Combined clinical and radiological remission of rectovaginal fistulas using fractional CO2 vaginal laser: a case series and medium-term follow-up.

CO2 laser Rectovaginal fistula Treatment

Journal

BMC research notes
ISSN: 1756-0500
Titre abrégé: BMC Res Notes
Pays: England
ID NLM: 101462768

Informations de publication

Date de publication:
19 Dec 2023
Historique:
received: 07 08 2023
accepted: 11 12 2023
medline: 20 12 2023
pubmed: 20 12 2023
entrez: 20 12 2023
Statut: epublish

Résumé

Despite the advances in surgical and clinical approaches, there is no consensus regarding the best line of treatment from rectovaginal fistula (RVF). Faced with a challenging scenario in the approach of RVF, the fractional CO2 laser receives attention as a possible form of treatment. A single-center, prospective, open-label study evaluating the effectiveness and safety of laser therapy for RVF treatment. The total of 15 patients was recruited at the Juiz de Fora University Hospital between August 2018 and July 2022. Inclusion criteria were presence of clinically suspects RVF of any etiology confirmed by pelvic magnetic resonance image (MRI) and gynecological examination. Five fractional CO2 laser sessions with monthly interval followed by complete evaluation through clinical examination and pelvic MRI were performed for all patients after the completion of treatment. Analysis of sexual function before and after the treatment was performed using Female Sexual Quotient (FSQ). The evaluation through physical examination showed no persistent inflammatory signs in the vagina for all patients. Additionally, 10 of out 15 (67.7%) patients achieved clinical remission of RVF symptoms, while 33.3% patients reported significant improvement. Of note, five patients who did not have previous sexual activity returned to regular sexual activity while seven patients who have baseline sexual activity had improvement in their sexual function as assessed by the FSQ. Three out of four ostomized patients had their ostomy reversed and remained without complains. All six patients with RVF secondary to Crohn's disease reported a marked improvement in symptoms and sexual function. In seven (47%) patients radiological remission was confirmed by pelvic MRI. CO2 fractional laser can be considered a promising and safe therapeutic alternative for the management of RVF.

Identifiants

pubmed: 38115124
doi: 10.1186/s13104-023-06666-8
pii: 10.1186/s13104-023-06666-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

371

Informations de copyright

© 2023. The Author(s).

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Auteurs

Denise Gasparetti Drumond (DG)

Department of Surgery, Faculty of Medicine, Universidade Federal de Juiz de Fora, Rua Doutor Waldyr Lorentz, 11, Juiz de Fora, MG, CEP: 36.037-752, Brazil. denise.drumond@bol.com.br.

Camila de Moraes Sarmento Condé (CMS)

Universidade Federal de Juiz de Fora, Juiz de Fora, Brazil.

Júlio Maria da Fonseca Chebli (JMDF)

Department of Medicine, Faculty of Medicine, Inflammatory Bowel Disease Center, Universitary Hospital, Universidade Federal de Juiz de Fora, Juiz de Fora, Brazil.

Liliana Andrade Chebli (LA)

Department of Medicine, Faculty of Medicine, Inflammatory Bowel Disease Center, Universitary Hospital, Universidade Federal de Juiz de Fora, Juiz de Fora, Brazil.

Samuel Drumond Esperança (SD)

Hospital Israelita Albert Einstein, São Paulo, Brazil.

Neila Maria de Góis Speck (NMG)

Department of Gynecology, Universidade Federal de São Paulo, São Paulo, Brazil.

Classifications MeSH