Do Patients with Chronic Spinal Pain and Comorbid Insomnia Have More Features of Central Sensitization? A Case-Control Study.

central sensitization chronic pain chronic spinal pain insomnia polysomnography

Journal

Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525

Informations de publication

Date de publication:
12 Dec 2023
Historique:
received: 10 10 2023
revised: 26 11 2023
accepted: 07 12 2023
medline: 22 12 2023
pubmed: 22 12 2023
entrez: 22 12 2023
Statut: epublish

Résumé

Chronic spinal pain (CSP) is a major public health problem worldwide, frequently related to sleep problems. Central sensitization (CS) may worsen the clinical picture of CSP patients with insomnia. The aim of this study was to compare self-reported and objectively measured clinical outcomes between insomniac CSP patients with comorbid insomnia with and without symptoms of CS. A case-control study on baseline self-reported sleep, functioning, and psychological distress through online questionnaires. Objective sleep and physical activity parameters and pressure pain thresholds (PPTs) were assessed through polysomnography, actigraphy, and digital algometry, respectively. Independent sample t-test and Mann-Whitney U tests were used to examine possible differences in the outcome measures between the groups. Data from 123 participants were included and revealed no statistically significant group for objective sleep and physical activity parameters. The CS group, however, presented with worse self-reported sleep (quality sleep, insomnia severity, and dysfunctional beliefs about sleep), increased mental and physical fatigue, and higher psychological distress (anxiety and depressive symptoms), and reported lower PPTs. symptoms of CS may influence perceived sleep and affect functional health and well-being perception but do not seem to affect objective sleep and physical activity.

Sections du résumé

BACKGROUND BACKGROUND
Chronic spinal pain (CSP) is a major public health problem worldwide, frequently related to sleep problems. Central sensitization (CS) may worsen the clinical picture of CSP patients with insomnia. The aim of this study was to compare self-reported and objectively measured clinical outcomes between insomniac CSP patients with comorbid insomnia with and without symptoms of CS.
METHODS METHODS
A case-control study on baseline self-reported sleep, functioning, and psychological distress through online questionnaires. Objective sleep and physical activity parameters and pressure pain thresholds (PPTs) were assessed through polysomnography, actigraphy, and digital algometry, respectively. Independent sample t-test and Mann-Whitney U tests were used to examine possible differences in the outcome measures between the groups.
RESULTS RESULTS
Data from 123 participants were included and revealed no statistically significant group for objective sleep and physical activity parameters. The CS group, however, presented with worse self-reported sleep (quality sleep, insomnia severity, and dysfunctional beliefs about sleep), increased mental and physical fatigue, and higher psychological distress (anxiety and depressive symptoms), and reported lower PPTs.
CONCLUSIONS CONCLUSIONS
symptoms of CS may influence perceived sleep and affect functional health and well-being perception but do not seem to affect objective sleep and physical activity.

Identifiants

DOI: 10.3390/healthcare11243152 PMID: 38132043
pubmed: 38132043
pii: healthcare11243152
doi: 10.3390/healthcare11243152
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : São Paulo Research Foundation
ID : 2018/26103-4
Organisme : São Paulo Research Foundation
ID : 2021/09520-3
Organisme : Fonds Wetenschappelijk Onderzoek - Toegepast Biomedisch Onderzoek
ID : T001117N

Auteurs

Lucas Araújo Almeida (L)

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Laarbeeklaan 103-Building F, 1090 Brussel, Belgium.
Laboratory of Analysis and Intervention of the Shoulder Complex, Department of Physical Therapy, Universidade Federal de São Carlos, São Carlos 13565-905, SP, Brazil.
Department of Physical Therapy, University of Florida, Gainesville, FL 32611, USA.
ORCID: 0000-0002-7629-3781

Thomas Bilterys (T)

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Laarbeeklaan 103-Building F, 1090 Brussel, Belgium.
Pain in Motion International Research Group, 1090 Brussel, Belgium.
Department of Psychology, University of Warwick, Coventry CV4 7AL, UK.
Institute of Advanced Study, University of Warwick, Coventry CV4 7AL, UK.
ORCID: 0000-0002-5673-7314

Eveline Van Looveren (E)

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Laarbeeklaan 103-Building F, 1090 Brussel, Belgium.
Pain in Motion International Research Group, 1090 Brussel, Belgium.
Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, Ghent University, Campus Heymans-Building B3, De Pintelaan 185, 9000 Ghent, Belgium.
ORCID: 0000-0002-4200-1533

Olivier Mairesse (O)

Brain, Body and Cognition (BBCO), Faculty of Psychology and Educational Sciences, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
ORCID: 0000-0001-8428-1185

Barbara Cagnie (B)

Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, Ghent University, Campus Heymans-Building B3, De Pintelaan 185, 9000 Ghent, Belgium.
ORCID: 0000-0003-4342-4519

Mira Meeus (M)

Pain in Motion International Research Group, 1090 Brussel, Belgium.
Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, Ghent University, Campus Heymans-Building B3, De Pintelaan 185, 9000 Ghent, Belgium.
Department of Rehabilitation Sciences and Physiotherapy (MOVANT), Faculty of Medicine and Health Sciences, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium.
ORCID: 0000-0002-2022-5114

Maarten Moens (M)

Pain in Motion International Research Group, 1090 Brussel, Belgium.
Department of Neurosurgery and Radiology, University Hospital Brussels, 1090 Brussels, Belgium.
Stimulus Research Group, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Center of Neurosciences, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
ORCID: 0000-0003-0577-5449

Dorien Goubert (D)

Pain in Motion International Research Group, 1090 Brussel, Belgium.
Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, Ghent University, Campus Heymans-Building B3, De Pintelaan 185, 9000 Ghent, Belgium.
ORCID: 0000-0002-1387-9160

Wouter Munneke (W)

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Laarbeeklaan 103-Building F, 1090 Brussel, Belgium.
Pain in Motion International Research Group, 1090 Brussel, Belgium.
Department of Sport and Rehabilitation Sciences, University of Liège, 4000 Liege, Belgium.
ORCID: 0000-0001-6561-2823

Lieven Danneels (L)

Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, Ghent University, Campus Heymans-Building B3, De Pintelaan 185, 9000 Ghent, Belgium.
ORCID: 0000-0002-3030-2697

Kelly Ickmans (K)

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Laarbeeklaan 103-Building F, 1090 Brussel, Belgium.
Pain in Motion International Research Group, 1090 Brussel, Belgium.
Chronic Pain Rehabilitation, Department of Physical Medicine and Physiotherapy, University Hospital Brussels, 1090 Brussels, Belgium.
Movement & Nutrition for Health & Performance Research Group (MOVE), Department of Movement and Sport Sciences, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
ORCID: 0000-0003-0751-6504

Paula Rezende Camargo (P)

Laboratory of Analysis and Intervention of the Shoulder Complex, Department of Physical Therapy, Universidade Federal de São Carlos, São Carlos 13565-905, SP, Brazil.

Jo Nijs (J)

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Laarbeeklaan 103-Building F, 1090 Brussel, Belgium.
Pain in Motion International Research Group, 1090 Brussel, Belgium.
Chronic Pain Rehabilitation, Department of Physical Medicine and Physiotherapy, University Hospital Brussels, 1090 Brussels, Belgium.
Department of Health and Rehabilitation, Unit of Physiotherapy, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, 41390 Göterbog, Sweden.
ORCID: 0000-0002-4976-6563

Anneleen Malfliet (A)

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Laarbeeklaan 103-Building F, 1090 Brussel, Belgium.
Pain in Motion International Research Group, 1090 Brussel, Belgium.
Chronic Pain Rehabilitation, Department of Physical Medicine and Physiotherapy, University Hospital Brussels, 1090 Brussels, Belgium.
Research Foundation-Flanders (FWO), 1000 Brussels, Belgium.
ORCID: 0000-0003-0598-7038

Liesbet De Baets (L)

Pain in Motion Research Group (PAIN), Department of Physiotherapy, Human Physiology and Anatomy (KIMA), Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Laarbeeklaan 103-Building F, 1090 Brussel, Belgium.
Pain in Motion International Research Group, 1090 Brussel, Belgium.

Classifications MeSH