[EXCESS WEIGHT AND SOCIODEMOGRAPHIC RISK FACTORS FOR SARS-COV-2 INFECTION IN ISRAEL].


Journal

Harefuah
ISSN: 0017-7768
Titre abrégé: Harefuah
Pays: Israel
ID NLM: 0034351

Informations de publication

Date de publication:
Dec 2023
Historique:
medline: 21 12 2023
pubmed: 21 12 2023
entrez: 21 12 2023
Statut: ppublish

Résumé

Studies to date have demonstrated an increased prevalence of obesity and low socioeconomic status (SES( among people with confirmed cases of COVID-19, and low SES has been linked to obesity. Our goal was to better understand the important relationship between body weight and sociodemographic variables affecting the COVID-19 burden. We conducted a cross-sectional study of subjects presenting to Israel's largest emergency department and their odds for positive SARS-CoV-2 virus PCR testing during the first wave of the pandemic. We found that as BMI rises, as compared to normal weight, it is associated with increasing odds for testing positive, independently of age, gender, SES and population density (BMI 25-29.9 kg/m2: OR = 1.42, 95% CI 1.07 - 1.90; BMI 30-34.9 kg/m2: OR = 1.50, 95% CI 1.06 - 2.11; BMI ≥ 35 kg/m2: OR = 1.61, 95% CI 1.02 - 2.46). Furthermore, male gender, low SES and high population density are also associated with excess risk for positive test results independently of body weight. Understanding these risk factors for infection and how they might interplay can help the medical community develop approaches to protect at-risk groups from infection and severe disease secondary to seasonal and pandemic viral infections.

Sections du résumé

BACKGROUND BACKGROUND
Studies to date have demonstrated an increased prevalence of obesity and low socioeconomic status (SES( among people with confirmed cases of COVID-19, and low SES has been linked to obesity.
OBJECTIVES OBJECTIVE
Our goal was to better understand the important relationship between body weight and sociodemographic variables affecting the COVID-19 burden.
METHODS METHODS
We conducted a cross-sectional study of subjects presenting to Israel's largest emergency department and their odds for positive SARS-CoV-2 virus PCR testing during the first wave of the pandemic.
RESULTS RESULTS
We found that as BMI rises, as compared to normal weight, it is associated with increasing odds for testing positive, independently of age, gender, SES and population density (BMI 25-29.9 kg/m2: OR = 1.42, 95% CI 1.07 - 1.90; BMI 30-34.9 kg/m2: OR = 1.50, 95% CI 1.06 - 2.11; BMI ≥ 35 kg/m2: OR = 1.61, 95% CI 1.02 - 2.46). Furthermore, male gender, low SES and high population density are also associated with excess risk for positive test results independently of body weight.
CONCLUSIONS CONCLUSIONS
Understanding these risk factors for infection and how they might interplay can help the medical community develop approaches to protect at-risk groups from infection and severe disease secondary to seasonal and pandemic viral infections.

Identifiants

pubmed: 38126151

Types de publication

English Abstract Journal Article

Langues

heb

Sous-ensembles de citation

IM

Pagination

666-671

Auteurs

Hadar Milloh Raz (H)

Sackler Faculty of Medicine, University of Tel Aviv, Tel Aviv, Israel, Division of Endocrinology, Diabetes and Metabolism, Chaim Sheba Medical Center, Tel-HaShomer, Ramat-Gan, Israel.

Miriam Ben-Hamo (M)

Sackler Faculty of Medicine, University of Tel Aviv, Tel Aviv, Israel, Arrow Program for Medical Research Education, Sheba Medical Center, Tel-Hashomer, Israel.

Noga Minsky (N)

Sackler Faculty of Medicine, University of Tel Aviv, Tel Aviv, Israel, Division of Endocrinology, Diabetes and Metabolism, Chaim Sheba Medical Center, Tel-HaShomer, Ramat-Gan, Israel, Arrow Program for Medical Research Education, Sheba Medical Center, Tel-Hashomer, Israel.

Galia Zacay (G)

Sackler Faculty of Medicine, University of Tel Aviv, Tel Aviv, Israel, Department of Family Medicine, Meuhedet Health Maintenance Organization, Tel Aviv 6203854, Israel.

Gabriella Segal-Lieberman (G)

Sackler Faculty of Medicine, University of Tel Aviv, Tel Aviv, Israel, Division of Endocrinology, Diabetes and Metabolism, Chaim Sheba Medical Center, Tel-HaShomer, Ramat-Gan, Israel, Arrow Program for Medical Research Education, Sheba Medical Center, Tel-Hashomer, Israel.

Classifications MeSH