Discharge protocol in acute pancreatitis: an international survey and cohort analysis.

Journal

Scientific reports

ISSN: 2045-2322

Titre abrégé: Sci Rep

Pays: England

ID NLM: 101563288

Informations de publication

Date de publication:
13 Dec 2023

Historique:

received: 04 04 2023

accepted: 27 11 2023

medline: 14 12 2023

pubmed: 14 12 2023

entrez: 13 12 2023

Statut: epublish

Résumé

There are several overlapping clinical practice guidelines in acute pancreatitis (AP), however, none of them contains suggestions on patient discharge. The Hungarian Pancreatic Study Group (HPSG) has recently developed a laboratory data and symptom-based discharge protocol which needs to be validated. (1) A survey was conducted involving all members of the International Association of Pancreatology (IAP) to understand the characteristics of international discharge protocols. (2) We investigated the safety and effectiveness of the HPSG-discharge protocol. According to our international survey, 87.5% (49/56) of the centres had no discharge protocol. Patients discharged based on protocols have a significantly shorter median length of hospitalization (LOH) (7 (5;10) days vs. 8 (5;12) days) p < 0.001), and a lower rate of readmission due to recurrent AP episodes (p = 0.005). There was no difference in median discharge CRP level among the international cohorts (p = 0.586). HPSG-protocol resulted in the shortest LOH (6 (5;9) days) and highest median CRP (35.40 (13.78; 68.40) mg/l). Safety was confirmed by the low rate of readmittance (n = 35; 5%). Discharge protocol is necessary in AP. The discharge protocol used in this study is the first clinically proven protocol. Developing and testifying further protocols are needed to better standardize patients' care.

Identifiants

DOI: 10.1038/s41598-023-48480-z PMID: 38092809

pubmed: 38092809

doi: 10.1038/s41598-023-48480-z

pii: 10.1038/s41598-023-48480-z

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

22109

Subventions

Organisme : János Bolyai Research Scholarship of the Hungarian Academy of Sciences

ID : KA-2019-14, FK131864

Organisme : János Bolyai Research Scholarship of the Hungarian Academy of Sciences

ID : NKFIH OTKA grant (K131996)

Organisme : New National Excellence Program of the Ministry for Innovation and Technology from the source of the National Research, Development and Innovation Fund

ID : ÚNKP-22-5

Organisme : János Bolyai Research Grant

ID : (BO/00648/21/5)

Organisme : New National Excellence Program

ID : UNKP-22-5-SZTE-585

Organisme : EU's Horizon 2020 research and innovation program

ID : 739593

Organisme : New national Excellence Program of the Ministry for Culture and Innovation from the Source of the National Research, Development and Innovation Fund

ID : ÚNKP-22-4-II

Organisme : Ministry of Innovation and Technology of Hungary

ID : TKP2021-EGA-23

Informations de copyright

Références

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