Calcium influx promotes PLEKHG4B localization to cell-cell junctions and regulates the integrity of junctional actin filaments.

Journal

Molecular biology of the cell
ISSN: 1939-4586
Titre abrégé: Mol Biol Cell
Pays: United States
ID NLM: 9201390

Informations de publication

Date de publication:
13 Dec 2023
Historique:
medline: 13 12 2023
pubmed: 13 12 2023
entrez: 13 12 2023
Statut: aheadofprint

Résumé

PLEKHG4B is a Cdc42-targeting guanine-nucleotide exchange factor implicated in forming epithelial cell-cell junctions. Here we explored the mechanism regulating PLEKHG4B localization. PLEKHG4B localized to the basal membrane in normal Ca

Identifiants

DOI: 10.1091/mbc.E23-05-0154 PMID: 38088892
pubmed: 38088892
doi: 10.1091/mbc.E23-05-0154
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

mbcE23050154

Auteurs

Komaki Ninomiya (K)

Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.
Laboratory for Histogenetic Dynamics, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.

Kai Ohta (K)

Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.

Ukyo Kawasaki (U)

Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.

Shuhei Chiba (S)

Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.

Takanari Inoue (T)

Department of Cell Biology and Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Erina Kuranaga (E)

Laboratory for Histogenetic Dynamics, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.
Laboratory for Histogenetic Dynamics, Graduate School and Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto 606‑8304, Japan.

Kazumasa Ohashi (K)

Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.
Department of Chemistry, Graduate School of Science, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.

Kensaku Mizuno (K)

Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.
Department of Chemistry, Graduate School of Science, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.

Classifications MeSH