Priapism in a 31-Year-Old Male With Paranoid Schizophrenia.
alpha-1 adrenergic agonist
medication side effects
nonischemic priapism
paranoid schizophrenia
second-generation antipsychotics
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
accepted:
17
11
2023
medline:
19
12
2023
pubmed:
19
12
2023
entrez:
19
12
2023
Statut:
epublish
Résumé
Priapism is a painful and emergent side effect that has been linked to some antipsychotics and other psychiatric medications, most often trazodone. This is thought to be due to some level of alpha-1 adrenergic blockade by these medications. Aripiprazole is an atypical antipsychotic with notably weak alpha-1 adrenergic antagonism. Thus, we report on a unique case of aripiprazole-induced priapism in a patient with schizophrenia and recurrent episodes of antipsychotic-induced priapism. This study offers insight into the potential mechanism of aripiprazole-induced priapism and offers alternative medications, such as olanzapine and lumateperone, to treat the patient's ongoing psychotic disorder.
Identifiants
pubmed: 38111440
doi: 10.7759/cureus.48978
pmc: PMC10726096
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e48978Informations de copyright
Copyright © 2023, Espiridion et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.