A Synthetic Model of the Mucosa for Oral Penetration Studies.
TMWL
in vitro permeation
mucosa membrane
synthetic membrane
waterproofing formulations
Journal
Membranes
ISSN: 2077-0375
Titre abrégé: Membranes (Basel)
Pays: Switzerland
ID NLM: 101577807
Informations de publication
Date de publication:
12 Dec 2023
12 Dec 2023
Historique:
received:
10
11
2023
revised:
04
12
2023
accepted:
10
12
2023
medline:
22
12
2023
pubmed:
22
12
2023
entrez:
22
12
2023
Statut:
epublish
Résumé
The main objective of this study is the evaluation of the use of a synthetic membrane, Nuclepore, as a model for permeation studies through sublingual mucosa. The permeability of two types of membranes, porcine sublingual oral mucosa and a synthetic Nuclepore membrane, to water was compared. Moreover, the water permeability of membranes modified with waterproofing formulations was measured to study their ability to protect against the penetration of viruses, toxins, etc. A relatively high correlation (R
Identifiants
pubmed: 38132909
pii: membranes13120905
doi: 10.3390/membranes13120905
pii:
doi:
Types de publication
Journal Article
Langues
eng