Treatment with psychedelics is psychotherapy: beyond reductionism.


Journal

The lancet. Psychiatry
ISSN: 2215-0374
Titre abrégé: Lancet Psychiatry
Pays: England
ID NLM: 101638123

Informations de publication

Date de publication:
12 Dec 2023
Historique:
received: 17 08 2023
revised: 17 10 2023
accepted: 19 10 2023
medline: 16 12 2023
pubmed: 16 12 2023
entrez: 15 12 2023
Statut: aheadofprint

Résumé

Treatment of psychiatric disorders with psychedelic substances represents one of the most promising current treatment approaches in psychiatry. Since its inception in the 1950s, therapy with psychedelics has been conceptualised as psychedelic-assisted psychotherapy-ie, a form of psychotherapy that uses the profound biological effects of this class of substances as a catalyst for changing thinking, emotions, and behaviour. In this view, the psychotherapy component of the treatment is considered as being of the utmost importance for both the safety and efficacy of the therapy. This conceptualisation has been challenged by the idea that the latest clinical studies suggest that the potential therapeutic effects of psychedelics must be attributed solely to the substance itself, with no role for psychotherapy. Here, accompaniment by therapists is understood as mere psychological support, to maintain the safety of the substance administration. In this Personal View, we contrast these two views and argue that the characterisation of treatment with psychedelics as a biological intervention (with psychological support as a purely safety-related component) represents an outdated and reductionistic dualism that has dominated psychiatric treatment and research for far too long. This discussion has important implications for the study and the regulation of these compounds.

Identifiants

pubmed: 38101439
pii: S2215-0366(23)00363-2
doi: 10.1016/S2215-0366(23)00363-2
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests GG has served as a consultant for Boehringer Ingelheim, the Institute for Quality and Efficiency in Health Care, Janssen-Cilag, Lundbeck, Otsuka, Recordati, Roche, ROVI, Lundbeck, Otsuka, and Recordati. GG has served on the speakers' bureaus of Gedeon Richter, Janssen-Cilag, Lundbeck, Otsuka, and Recordati. GG has received grant support from Boehringer Ingelheim, Lundbeck, and Saladax and is cofounder or shareholder of the Mind and Brain Institute, Brainfoods, OVID Health Systems, and the MIND Foundation. HJ is cofounder and shareholder of OVID Health Systems and the MIND Foundation. GG, MB, LJM, HJ, DJS, and MW are members of the MIND Foundation. All other authors declare no competing interests.

Auteurs

Gerhard Gründer (G)

Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; OVID Health Systems, Berlin, Germany. Electronic address: gerhard.gruender@zi-mannheim.de.

Manuela Brand (M)

Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Lea J Mertens (LJ)

Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Henrik Jungaberle (H)

MIND Foundation, Berlin, Germany; OVID Health Systems, Berlin, Germany.

Laura Kärtner (L)

Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Dennis J Scharf (DJ)

Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Moritz Spangemacher (M)

Department of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

Max Wolff (M)

MIND Foundation, Berlin, Germany; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany.

Classifications MeSH