Mortality Associated With Proportionality of Secondary Mitral Regurgitation After Transcatheter Mitral Valve Repair: North American Mitraclip for Functional Mitral Regurgitation Registry.

The association, if any, between the effective regurgitant orifice (EROA) to left ventricular end-diastolic volume (LVEDV) ratio and 1-year mortality is controversial in patients undergoing mitral transcatheter edge-to-edge repair (m-TEER) with the MitraClip™ system. This study's objective was to determine the association between EROA/LVEDV and 1-year mortality among patients undergoing m-TEER with MitraClip™.In patients with severe secondary (functional) mitral regurgitation, we analyzed registry data from 11 centers using generalized linear models with the generalized estimating equations approach. We studied 525 patients with secondary MR who underwent m-TEER. Most patients were male (63%) and were NYHA class III (61%) or IV (21%). Mitral regurgitation was caused by ischemic cardiomyopathy in 51% of patients. EROA/LVEDV values varied widely with median=0.19 mm

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Copyright © 2023. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: D Scott Lim reports a relationship with Abbott that includes: funding grants. D Scott Lim reports a relationship with Boston Scientific Corp that includes: funding grants. D Scott Lim reports a relationship with Corvia Medical that includes: funding grants. D Scott Lim reports a relationship with Edwards Lifesciences Corporation that includes: funding grants. D Scott Lim reports a relationship with Medtronic Inc that includes: funding grants. D Scott Lim reports a relationship with Trisol that includes: funding grants. D Scott Lim reports a relationship with Philips that includes: consulting or advisory. D Scott Lim reports a relationship with Valgen that includes: consulting or advisory. D Scott Lim reports a relationship with Venus that includes: consulting or advisory. Evelio Rodriguez reports a relationship with Abbott that includes: consulting or advisory, funding grants, and speaking and lecture fees. Firas E Zahr reports a relationship with Medtronic Inc that includes: board membership, consulting or advisory, and funding grants. Firas E Zahr reports a relationship with Edwards Lifesciences Corporation that includes: funding grants. Firas E Zahr reports a relationship with SIEMENS that includes: funding grants. Gorav Ailawadi reports a relationship with Medtronic Inc that includes: consulting or advisory. Gorav Ailawadi reports a relationship with Abbott that includes: consulting or advisory. Gorav Ailawadi reports a relationship with Edwards Lifesciences Corporation that includes: consulting or advisory. Gorav Ailawadi reports a relationship with Gore that includes: consulting or advisory. Gorav Ailawadi reports a relationship with Anteris that includes: consulting or advisory. Gorav Ailawadi reports a relationship with AtriCure Inc that includes: consulting or advisory. Gorav Ailawadi reports a relationship with CryoLife that includes: consulting or advisory. Gorav Ailawadi reports a relationship with Philips that includes: consulting or advisory. Gorav Ailawadi reports a relationship with Johnson & Johnson that includes: consulting or advisory. Jason H Rogers reports a relationship with Abbott that includes: consulting or advisory and funding grants. Jason H Rogers reports a relationship with Boston Scientific Corp that includes: consulting or advisory and funding grants. Jason H Rogers reports a relationship with Baylis Medical Company, Inc. that includes: consulting or advisory. Lily Chen reports a relationship with Philips that includes: consulting or advisory. Lily Chen reports a relationship with Abbott that includes: consulting or advisory. Lily Chen reports a relationship with Akura Medical that includes: consulting or advisory. Mani A Vannan reports a relationship with Abbott that includes: funding grants and speaking and lecture fees. Neal M Duggal reports a relationship with Medtronic Inc that includes: consulting or advisory. Nishtha Sodhi reports a relationship with Medtronic Inc that includes: consulting or advisory. Nishtha Sodhi reports a relationship with Boston Scientific Corp that includes: consulting or advisory. Paul Sorajja reports a relationship with 4C Medical Technologies Inc that includes: consulting or advisory. Paul Sorajja reports a relationship with Anteris that includes: consulting or advisory. Paul Sorajja reports a relationship with Abbott that includes: consulting or advisory. Paul Sorajja reports a relationship with Boston Scientific Corp that includes: consulting or advisory. Paul Sorajja reports a relationship with Edwards Lifesciences Corporation that includes: consulting or advisory. Paul Sorajja reports a relationship with Evolution Medical that includes: consulting or advisory. Paul Sorajja reports a relationship with Foldax that includes: consulting or advisory. Paul Sorajja reports a relationship with GLG that includes: consulting or advisory. Paul Sorajja reports a relationship with Medtronic Inc that includes: consulting or advisory. Paul Sorajja reports a relationship with Philips that includes: consulting or advisory. Paul Sorajja reports a relationship with SIEMENS that includes: consulting or advisory. Paul Sorajja reports a relationship with Shifamed that includes: consulting or advisory. Paul Sorajja reports a relationship with WL Gore that includes: consulting or advisory. Paul Sorajja reports a relationship with vDyne that includes: consulting or advisory. Paul Sorajja reports a relationship with xDot that includes: consulting or advisory. Pradeep K Yadav reports a relationship with Edwards Lifesciences Corporation that includes: consulting or advisory and speaking and lecture fees. Pradeep K Yadav reports a relationship with Abbott that includes: consulting or advisory and speaking and lecture fees. Pradeep K Yadav reports a relationship with Boston Scientific Corp that includes: consulting or advisory and speaking and lecture fees. Pradeep K Yadav reports a relationship with Dasi Simulations that includes: board membership. Scott M Chadderdon reports a relationship with Medtronic Inc that includes: consulting or advisory. Scott M Chadderdon reports a relationship with Edwards Lifesciences Corporation that includes: consulting or advisory. Scott M Chadderdon reports a relationship with GE Healthcare that includes: funding grants. Stanley J Chetcuti reports a relationship with Medtronic Inc that includes: consulting or advisory and funding grants. Stanley J Chetcuti reports a relationship with Boston Scientific Corp that includes: consulting or advisory and funding grants. Stanley J Chetcuti reports a relationship with Jena that includes: funding grants. Stanley J Chetcuti reports a relationship with Abbott that includes: funding grants. Stanley J Chetcuti reports a relationship with Edwards Lifesciences Corporation that includes: funding grants. Stanley J Chetcuti reports a relationship with Gore that includes: funding grants.