Decreased serum creatinine to cystatin C ratio is associated with low tongue pressure.

creatinine-to-cystatin C ratio oral hypofunction sarcopenia screening tongue pressure

Journal

Geriatrics & gerontology international
ISSN: 1447-0594
Titre abrégé: Geriatr Gerontol Int
Pays: Japan
ID NLM: 101135738

Informations de publication

Date de publication:
18 Dec 2023
Historique:
revised: 21 11 2023
received: 28 06 2023
accepted: 28 11 2023
medline: 19 12 2023
pubmed: 19 12 2023
entrez: 19 12 2023
Statut: aheadofprint

Résumé

Tongue strength plays an important role in the process of food intake, and low tongue pressure has been associated with aspiration pneumonia, cognitive decline, and mortality. However, special equipment for tongue pressure measurement is uncommon in general practice. Recently, the serum creatinine-to-cystatin C (Cr/CysC) ratio has been validated as a marker of muscle volume mass. Thus, we aimed to investigate the association of the serum Cr/CysC ratio with tongue pressure in a cross-sectional study. This single-center, cross-sectional study enrolled 73 participants (mean age, 71.7 years; men, 49.3%) who regularly attended the hospital for treatment of chronic disease. A tongue pressure of <30 kPa was defined as low tongue pressure. We evaluated the relationships between the serum Cr/CysC ratio and tongue pressure using multiple regression analysis. The serum Cr/CysC ratio was correlated with tongue pressure (R We demonstrated that a decreased serum Cr/CysC ratio was associated with a higher risk of low tongue pressure. Our findings suggest that this simple serum surrogate marker may be a first step toward an intervention for oral function by general practitioners. Geriatr Gerontol Int 2023; ••: ••-••.

Identifiants

pubmed: 38110724
doi: 10.1111/ggi.14780
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Japan Society for the Promotion of Science
ID : 19K10467
Organisme : Japan Society for the Promotion of Science
ID : 20K19663
Organisme : Japan Society for the Promotion of Science
ID : 23K16232
Organisme : Yazuya Food and Health Research Foundation

Informations de copyright

© 2023 The Authors. Geriatrics & Gerontology International published by John Wiley & Sons Australia, Ltd on behalf of Japan Geriatrics Society.

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Auteurs

Yuji Komorita (Y)

Division of General Internal Medicine, Kyushu Dental University, Kitakyushu, Japan.
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Hitoshi Ide (H)

Division of General Internal Medicine, Kyushu Dental University, Kitakyushu, Japan.
Diabetes Center, Hakujyuji Hospital, Fukuoka, Japan.

Masahito Yoshinari (M)

Yoshinari Naika Clinic, Fukuoka, Japan.

Yuko Ohta (Y)

Division of General Internal Medicine, Kyushu Dental University, Kitakyushu, Japan.

Ikuo Nakamichi (I)

Division of General Internal Medicine, Kyushu Dental University, Kitakyushu, Japan.

Ritsuko Fujisawa (R)

Division of General Internal Medicine, Kyushu Dental University, Kitakyushu, Japan.

Wataru Fujii (W)

Yoshinari Naika Clinic, Fukuoka, Japan.
Unit of Interdisciplinary Promotion School of Oral Health Sciences, Kyushu Dental University, Kitakyushu, Japan.

Masayo Fukuhara (M)

Division of General Internal Medicine, Kyushu Dental University, Kitakyushu, Japan.

Classifications MeSH