The ethyl acetate extract of

Anticancer Gemcitabine PANC-1 cells RAS/MEK pathways Vernonia amygdalina

Journal

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
ISSN: 1319-0164
Titre abrégé: Saudi Pharm J
Pays: Saudi Arabia
ID NLM: 9705695

Informations de publication

Date de publication:
Jan 2024
Historique:
received: 18 08 2023
accepted: 12 11 2023
medline: 19 12 2023
pubmed: 19 12 2023
entrez: 19 12 2023
Statut: ppublish

Résumé

Individuals diagnosed with cancer often turn to the use of herbal remedies with the intention of treating and ameliorating the condition, impeding the progression of metastasis, enhancing immune function, mitigating stress, and inducing relaxation. Recently, medicinal plants were combined with conventional chemotherapy to decrease the side effects and increase the effectiveness of chemotherapy. This study showed the effectiveness of gemcitabine (Gem) was significantly increased after being used together with ethyl acetate extract obtained from

Identifiants

pubmed: 38111670
doi: 10.1016/j.jsps.2023.101872
pii: S1319-0164(23)00367-5
pmc: PMC10727942
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101872

Informations de copyright

© 2023 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Poppy Anjelisa Zaitun Hasibuan (PAZ)

Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Indonesia.

Jane Melita Keliat (JM)

Department of Pharmaceutical and Food Analysis, Faculty of Vocational, Universitas Sumatera Utara, Indonesia.

Muhammad Fauzan Lubis (MF)

Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Sumatera Utara, Indonesia.

Annisa Nasution (A)

Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Indonesia.

Classifications MeSH