First Swedish case of fatal equine parasitic encephalitis by Halicephalobus gingivalis.
Encephalitic and nephritic nematodiasis
Horse
Phylogenetic analysis
Zoonosis
Journal
Acta veterinaria Scandinavica
ISSN: 1751-0147
Titre abrégé: Acta Vet Scand
Pays: England
ID NLM: 0370400
Informations de publication
Date de publication:
15 Dec 2023
15 Dec 2023
Historique:
received:
14
07
2023
accepted:
06
12
2023
medline:
16
12
2023
pubmed:
16
12
2023
entrez:
15
12
2023
Statut:
epublish
Résumé
Halicephalobus gingivalis is a nematode with zoonotic potential which can cause fatal opportunistic infections in various mammals. The parasite has never been diagnosed in Sweden, in any species, prior to the presented case. An imported 21-year-old Icelandic mare developed severe neurological signs. The horse was eventually euthanized and submitted for post-mortem examination where severe lesions in the kidneys were noted. Histopathology revealed the presence of H. gingivalis in both kidneys and the brain. Phylogenetic analysis of the parasite determined it to belong to Lineage 1. With the occurrence of H. gingivalis in Sweden, the disease should be added to the list of differential diagnoses in cases with acute onset of neurological disease in both horses and other mammals including humans.
Sections du résumé
BACKGROUND
BACKGROUND
Halicephalobus gingivalis is a nematode with zoonotic potential which can cause fatal opportunistic infections in various mammals. The parasite has never been diagnosed in Sweden, in any species, prior to the presented case.
CASE PRESENTATION
METHODS
An imported 21-year-old Icelandic mare developed severe neurological signs. The horse was eventually euthanized and submitted for post-mortem examination where severe lesions in the kidneys were noted. Histopathology revealed the presence of H. gingivalis in both kidneys and the brain. Phylogenetic analysis of the parasite determined it to belong to Lineage 1.
CONCLUSIONS
CONCLUSIONS
With the occurrence of H. gingivalis in Sweden, the disease should be added to the list of differential diagnoses in cases with acute onset of neurological disease in both horses and other mammals including humans.
Identifiants
pubmed: 38102633
doi: 10.1186/s13028-023-00719-5
pii: 10.1186/s13028-023-00719-5
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
56Informations de copyright
© 2023. The Author(s).
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