Evaluation of a phosphate kinetics model in hemodialysis therapy-Assessment of the temporal robustness of model predictions.
compartment modeling
dialysis
hyperphosphatemia
kinetics
phosphate
Journal
Physiological reports
ISSN: 2051-817X
Titre abrégé: Physiol Rep
Pays: United States
ID NLM: 101607800
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
revised:
04
12
2023
received:
21
04
2023
accepted:
04
12
2023
medline:
22
12
2023
pubmed:
22
12
2023
entrez:
21
12
2023
Statut:
ppublish
Résumé
In-depth understanding of intra- and postdialytic phosphate kinetics is important to adjust treatment regimens in hemodialysis. We aimed to modify and validate a three-compartment phosphate kinetic model to individual patient data and assess the temporal robustness. Intradialytic phosphate samples were collected from the plasma and dialysate of 12 patients during two treatments (HD1 and HD2). 2-h postdialytic plasma samples were collected in four of the patients. First, the model was fitted to HD1 samples from each patient to estimate the mass transfer coefficients. Second, the best fitted model in each patient case was validated on HD2 samples. The best model fits were determined from the coefficient of determination (R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e15899Subventions
Organisme : Novo Nordisk Foundation Center for Basic Metabolic Research (NovoNordisk Foundation Center for Basic Metabolic Research)
ID : OL8201
Informations de copyright
© 2023 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.
Références
Agar, B. U., Akonur, A., Lo, Y. C., Cheung, A. K., & Leypoldt, J. K. (2011). Kinetic model of phosphorus mobilization during and after short and conventional hemodialysis. Clinical Journal of the American Society of Nephrology, 6(12), 2854-2860.
Akimbekov, N. S., Digel, I., Sherelkhan, D. K., & Razzaque, M. S. (2022). Vitamin D and phosphate interactions in health and disease. Advances in Experimental Medicine and Biology, 1362, 37-46.
Andersen, M., & Bangsgaard, K. O. (2023). Mathematical biology analytical solution of phosphate kinetics for hemodialysis. J Math Biol, 87(1), 1-22. https://doi.org/10.1007/s00285-023-01942-4
Barreto, F. C., Barreto, D. V., Massy, Z. A., & Drüeke, T. B. (2019). Strategies for phosphate control in patients with CKD. Kidney Int Rep, 4(8), 1043-1056. https://doi.org/10.1016/j.ekir.2019.06.002
Carson, E., & Cobelli, C. (2014). Modeling methodology for physiology and medicine (2nd ed., pp. 1-82). Elsevier.
Clark, W. R., Roncod, E., & Rochac, C. (2007). Solute removal by hollow-fiber dialyzers. Contributions to Nephrology, 158, 20-33.
Cobelli, C., & Carson, E. (2019). Modeling the system. In Introduction to modeling in physiology and medicine (2nd ed., pp. 85-169). Academic Press.
Costanzo LS. Cellular physiology. 6th ed. Physiology. Philadelphia; 2018. 1-310 p.
Cozzolino, M., Dusso, A. S., & Slatopolsky, E. (2001). Role of calcium-phosphate product and bone-associated proteins on vascular calcification in renal failure. J Am Soc Nephrol, 12(11), 2511-2516.
Debowska, M., Poleszczuk, J., Wojcik-Zaluska, A., Ksiazek, A., & Zaluska, W. (2015). Phosphate kinetics during weekly cycle of hemodialysis sessions: Application of mathematical modeling. Artificial Organs, 39(12), 1005-1014.
Desoi, C. A., & Umans, J. G. (1993). Phosphate kinetics during high-flux hemodialysis. J Am Soc Nephrol., 4(5), 1214-1218.
Eknoyan, G., Lameire, N., Kai-Uwe, E., Kasiske, B. L., Wheeler, D. C., Abboud, O. I., et al. (2013). KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International. Supplement, 3(1), 1-163.
Excel-rsq-function [Internet]. [2023]. Available from: https://learn.microsoft.com/en-us/office/troubleshoot/excel/statistical-functions-rsq
Farrell, P. C. (1983). Kinetic modeling: Applications in renal and related diseases. Kidney International, 24(4), 487-495.
Ford, M. L., Tomlinson, L. A., Chapman, T. P. E., Rajkumar, C., & Holt, S. G. (2010). Aortic stiffness is independently associated with rate of renal function decline in chronic kidney disease stages 3 and 4. Hypertension, 55, 1110-1115.
Fouque, D., Roth, H., Darne, B., Jean-bouchet, L., Daugas, E., Drüeke, T. B., et al. (2018). Achievement of kidney disease : Improving global outcomes mineral and bone targets between 2010 and 2014 in incident dialysis patients in France: The photo-Graphe3 study. Clinical Kidney Journal, 11(1), 73-79.
Galvao, J. F. D. B., Nagode, L. A., Schenck, P. A., & Chew, D. J. (2013). State of the art review fibroblast growth factor-23 interactions in chronic kidney disease. Journal of Veterinary Emergency and Critical Care, 23(2), 134-162.
Goodman, W. G. (2004). The consequences of uncontrolled secondary hyperparathyroidism and its treatment in chronic kidney disease. Seminars in Dialysis, 17(3), 209-216.
Heaf, J., & Jensen, S. (1994). Normalised cellular clerance of creatinine, urea and phosphate. Nephron, 67(2), 197-202.
Heaf, J. G., Jensen, S. B., Jensen, K., Ali, S., & von Jessen, F. (1998). The cellular clearance theory does not explain the post-dialytic small molecule rebound. Scandinavian Journal of Urology and Nephrology, 32(5), 350-355.
Iwasawa, H., Nakao, T., Matsumoto, H., Okada, T., & Nagaoka, Y. (2013). Phosphate handling by end-stage kidneys and benefits of residual renal function on phosphate removal in patients on haemodialysis. Nephrology, 18, 285-291.
Kuhlmann, M. K. (2006). Management of hyperphosphatemia. Hemodialysis International, 10(4), 338-345.
Kuhlmann, M. K. (2010). Phosphate elimination in modalities of hemodialysis and peritoneal dialysis. Blood Purification, 29(2), 137-144.
Laursen, S. H., Buus, A. A., Jensen, M. H., Vestergaard, P., & Hejlesen, O. K. (2015). Distribution volume assessment compartment modelling: Theoretic phosphate kinetics in steady state Hemodialys patients. The International Journal of Artificial Organs, 38(11), 580-587.
Laursen, S. H., Vestergaard, P., & Hejlesen, O. K. (2017). Phosphate kinetic models in hemodialysis: A systematic review. American Journal of Kidney Diseases, 71(1), 75-90.
Leypoldt, J. K., Agar, B. U., Akonur, A., Gellens, M. E., & Culleton, B. F. (2012). Steady state phosphorus mass balance model during hemo_dialysis based on a pseudo one-compartment kinetic model. The International Journal of Artificial Organs, 35(11), 969-980.
Lim, V. S., Flanigan, M. J., & Fangman, J. (1990). Effect of hematocrit on solute removal during high efficiency hemodialysis. Kidney International, 37(6), 1557-1562.
Llach, F., & Forero, F. V. (2001). Secondary hyperparathyroidism in chronic renal failure: Pathogenic and clinical aspects. American Journal of Kidney Diseases, 38(Suppl. 5), 20-33.
London, G. M. (2018). Arterial stiffness in chronic kidney disease and end-stage renal disease. Blood Purification, 45, 154-158.
Maasrani, M., Jaffrin, M. Y., Fischbach, M., & Boudailliez, B. (1995). Urea, creatinine and phosphate kinetic modeling during dialysis: Application to pediatric hemodialysis. The International Journal of Artificial Organs, 18(3), 122-129.
Martin, K. J., Floege, J., & Ketteler, M. (2010). Bone and mineral metabolism in chronic kidney disease. In Comprehensive clinical nephrology (4th ed., pp. 969-984). Saunders/Elsevier.
Mizobuchi, M., Towler, D., & Slatopolsky, E. (2009). Vascular calcification: The killer of patients with chronic kidney disease. J Am Soc Nephrol, 20(20), 1453-1464.
Moe, S. (2010). Chronic kidney disease-mineral bone disorder. In Chronic kidney disease, dialysis, and transplantation (3rd ed., pp. 98-114). Saunders/Elsevier.
Moe, S., Drüeke, T., Cunningham, J., Goodman, W., Martin, K., Olgaard, K., Ott, S., Sprague, S., Lameire, N., Eknoyan, G., & Kidney Disease: Improving Global Outcomes (KDIGO). (2006). Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney International, 69, 1945-1953.
Nadkarni, G. N., & Uribarri, J. (2014). Phosphorus and the kidney: What is known and what is needed. Advances in Nutrition, 5(1), 98-103.
Perwad, F., Zhang, M. Y. H., Tenenhouse, H. S., & Portale, A. A. (2007). Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha -hydroxylase expression in vitro. American Journal of Physiology - Renal Physiology, 293(293), 1577-1583.
Pogglitsch, H., Estelberger, W., Petek, W., Zitta, S., & Ziak, E. (1989). Relationship between generation and plasma concentration of anorganic phosphorus. In vivo studies on dialysis patients and in vitro studies on erythrocytes. The International Journal of Artificial Organs, 12(8), 524-532.
Pogglitsch, H., Petek, W., Ziak, E., Sterz, F., & Holzer, H. (1984). Phosphorus kinetics during haemodialysis and haemofiltration. Proc EDTA., 21, 461-467.
Ronco, C., Ghezzib, P. M., Metrya, G., Spittle, M. B., Rodighiero, A., Mariapia Milan, M., Zanella, M., La, G. G., et al. (2001). Effects of hematocrit and blood flow distribution on solute clearance in hollow-fiber Hemodialyzers. Nephron, 89, 243-250.
Ruggeri, A., Giove, S., & Nordio, M. (1997). New models of phosphate kinetics in dialysis patients. Conf Proc IEEE Eng Med Biol Soc p. 2132-4.
Spalding, E. M., Chamney, P. W., & Farrington, K. (2002). Phosphate kinetics during hemodialysis: Evidence for biphasic regulation. Kidney International, 61(2), 655-667.
Sugisaki, H., Onohara, M., & Kunitomo, T. (1982). Dynamic behavior of plasma phosphate in chronic dialysis patients. Trans Am Soc Artif Intern Organs, 28(1), 302-307.
Sugisaki, H., Onohara, M., & Kunitomo, T. (1983). Phosphate in dialysis patients. Am Soc Artif Intern Organs, 29, 38-43.
Suranyi, M., & Chow, J. S. F. (2010). Review: Anticoagulation for haemodialysis. Nephrology, 15(4), 386-392.
Tan, J., Li, Y., Wu, Z., & Zhao, J. (2018). Therapeutics and clinical risk management risk of hip fracture in patients on dialysis or kidney transplant: A meta-analysis of 14 cohort studies. Therapeutics and Clinical Risk Management, 1747-55, 1747-1755.
Upton, G., & Cook, I. (2014). A Dictonary of statistics (3rd ed.). Oxford University Press.
Vikrant, S., & Parashar, A. (2016). Prevalence and severity of disordered mineral metabolism in patients with chronic kidney disease: A study from a tertiary care hospital in India. Indian J Endocrinol Metab, 20(4), 460-467.
Wang, M., Li, H., Liao, H., Yu, Y., You, L., Zhu, J., Huang, B., Yuan, L., Hao, C., & Chen, J. (2012 Jul). Phosphate removal model: An observational study of low-flux dialyzers in conventional hemodialysis therapy. Hemodialysis International, 16(3), 363-376.
Watson, P., Watson, I., & Batt, R. (1980). Total body water volumes for adult males and females estimated from simple anthropometric measurements. The American Journal of Clinical Nutrition, 33(1), 27-39.
Wheeler, D. C., & Winkelmayer, W. C. (2017). Kdigo 2017 clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-Mineral and bone disorder (CKD-MBD). Kidney International. Supplement, 7, 1-59.
Zhang, W., Du, Q., Xiao, J., Bi, Z., Yu, C., Ye, Z., et al. (2021). Modification and validation of the phosphate removal model: A multicenter study. Kidney & Blood Pressure Research, 46, 53-62.