences
Immune response
Immunology
Virology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
15 Dec 2023
15 Dec 2023
Historique:
received:
07
08
2023
revised:
11
10
2023
accepted:
13
11
2023
medline:
11
12
2023
pubmed:
11
12
2023
entrez:
11
12
2023
Statut:
epublish
Résumé
Vaccines have curtailed the devastation wrought by COVID-19. Nevertheless, emerging variants result in a high incidence of breakthrough infections. Here we assess the impact of vaccination and breakthrough infection on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T cell immunity. We demonstrate that COVID-19 vaccination induces robust spike-specific T cell responses that, within the CD4
Identifiants
pubmed: 38077128
doi: 10.1016/j.isci.2023.108474
pii: S2589-0042(23)02551-8
pmc: PMC10698266
doi:
Types de publication
Journal Article
Langues
eng
Pagination
108474Informations de copyright
© 2023 The Author(s).
Déclaration de conflit d'intérêts
The authors report no competing interests.
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