Hybrid Shear-thinning Hydrogel Integrating Hyaluronic Acid with ROS-Responsive Nanoparticles.

guest-host chemistry hyaluronic acid reactive oxygen species (ROS) responsive polymer shear-thinning hydrogels triblock copolymer nanoparticles

Journal

Advanced functional materials
ISSN: 1616-301X
Titre abrégé: Adv Funct Mater
Pays: Germany
ID NLM: 101190390

Informations de publication

Date de publication:
01 Aug 2023
Historique:
pmc-release: 01 08 2024
medline: 18 12 2023
pubmed: 18 12 2023
entrez: 18 12 2023
Statut: ppublish

Résumé

Nanoparticle (NP) supra-assembly offers unique opportunities to tune macroscopic hydrogels' mechanical strength, material degradation, and drug delivery properties. Here, synthetic, reactive oxygen species (ROS)-responsive NPs are physically crosslinked with hyaluronic acid (HA) through guest-host chemistry to create shear-thinning NP/HA hydrogels. A library of triblock copolymers composed of poly(propylene sulfide)-

Identifiants

pubmed: 38107427
doi: 10.1002/adfm.202213368
pmc: PMC10723243
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Mariah G Bezold (MG)

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.

Andrew R Hanna (AR)

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.

Bryan R Dollinger (BR)

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.

Prarthana Patil (P)

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.

Fang Yu (F)

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.

Craig L Duvall (CL)

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.

Mukesh K Gupta (MK)

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.

Classifications MeSH