Incubation period of COVID-19: A systematic review and meta-analysis.
Período de incubación de la COVID-19: revisión sistemática y metaanálisis.
Coronavirus
Infectious disease incubation period
Período de incubación de enfermedades infecciosas
Public health
Salud pública
Journal
Revista clinica espanola
ISSN: 1578-1860
Titre abrégé: Rev Clin Esp
Pays: Spain
ID NLM: 8608576
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
24
06
2020
revised:
30
07
2020
accepted:
17
08
2020
medline:
1
2
2021
pubmed:
1
2
2021
entrez:
18
12
2023
Statut:
ppublish
Résumé
The incubation period of COVID-19 helps to determine the optimal duration of the quarantine and inform predictive models of incidence curves. Several emerging studies have produced varying results; this systematic review aims to provide a more accurate estimate of the incubation period of COVID-19. For this systematic review, a literature search was conducted using Pubmed, Scopus/EMBASE, and the Cochrane Library databases, covering all observational and experimental studies reporting the incubation period and published from 1 January 2020 to 21 March 2020.We estimated the mean and 95th percentile of the incubation period using meta-analysis, taking into account between-study heterogeneity, and the analysis with moderator variables. We included seven studies (n = 792) in the meta-analysis. The heterogeneity (I Based on the published data reporting the incubation period of COVID-19, the mean time between exposure and onset of clinical symptoms depended on the statistical model used, and the 95th percentile depended on the mean age of the patients. It is advisable to record sex and age when collecting data in order to analyze possible differential patterns.
Sections du résumé
BACKGROUND AND OBJECTIVE
OBJECTIVE
The incubation period of COVID-19 helps to determine the optimal duration of the quarantine and inform predictive models of incidence curves. Several emerging studies have produced varying results; this systematic review aims to provide a more accurate estimate of the incubation period of COVID-19.
METHODS
METHODS
For this systematic review, a literature search was conducted using Pubmed, Scopus/EMBASE, and the Cochrane Library databases, covering all observational and experimental studies reporting the incubation period and published from 1 January 2020 to 21 March 2020.We estimated the mean and 95th percentile of the incubation period using meta-analysis, taking into account between-study heterogeneity, and the analysis with moderator variables.
RESULTS
RESULTS
We included seven studies (n = 792) in the meta-analysis. The heterogeneity (I
CONCLUSION
CONCLUSIONS
Based on the published data reporting the incubation period of COVID-19, the mean time between exposure and onset of clinical symptoms depended on the statistical model used, and the 95th percentile depended on the mean age of the patients. It is advisable to record sex and age when collecting data in order to analyze possible differential patterns.
Identifiants
pubmed: 38108501
pii: S0014-2565(20)30240-X
doi: 10.1016/j.rce.2020.08.005
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
spa
Pagination
109-117Informations de copyright
Copyright © 2020 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.